Results 61 to 70 of about 278,985 (182)

Prescribing pattern of anti-Parkinson drugs in Japan: a trend analysis from 2005 to 2010.

open access: yesPLoS ONE, 2014
ObjectiveTherapeutic options for Parkinson's disease mainly consist of L-dopa and dopamine agonists. However, in Japan, the product labeling of the ergot dopamine agonists, cabergoline and pergolide, was revised in April 2007 due to the risk of ...
Sachiko Nakaoka   +6 more
doaj   +1 more source

Pramipexole use and the risk of pneumonia

open access: yesBMC Neurology, 2012
Background Patients with Parkinson's disease have an elevated risk of pneumonia and randomized trials suggest that this risk may be increased with the dopamine agonist pramipexole.
Ernst Pierre   +3 more
doaj   +1 more source

New information of dopaminergic agents based on quantum chemistry calculations

open access: yesScientific Reports, 2020
Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson’s disease and Huntington’s disease ...
Guillermo Goode-Romero   +6 more
doaj   +1 more source

Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships [PDF]

open access: yes, 2008
Potent and selective histamine H2 receptor (H2R) agonists are valuable pharmacological tools and might be of therapeutic value as drugs, for example in the treatment of severe congestive heart failure.
Kraus, Anja
core   +1 more source

Activation of Dopamine D4 Receptors Is Protective Against Hypoxia/ Reoxygenation-Induced Cell Death in HT22 Cells

open access: yesJournal of Pharmacological Sciences, 2010
Several reports have shown that some dopamine receptor ligands modulate the ischemia–reperfusion injury in animal models; however, its underling mechanisms are still unclear. In this study, we sought to establish an in vitro experimental model of hypoxia/
Saori Shimada   +5 more
doaj   +1 more source

NEW DOPAMINE AGONISTS IN CARDIOVASCULAR THERAPY

open access: yes, 1992
Dopamine, a naturally occurring catecholamine, has been extensively used in intensive care for many years. Dopamine stimulates different types of adrenergic receptors: alpha-1 and -2, beta-1 and -2, and dopamine-1 and -2.
SMIT, AJ, GIRBES, ARJ, VANVELDHUISEN, DJ
core   +1 more source

Dopamine receptor agonists mediate neuroprotection in malonate-induced striatal lesion in the rat

open access: yes, 2002
Mitochondrial bioenergetic defects are involved in neurological disorders associated with neuronal damage in the striatum, such as Huntington's disease and cerebral ischemia.
Nappi G.   +3 more
core   +1 more source

Do neurologists in Germany adhere to the national Parkinson's disease guideline?

open access: yesNeuropsychiatric Disease and Treatment, 2011
Sabrina Schröder1, Daniel Kuessner2, Guy Arnold3, York Zöllner4, Eddie Jones5, Marion Schaefer11Institute of Clinical Pharmacology, Charité University Medicine, CCM, Berlin, Germany; 2Basilea Pharmaceutica, Basel, Switzerland;
Sabrina Schröder   +3 more
doaj  

Chapter 34 - Dopamine replacement for Parkinson's disease: Clinical approaches and experimental underpinnings

open access: yes
Parkinson's disease (PD) is characterized by a set of motor symptoms that depend on nigrostriatal dopaminergic degeneration and respond well to pharmacological dopamine replacement using L-DOPA.
Rosqvist, Kristina   +6 more
core   +1 more source

Dopamine D1 receptor agonists induce penile erections in rats

open access: yes, 2003
The dopamine receptor agonist apomorphine has been recently introduced in the treatment of erectile dysfunction. While it is well established that dopamine D2-like receptors play a crucial role in this effect, conflicting result are reported in the ...
D'Aquila, Paolo Stefano   +9 more
core   +1 more source

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