Results 61 to 70 of about 713,409 (294)

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

open access: yesPopulation Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi   +3 more
wiley   +1 more source

Quantitative trait loci for bone traits segregating independently of those for growth in an F-2 broiler X layer cross [PDF]

open access: yes, 2007
An F broiler-layer cross was phenotyped for 18 skeletal traits at 6, 7 and 9 weeks of age and genotyped with 120 microsatellite markers. Interval mapping identified 61 suggestive and significant QTL on 16 of the 25 linkage groups for 16 traits.
A.S. Law   +29 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Modeling Haplotype-Haplotype Interactions in Case-Control Genetic Association Studies

open access: yesFrontiers in Genetics, 2012
Haplotype analysis has been increasingly used to study the genetic basis of human diseases, but models for characterizing genetic interactions between haplotypes from different chromosomal regions have not been well developed in the current literature ...
Li eZhang   +4 more
doaj   +1 more source

Detection of quantitative trait loci for locomotion and osteochondrosis-related traits in Large White x Meishan pigs. [PDF]

open access: yes, 2003
Data from the F2 generation of a Large White (LW) 5 Meishan (MS) crossbred population were analysed to detect quantitative trait loci (QTL) for leg and gait scores, osteochondrosis and physis scores.
Archibald, Alan   +6 more
core  

20 questions on Adaptive Dynamics [PDF]

open access: yes, 2005
Adaptive Dynamics is an approach to studying evolutionary change when fitness is density or frequency dependent. Modern papers identifying themselves as using this approach first appeared in the 1990s, and have greatly increased up to the present ...
Abrams   +91 more
core   +2 more sources

Dominance and epistatic genetic variances for litter size in pigs using genomic models

open access: yesGenetics Selection Evolution, 2018
Epistatic genomic relationship matrices for interactions of any-order can be constructed using the Hadamard products of orthogonal additive and dominance genomic relationship matrices and standardization based on the trace of the resulting matrices ...
Z. Vitezica   +3 more
semanticscholar   +1 more source

The pushback against state interference in science: how Lysenkoism tried to suppress Genetics and how it was eventually defeated.

open access: yesGenetics, 2021
Genetics in the Soviet Union (USSR) achieved state-of-the-art results and had reached a peak of development by the mid-1930s due to the efforts of the scientific schools of several major figures, including Sergei Navashin, Nikolai Koltsov, Grigorii ...
V. Ptushenko
semanticscholar   +1 more source

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