Results 81 to 90 of about 567,668 (313)

Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing‐off Symptoms

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) often involves motor fluctuations and dyskinesia, which are difficult to manage with medication alone. Conventional deep brain stimulation (cDBS) effectively alleviates symptoms but has limitations, including the challenge of balancing therapeutic effects against potential side effects, as well as limited ...
Takuto Emura, Naoki Tani, Koichi Hosomi, Yuki Kimoto, Takahiro Matsuhashi, Takahiro Fujinaga, Shimpei Miura, Yuya Fujita, Nobuhiko Mori, Hui Ming Khoo, Satoru Oshino, Haruhiko Kishima   +11 more
wiley   +1 more source

Pramipexole use and the risk of pneumonia

BMC Neurology, 2012
Background Patients with Parkinson's disease have an elevated risk of pneumonia and randomized trials suggest that this risk may be increased with the dopamine agonist pramipexole.
Ernst Pierre, Renoux Christel, Dell'Aniello Sophie, Suissa Samy   +3 more
doaj   +1 more source

The Feasibility and Practical Utility of Virtual Visits for Patients with Parkinson's Disease in Different World Regions

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Overcoming existing access barriers is crucial for better‐specialized health care of patients with Parkinson's disease (PD). Objective The aim of the study was to compare the access and visit quality/acceptability between in‐office and virtual telemedicine visits.
Álvaro García‐Bustillo, Jinyoung Youn, Jong Hyeon Ahn, Oluwadamilola Ojo, Njideka Okubadejo, Zakiyah Aldaajani, Mohamed Essam, Ali Shalash, Adriana Cardozo, Meredith Spindler, Zoltan Mari, Esther Cubo   +11 more
wiley   +1 more source

Activation of Dopamine D4 Receptors Is Protective Against Hypoxia/ Reoxygenation-Induced Cell Death in HT22 Cells

Journal of Pharmacological Sciences, 2010
Several reports have shown that some dopamine receptor ligands modulate the ischemia–reperfusion injury in animal models; however, its underling mechanisms are still unclear. In this study, we sought to establish an in vitro experimental model of hypoxia/
Saori Shimada, Mioko Hirabayashi, Kumiko Ishige, Yasuhiro Kosuge, Tetsuro Kihara, Yoshihisa Ito   +5 more
doaj   +1 more source

GaS/GaOLF-dependent pharmacological profile in vitro and in vivo of a novel dopamine D1 receptor agonist [PDF]

, 2022
Anh Minh Nguyen
openalex   +1 more source

Do neurologists in Germany adhere to the national Parkinson's disease guideline?

Neuropsychiatric Disease and Treatment, 2011
Sabrina Schröder1, Daniel Kuessner2, Guy Arnold3, York Zöllner4, Eddie Jones5, Marion Schaefer11Institute of Clinical Pharmacology, Charité University Medicine, CCM, Berlin, Germany; 2Basilea Pharmaceutica, Basel, Switzerland;
Sabrina Schröder, Daniel Kuessner, Guy Arnold, et al   +3 more
doaj  

The Dopamine Agonist Bromocriptine Differentially Affects Fronto-Striatal Functional Connectivity During Working Memory [PDF]

, 2011
Deanna L. Wallace, Jason Vytlacil, Emi Nomura, Sasha E. B. Gibbs, Mark D’Esposito   +4 more
openalex   +1 more source

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi, Katherine A. Grosset, Prasanth A. Iruthayaraj, Romel Gravesande, Lance Lee, Cathal Doyle, Yoav Ben‐Shlomo, Donald G. Grosset   +7 more
wiley   +1 more source

Clinical Algorithm‐Guided Approach to Botulinum Toxin Type A Treatment for Axial Postural Abnormalities in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Axial postural abnormalities (APAs) are common, disabling complications of Parkinson's disease (PD) with unclear pathophysiology. The presence of hyperactivity in multiple trunk muscles supports the use of botulinum toxin (BTA). However, its application is complex, due to the lack of standardized clinical and electrophysiological ...
Giacomo Argenziano, Giovanna Squintani, Serena Camozzi, Ilaria Di Vico, Marialuisa Gandolfi, Carlo Alberto Artusi, Michele Tinazzi, Christian Geroin   +7 more
wiley   +1 more source

A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Pharmaceuticals, 2011
Sigma1 receptors (σ1Rs) represent a structurally unique class of intracellular proteins that function as chaperones. σ1Rs translocate from the mitochondria-associated membrane to the cell nucleus or cell membrane, and through protein-protein interactions
Shang-Yi Tsai, Theresa Kopajtic, Takato Hiranita, Teruo Hayashi, Gianluigi Tanda, Jonathan L. Katz, Tsung-Ping Su   +6 more
doaj   +1 more source