Males are worse mothers: Comparing care patterns in a facultatively caring beetle
Insect Science, EarlyView.Why should biparental care exist if offspring fare just as well when only one parent is present? In the facultatively dependent burying beetle, Nicrophorus vespilloides, manipulating environmental quality reveals that biparental care benefits offspring in form of lower personal immune requirement and parents in term of weight gain.
Leon Müller +2 more
wiley +1 more source
Evaluation of growth hormone provocative tests in Egyptian children with growth hormone-related short stature. [PDF]
World J Exp MedAhmed AE +3 more
europepmc +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Interactions of the Tricyclic Antidepressant Drug Amitriptyline with L-DOPA in the Nucleus Accumbens, Prefrontal Cortex and Hippocampus of Unilaterally 6-OHDA-Lesioned Rats: Relevance to Depression in Parkinson's Disease. [PDF]
BiomoleculesKamińska K +3 more
europepmc +1 more source
Cancer Science, EarlyView.Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa +13 more
wiley +1 more source
Heterologous expression of hydroxylase coupled with pathway optimization enables highly efficient ʟ-DOPA production in <i>Corynebacterium glutamicum</i>. [PDF]
Synth Syst BiotechnolJia M +7 more
europepmc +1 more source
Microbiome‐mediated immunity: Limited support from the gazelle dung beetle
Ecological Entomology, EarlyView.Digitonthophagus gazella rely on a maternally inherited microbiome passed across generations via a maternal faecal pellet called the pedestal. We experimentally manipulated the presence of the pedestal, providing it to some individuals while withholding it from others to determine how pedestal microbiota may affect beetle immune potential.
Joshua A. Jones +2 more
wiley +1 more source
L-Dopa/Carbidopa intestinal gel infusion in advanced Parkinson's disease: real-life mobility insights from wearable sensors. [PDF]
Front NeurolZampogna A +10 more
europepmc +1 more source
L-DOPA mõju sensoorsele funktsioonile in vivo
Levodopa (L-DOPA) is a compound that is used as a key medication in treating Parkinson’s disease (PD), particularly in managing bradykinetic symptoms of the disorder.
Rusetskaya, Anna
core
The FEBS Journal, EarlyView.Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source