Results 71 to 80 of about 278,985 (182)

Effects of L-Dopa and Dopamine D2 Agonists on Recollection and Familiarity in Idiopathic Nondementing Parkinson’s Disease [PDF]

open access: yes, 2011
Idiopathic nondementing Parkinson’s disease (PD) is marked by progressive loss of dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area.
Edelstyn
core   +1 more source

A review of adverse events linked to dopamine agonists in the treatment of Parkinson's disease.

open access: yes, 2015
Introduction: Dopamine agonists are highly effective as adjunctive therapy to levodopa in advanced Parkinson's disease. These drugs have rapidly gained popularity as a monotherapy in the early stages of Parkinson's disease for patients less than 65-70 ...
CERAVOLO, ROBERTO   +3 more
core  

Ha-117 and Ha-118 are potent dopamine receptor agonists

open access: yes, 1984
In-vitro studies evaluated the presynaptic dopamine receptor activities of trans-N-propyl-7,9-dihydroxyoctahydrobenzo[f]quinoline (Ha-117) and trans-N-ethyl-7,9-dihydroxyoctahydrobenzo[f]quinoline (Ha-118) using isolated field-stimulated cat right atria.
Joseph G Cannon   +2 more
core   +1 more source

Serotonergic agonists behave as partial agonists at the dopamine D2 receptor

open access: yes, 1999
RAT dopamine D2short receptors expressed in CHO cells were characterized by activation of [35S]GTPgammaS binding. There were no significant differences between the maximal effects seen in activation of [35S]GTPgammaS binding caused by dopaminergic ...
Owman, C   +6 more
core   +1 more source

Dopamine Agonist Prescribing in a Gambling Disorder Patient Population: A Clinical Audit to Determine Prevalence in the NHS Northern Gambling Service

open access: yesBJPsych Open
Aims: Dopamine agonists are prescribed to treat several major physical and mental illnesses. Rotigotine, ropinerole, pramipexole (full agonists) are routinely used to treat symptoms of restless leg syndrome, whilst aripiprazole (partial agonist) is used ...
John Barker, Rebecca Lees
doaj   +1 more source

Neuroprotective effects mediated by dopamine receptor agonists against malonate-induced lesion in the rat striatum

open access: yes, 2003
In rats, intrastriatal injection of malonate, a reversible inhibitor of the mitochondrial enzyme succinate dehydrogenase, induces a lesion similar to that observed following focal ischemia or in Huntington's disease.
Nappi G.   +3 more
core   +1 more source

Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression

open access: yes, 1994
We compared the effect of two selective dopamine D1 receptor agonists, SKF 38393 ((±)-1-phenyl-2,3,4,5-tetrahydro-(1H)- 3-benzazepine-7,8-diol · HCl) and A68930 ((1R,3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman · HCl), and that of imipramine in the
Pani L.   +4 more
core   +1 more source

Cost-Effectiveness Analysis of Dopamine Agonists in the Treatment of Parkinson's Disease in Japan

open access: yes
Background: Dopamine agonists such as bromocriptine or pergolide are often used in Japan to treat Parkinson's disease. Dopamine agonists are relatively expensive drugs; economic evaluations are required.
Kenji Hira   +3 more
core  

Resistance to dopamine agonists in prolactinoma is correlated with reduction of dopamine D2 receptor long isoform mRNA levels

open access: yes, 2012
ObjectiveDopamine agonists normalize prolactin (PRL) levels and reduce tumour size in responsive prolactinoma. However, several cases have shown resistance to dopamine agonists upon initial treatment.
Satoko Shimazu   +6 more
core   +1 more source

Dopamine agonists and risk of lung cancer in patients with restless legs syndrome. [PDF]

open access: yesPharmacoepidemiol Drug Saf, 2023
Hernandez-Con P   +3 more
europepmc   +1 more source

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