Results 31 to 40 of about 83,143 (263)
PLoS Neglected Tropical Diseases, 2022 Trans-sialidases (TS) represent a multi-gene family of unusual enzymes, which catalyse the transfer of terminal sialic acids (Sia) from sialoglycoconjugates to terminal galactose or N-acetylgalactosamine residues of oligosaccharides without the ...
Mario Waespy +6 more
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Linking in domain-swapped protein dimers
Scientific Reports, 2016 AbstractThe presence of knots has been observed in a small fraction of single-domain proteins and related to their thermodynamic and kinetic properties. The exchanging of identical structural elements, typical of domain-swapped proteins, makes such dimers suitable candidates to validate the possibility that mutual entanglement between chains may play a
Marco Baiesi +3 more
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Target validation:switching domains [PDF]
, 2016 Chemical probes and drugs often bind to functional domains on disease-relevant proteins. A study suggests a chemical genetic approach to establish on-target effects by swapping the targeted domain, affording resistance to pharmacological inhibition while
AC Runcie +10 more
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The Unfolding Story of Three-Dimensional Domain Swapping [PDF]
Structure, 2003 Three-dimensional domain swapping is the event by which a monomer exchanges part of its structure with identical monomers to form an oligomer where each subunit has a similar structure to the monomer. The accumulating number of observations of this phenomenon in crystal structures has prompted speculation as to its biological relevance. Domain swapping
Rousseau, Frederic +2 more
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Genome-Wide Analysis of Domain-Swap Predicted Products in the Genome of Anti-Stress Medicinal Plant:
Bioinformatics and Biology Insights, 2019 Computational approaches to high-throughput data are gaining importance because of explosion of sequences in the post-genomic era. This explosion of sequence data creates a huge gap among the domains of sequence structure and function, since the ...
Atul Kumar Upadhyay +1 more
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The Making of a Slicer: Activation of Human Argonaute-1
Cell Reports, 2013 Argonautes are the central protein component in small RNA silencing pathways. Of the four human Argonautes (hAgo1–hAgo4) only hAgo2 is an active slicer.
Christopher R. Faehnle +4 more
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Fast and rewritable colloidal assembly via field synchronized particle swapping [PDF]
, 2014 We report a technique to realize reconfigurable colloidal crystals by using the controlled motion of particle defects above an externally modulated magnetic substrate. The transport of particles is induced by applying a uniform rotating magnetic field to
Häfeli U. +3 more
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Cut-touching linear functionals in the conformal bootstrap
, 2017 The modern conformal bootstrap program often employs the method of linear functionals to derive the numerical or analytical bounds on the CFT data. These functionals must have a crucial "swapping" property, allowing to swap infinite summation with the ...
Qiao, Jiaxin, Rychkov, Slava
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Domain swapping: entangling alliances between proteins. [PDF]
Proceedings of the National Academy of Sciences, 1994 The comparison of monomeric and dimeric diphtheria toxin (DT) reveals a mode for protein association which we call domain swapping. The structure of dimeric DT has been extensively refined against data to 2.0-A resolution and a three-residue loop has been corrected as compared with our published 2.5-A-resolution structure.
M J, Bennett, S, Choe, D, Eisenberg
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The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid. [PDF]
, 2013 The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core ...
A Moya +48 more
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