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Dopamine and Addiction. [PDF]

open access: yesAnnual Review of Psychology, 2020
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is usually defined by characteristics of intoxication or by characteristics of withdrawal symptoms.
R. Wise, Mykel A. Robble
semanticscholar   +3 more sources

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

open access: yesFrontiers in Aging Neuroscience, 2019
Background: The dopaminergic system has been associated with the progression of Alzheimer's disease. But previous studies found inconsistent results regarding the relationship between Alzheimer's disease and dopamine when looking at dopamine receptor ...
Xiongfeng Pan   +9 more
doaj   +2 more sources

AFFNet: An Attention-Based Feature-Fused Network for Surface Defect Segmentation

open access: yesApplied Sciences, 2023
Recently, deep learning methods have widely been employed for surface defect segmentation in industrial production with remarkable success. Nevertheless, accurate segmentation of various types of defects is still challenging due to their irregular ...
Xiaodong Chen   +4 more
doaj   +1 more source

RGSB-UNet: Hybrid Deep Learning Framework for Tumour Segmentation in Digital Pathology Images

open access: yesBioengineering, 2023
Colorectal cancer (CRC) is a prevalent gastrointestinal tumour with high incidence and mortality rates. Early screening for CRC can improve cure rates and reduce mortality.
Tengfei Zhao   +4 more
doaj   +1 more source

Automatic Segmentation of Cervical Cells Based on Star-Convex Polygons in Pap Smear Images

open access: yesBioengineering, 2022
Cervical cancer is one of the most common cancers that threaten women’s lives, and its early screening is of great significance for the prevention and treatment of cervical diseases.
Yanli Zhao   +5 more
doaj   +1 more source

Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. [PDF]

open access: yesPLoS Biology, 2005
Brain dopamine is critically involved in movement control, and its deficiency is the primary cause of motor symptoms in Parkinson disease. Here we report development of an animal model of acute severe dopamine deficiency by using mice lacking the ...
Tatyana D Sotnikova   +5 more
doaj   +2 more sources

From Selye’s and Szabo’s Cysteamine-Duodenal Ulcer in Rats to Dopamine in the Stomach: Therapy Significance and Possibilities

open access: yesPharmaceuticals, 2023
We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric   +24 more
doaj   +1 more source

Dopamine Increases the Intrinsic Excitability of Parvalbumin-Expressing Fast-Spiking Cells in the Piriform Cortex

open access: yesFrontiers in Cellular Neuroscience, 2022
The piriform cortex (PCx) is essential for the adaptive processing of olfactory information. Neuromodulatory systems, including those utilizing serotonin, acetylcholine, noradrenaline, and dopamine, innervate and regulate neuronal activity in the PCx ...
Yasmin Potts, John M. Bekkers
doaj   +1 more source

Conformation of dopamine at the dopamine receptor. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1978
Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
Duane D. Miller   +3 more
openaire   +3 more sources

Decoding the dopamine signal in macaque prefrontal cortex: a simulation study using the Cx3Dp simulator. [PDF]

open access: yesPLoS ONE, 2013
Dopamine transmission in the prefrontal cortex plays an important role in reward based learning, working memory and attention. Dopamine is thought to be released non-synaptically into the extracellular space and to reach distant receptors through ...
Isabelle Ayumi Spühler, Andreas Hauri
doaj   +1 more source

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