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Annual Review of Psychology, 2020 Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is usually defined by characteristics of intoxication or by characteristics of withdrawal symptoms. Such addictions can also be defined in terms of the brain mechanisms they activate; most addictive drugs cause elevations in extracellular levels of the ...
Roy A Wise, Roy A Wise, Mykel A. Robble
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Molecular simulation study of RNA/dopamine complex dynamics at varying concentrations [PDF]
Scientific ReportsThe interaction between dopamine and RNA structures holds significant potential for understanding neurotransmitter-driven RNA modulation and biosensor design.
Armen H. Poghosyan +5 more
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RGSB-UNet: Hybrid Deep Learning Framework for Tumour Segmentation in Digital Pathology Images
Bioengineering, 2023 Colorectal cancer (CRC) is a prevalent gastrointestinal tumour with high incidence and mortality rates. Early screening for CRC can improve cure rates and reduce mortality.
Tengfei Zhao +4 more
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AFFNet: An Attention-Based Feature-Fused Network for Surface Defect Segmentation
Applied Sciences, 2023 Recently, deep learning methods have widely been employed for surface defect segmentation in industrial production with remarkable success. Nevertheless, accurate segmentation of various types of defects is still challenging due to their irregular ...
Xiaodong Chen +4 more
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Automatic Segmentation of Cervical Cells Based on Star-Convex Polygons in Pap Smear Images
Bioengineering, 2022 Cervical cancer is one of the most common cancers that threaten women’s lives, and its early screening is of great significance for the prevention and treatment of cervical diseases.
Yanli Zhao +5 more
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Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. [PDF]
PLoS Biology, 2005 Brain dopamine is critically involved in movement control, and its deficiency is the primary cause of motor symptoms in Parkinson disease. Here we report development of an animal model of acute severe dopamine deficiency by using mice lacking the ...
Tatyana D Sotnikova +5 more
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Dopamine, Immunity, and Disease
Pharmacological Reviews, 2022 The neurotransmitter dopamine is a key factor in central nervous system (CNS) function, regulating many processes including reward, movement, and cognition.
Breana Channer +6 more
semanticscholar +1 more source
Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia
Neurobiology of Disease, 2021 TOR1A-associated dystonia, otherwise known as DYT1 dystonia, is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE).
Anthony M. Downs +5 more
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Pharmaceuticals, 2023 We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric +24 more
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Conformation of dopamine at the dopamine receptor. [PDF]
Proceedings of the National Academy of Sciences, 1978 Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
Duane D. Miller +3 more
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