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Mesolimbic dopamine ramps reflect environmental timescales [PDF]
eLifeMesolimbic dopamine activity occasionally exhibits ramping dynamics, reigniting debate on theories of dopamine signaling. This debate is ongoing partly because the experimental conditions under which dopamine ramps emerge remain poorly understood.
Joseph R Floeder +3 more
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KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant [PDF]
, 2015 Dopamine D-4 Receptor Polymorphism : The dopamine D-4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit ...
Lintermans, Béatrice +3 more
core +23 more sources
RGSB-UNet: Hybrid Deep Learning Framework for Tumour Segmentation in Digital Pathology Images
Bioengineering, 2023 Colorectal cancer (CRC) is a prevalent gastrointestinal tumour with high incidence and mortality rates. Early screening for CRC can improve cure rates and reduce mortality.
Tengfei Zhao +4 more
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AFFNet: An Attention-Based Feature-Fused Network for Surface Defect Segmentation
Applied Sciences, 2023 Recently, deep learning methods have widely been employed for surface defect segmentation in industrial production with remarkable success. Nevertheless, accurate segmentation of various types of defects is still challenging due to their irregular ...
Xiaodong Chen +4 more
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Automatic Segmentation of Cervical Cells Based on Star-Convex Polygons in Pap Smear Images
Bioengineering, 2022 Cervical cancer is one of the most common cancers that threaten women’s lives, and its early screening is of great significance for the prevention and treatment of cervical diseases.
Yanli Zhao +5 more
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Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. [PDF]
PLoS Biology, 2005 Brain dopamine is critically involved in movement control, and its deficiency is the primary cause of motor symptoms in Parkinson disease. Here we report development of an animal model of acute severe dopamine deficiency by using mice lacking the ...
Tatyana D Sotnikova +5 more
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Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia
Neurobiology of Disease, 2021 TOR1A-associated dystonia, otherwise known as DYT1 dystonia, is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE).
Anthony M. Downs +5 more
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Pharmaceuticals, 2023 We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric +24 more
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Electrochemical Aptasensor for Detection of Dopamine [PDF]
, 2020 This work presents a proof of concept of a novel, simple, and sensitive method of detection of dopamine, a neurotransmitter within the human brain. We propose a simple electrochemical method for the detection of dopamine using a dopamine-specific aptamer
Abu-Ali, Hisham +4 more
core +1 more source
Frontiers in Cellular Neuroscience, 2022 The piriform cortex (PCx) is essential for the adaptive processing of olfactory information. Neuromodulatory systems, including those utilizing serotonin, acetylcholine, noradrenaline, and dopamine, innervate and regulate neuronal activity in the PCx ...
Yasmin Potts, John M. Bekkers
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