Results 71 to 80 of about 37,774 (258)

Predictors of a Gabapentinoid–Loop‐Diuretic Prescribing Cascade in U.S. Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
Among 23,544 older adult long‐stay nursing home residents who initiated a gabapentinoid in the nursing home (2016–2022), 4.2% experienced a loop diuretic prescribing cascade within 90 days. Predictors of the prescribing cascade included older age, higher medication burden (≥ 15 medications), current receipt of non‐loop diuretics, and titration of ...
Kaleen N. Hayes, Emmanuelle Belanger, Arman Oganisian, Richa Joshi, Xiao (Joyce) Wang, Lexie R. Grove, Kelsey L. Corcoran, Andrew R. Zullo   +7 more
wiley   +1 more source

Evaluating High-Dose Rivastigmine Patch in Severe Alzheimer’s Disease: Analyses with Concomitant Memantine Usage as a Factor [PDF]

, 2015
Background: ACTION, a 24-week, prospective, randomized, parallel-group, double-blind study in patients with severe Alzheimer’s disease (AD), demonstrated significant efficacy of 13.3 mg/24 h versus 4.6 mg/24 h rivastigmine patch on the Severe Impairment ...
Farlow, Martin R., Grossberg, George T., Meng, Xiangyi, Velting, Drew M.   +3 more
core   +1 more source

A Retrospective Chart Review of the Prevalence, Characteristics, and Discharge Destinations of Patients Hospitalized as “Social Admissions”

Journal of the American Geriatrics Society, EarlyView.
Overview of study.
Jasmine Mah, Lucy Eum, Lindsey Puddicombe, Christie Stilwell, Karen Nicholls, Hamish Frayne, Clara Long, Kristin Ko, Victoria Howatt, Margaret Man‐Ger Sun, Lynnea Lobert, Gali Latariya, Katalin Koller, Susan Freter, Maia von Maltzahn, Kenneth Rockwood, Samuel D. Searle, Melissa K. Andrew   +17 more
wiley   +1 more source

The Efficacy of Licensed-Indication Use of Donepezil and Memantine Monotherapies for Treating Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer’s Disease: Systematic Review and Meta-Analysis

Dementia and Geriatric Cognitive Disorders Extra, 2011
Background/Aims: Behavioural and psychological symptoms of dementia (BPSD) in Alzheimer’s disease (AD) greatly increase caregiver burden. The abilities of donepezil and memantine to manage BPSD within their licensed indications in AD were compared ...
I.A. Lockhart, M.E. Orme, S.A. Mitchell
doaj   +1 more source

Validity, Significance, Strengths, Limitations, and Evidentiary Value of Real-World Clinical Data for Combination Therapy in Alzheimer's Disease: Comparison of Efficacy and Effectiveness Studies [PDF]

, 2014
Background: Randomized controlled efficacy trials (RCTs), the scientific gold standard, are required for regulatory approval of Alzheimer's disease (AD) interventions, yet provide limited information regarding real-world therapeutic effectiveness ...
Atri, Alireza, Doody, Rachelle S., Lopez, Oscar L., Rountree, Susan D.   +3 more
core   +1 more source

Sensorimotor Impairment and Incident Dementia in the US Medicare Beneficiaries

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Sensorimotor impairments, including sensory (vision and hearing) and motor (standing balance, gait, chair stands, grip strength) deficits, are prevalent in older adults and are associated with an increased risk of dementia. Understanding the individual and combined effects of these impairments on dementia risk may enhance early ...
Anis Davoudi, Ryan J. Dougherty, Amal A. Wanigatunga, Yuri Agrawal, Nicholas S. Reed, Joshua R. Ehrlich, Alden L. Gross, Jennifer A. Schrack   +7 more
wiley   +1 more source

Emerging pharmacotherapy for cancer patients with cognitive dysfunction [PDF]

, 2013
Advances in the diagnosis and multi-modality treatment of cancer have increased survival rates for many cancer types leading to an increasing load of long-term sequelae of therapy, including that of cognitive dysfunction.
A Parachikova, A Prakash, B Gagnon, BP Daly, C Cunningham, C Gottesmann, CD Aluise, CJ Nelson, CM Reid, D Greene-Schloesser, D Holmes, D Jaturapatporn, D Kim, David M Ashley, DD Correa, EE Lower, EG Shaw, EJ Jacobs, EM Yazlovitskaya, ES Yang, F Joly, F Xia, Fiona M Ahlberg, G Winocur, G Winocur, H Cimarosti, HG Mar Fan, HM Conklin, J Kim, J Lindsay, JC Adair, JH Kang, JM Leoutsakos, JS Wefel, JS Wefel, JS Wefel, Justin Davis, K Gehring, K Hermelink, K Hermelink, L Blackhall, L Lundorff, M Batalo, M Berbee, M Berk, M Inouye, M Khasraw, M Khasraw, M Khasraw, MC Janelsins, ME Robbins, Michael Berk, MJR Howes, Mustafa Khasraw, N Biglia, N Volkow, PD Brown, RK Mulhern, S Kohli, SJ Thompson, SM Castellino, T Scammell, TE Wilens, TM Engber, V Dutta, V Tiwari, W Lasheen, Y Liu   +67 more
core   +2 more sources

Association of Palliative Care Initiation With Acute Healthcare Utilization Among Community‐Dwelling Adults Living With Dementia

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Objectives To measure the association between initiating palliative care using the combined criteria of short survival expectations and increased care needs with acute healthcare utilization among community‐dwelling people living with dementia. Design A population‐level propensity‐based overlap‐weighted cohort study.
Kieran L. Quinn, Thérèse A. Stukel, Michael Pugliese, Allan S. Detsky, George Heckman, Mariam Toluwalashe Omilabu, Nathan M. Stall, Desiree Vaz, Colleen Webber, Peter Tanuseputro, Sarina Isenberg   +10 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Neuroprotection against vascular dementia after acupuncture combined with donepezil hydrochloride: P300 event related potential

Neural Regeneration Research, 2016
Acupuncture can be used to treat various nervous system diseases. Here, 168 vascular dementia patients were orally administered donepezil hydrochloride alone (5 mg/day, once a day for 56 days), or combined with acupuncture at Shenting (DU24), Tianzhu ...
Qiang Liu, Xiu-juan Wang, Zhe-cheng Zhang, Rong Xue, Ping Li, Bo Li   +5 more
doaj   +1 more source