Results 41 to 50 of about 278,985 (182)
Modulation of Adenylyl Cyclase Activity in Rat Striatal Homogenate by Dopaminergic Receptors
We have characterized the modulation of adenylyl cyclase (AC) activity by ligands of dopaminergic receptors in rat striatal homogenate and compared the results with receptor-ligand binding affinities.
Argo Vonk, Reet Reinart, Ago Rinken
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Dopamine-Deficient Mice Are Hypersensitive to Dopamine Receptor Agonists
Dopamine-deficient (DA−/−) mice were created by targeted inactivation of the tyrosine hydroxylase gene in dopaminergic neurons. The locomotor activity response of these mutants to dopamine D1 or D2 receptor agonists andl-3,4-dihydroxyphenylalanine (l ...
Mark S. Szczypka +2 more
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We aimed to investigate the integrity and clinical relevance of striatal dopamine receptor type-2 (D2R) availability in Parkinson's disease (PD) patients. We studied 68 PD patients, spanning from early to advanced disease stages, and 12 healthy controls.
Marios Politis +4 more
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Dopamine Partial Agonists in Pregnancy and Lactation: A Systematic Review
Background/Objectives: Dopamine partial agonists are drugs initially developed to treat schizophrenia, seeking a double effect of increased dopaminergic transmission in the prefrontal cortex and decrease in the accumbens/striatum.
Alexia Koukopoulos +13 more
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Mythology of Parkinson’s disease: from levodopa phobia to dopamine agonist phobia
Any common disease (including Parkinson’s disease) is inevitably overgrown with myths. As a result, not scientifically grounded approaches based on the principles of evidence-based medicine, but irrational ideas, especially often of a pharmacophobic ...
O. S. Levin +2 more
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Dopamine agonists, receptor selectivity and dyskinesia induction in Parkinson's disease
Levodopa and the dopamine agonists are effective symptomatic treatments for Parkinson's disease, and all patients receive at least one of these agents during their illness. Long-term use of levodopa is commonly associated with motor complications such as
Jenner, P
core +3 more sources
Pharmacology of dopamine agonists in the treatment of Parkinson's disease
There is now increasing use of dopamine agonists as effective early monotherapy in the treatment of Parkinson's disease (PD). Dopamine agonists can induce an antiparkinsonian effect through actions on either D-1-like or D-2-like dopamine receptors, and ...
Jenner, P
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Pharmacology of novel psychoactive substances [PDF]
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
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Dopamine agonists for treatment of restless legs syndrome
The restless legs syndrome (RLS) is characterized by dysaesthesias of the legs associated with an urge to move which occurs at rest and during the night and can be ameliorated by activity. Treatment with levodopa leads to symptom relief, but augmentation
Happe, Svenja
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Three cases of delusional parasitosis caused by dopamine agonists
P>We report three cases of delusional parasitosis (DP) in patients with well-established Parkinson's disease, all of whom were taking dopamine agonists.
Flann, S. +13 more
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