Results 21 to 30 of about 312,634 (355)

A Role for Adenosine A1 Receptors in GABA and NMDA-Receptor Mediated Modulation of Dopamine Release: Studies Using Fast Cyclic Voltammetry

Sensors, 2008
In the striatum many neurotransmitters including GABA, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. Dopamine release in the striatum is regulated by a number of pre- and postsynaptic receptors
Carmel O’Neill, John J. O’Connor   +1 more
doaj   +1 more source

Knockout of Dopamine D3 Receptor Gene Blocked Methamphetamine-Induced Distinct Changes of Dopaminergic and Glutamatergic Synapse in the Nucleus Accumbens Shell of Mice

Frontiers in Cellular Neuroscience, 2022
Structural plasticity changes in the brain are thought to underlie, at least partially, drug-induced persistent changes in behavior. Our previous study reported that increased synaptic density in the nucleus accumbens shell (NAcsh) correlates with and ...
Shuai Wang, Shuai Wang, Ming Li, Ming Li, Linlan Su, Linlan Su, Yu Wang, Yu Wang, Dongliang Ma, Hongyan Wang, Hongyan Wang, Jie Zhu, Jie Zhu, Teng Chen, Teng Chen   +14 more
doaj   +1 more source

Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions

BMC Musculoskeletal Disorders, 2011
Background Control of skeletal muscle mass and force production is a complex physiological process involving numerous regulatory systems. Agents that increase skeletal muscle cAMP levels have been shown to modulate skeletal muscle mass and force ...
Dietrich Jeffrey A, Dolan Elizabeth T, Lefever Frank R, Hinkle Richard T, Reichart Deborah L, Sibley David R, Isfort Robert J   +6 more
doaj   +1 more source

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

Respiratory Research, 2018
Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
Nao Matsuyama, Sumire Shibata, Atsuko Matoba, Tada-aki Kudo, Jennifer Danielsson, Atsushi Kohjitani, Eiji Masaki, Charles W. Emala, Kentaro Mizuta   +8 more
doaj   +1 more source

Peripheral Dopamine Directly Acts on Insulin-Sensitive Tissues to Regulate Insulin Signaling and Metabolic Function

Frontiers in Pharmacology, 2021
Dopamine is a key regulator of glucose metabolism in the central nervous system. However, dopamine is also present in the periphery and may have direct effects on insulin-sensitive tissues.
Gabriela Tavares, Gabriela Tavares, Gabriela Tavares, Gabriela Tavares, Fatima. O. Martins, Bernardete. F. Melo, Paulo Matafome, Paulo Matafome, Paulo Matafome, Paulo Matafome, Silvia. V. Conde   +10 more
doaj   +1 more source

Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors [PDF]

, 2010
Methylphenidate (MP) and amphetamine (AMPH) are the most frequently prescribed medications for the treatment of attention-deficit/hyperactivity disorder (ADHD).
Bermeo, C., Grandy, David K., Rubinstein, Marcelo, Suchland, K. L., Thanos, P. K., Volkow, N. D., Wang, G. J.   +6 more
core   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

PLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito, Harumasa Takano, Ryosuke Arakawa, Hidehiko Takahashi, Fumitoshi Kodaka, Keisuke Takahata, Tsuyoshi Nogami, Masayuki Suzuki, Tetsuya Suhara   +8 more
doaj   +1 more source

Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells [PDF]

, 2018
While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents.
Chen, Andy, Fan, Yao, Jalali, Aydin, Li, Bai-Yan, Liu, Shengzhi, Minami, Kazumasa, Nakshatri, Harikrishna, Ogawa, Kazuhiko, Yokota, Hiroki   +8 more
core   +1 more source

D2 dopamine receptor subtype-mediated hyperactivity and amphetamine responses in a model of ADHD

Neurobiology of Disease, 2010
Low doses of psychostimulants produce beneficial behavioral effects in ADHD patients but the mechanisms underlying the response are not understood. Here we use the hyperactive mouse mutant coloboma to identify D2-like dopamine receptor subtypes that ...
Xueliang Fan, Ming Xu, Ellen J. Hess
doaj   +1 more source

Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit [PDF]

, 2009
The striatum, the principal input structure of the basal ganglia, is crucial to both motor control and learning. It receives convergent input from all over the neocortex, hippocampal formation, amygdala and thalamus, and is the primary recipient of ...
Alexander, Bar-Gad, Bauswein, Beiser, Belluardo, Berke, Berke, Bevan, Blackwell, Bolam, Bracci, Bracci, Brown, Burke, Buzsaki, Carrillo-Reid, Centonze, Cho, Czubayko, Dawson, Djurfeldt, Ferro, Frank, Fukai, Galan, Galarreta, Galvan, Gerfen, Glynn, Gonon, Gorelova, Groenewegen, Gurney, Humphries, Humphries, Humphries, Hurd, Ingham, Izhikevich, Izhikevich, Jaeger, Jahr, Kawaguchi, Kawaguchi, Kevin Gurney, Kirik, Kita, Koos, Koos, Kubota, Kwok, Lago-Fernandez, Mallet, Mark D. Humphries, Markram, McGeorge, Miller, Moyer, Newman, Newman, Nisenbaum, Nishikawa, Oorschot, O’Donnell, Pennartz, Plenz, Redgrave, Ric Wood, Richtand, Sandstrom, Schultz, Schwarting, Smith, Sullivan, Surmeier, Tang, Tateno, Taverna, Tepper, Traub, Tseng, Tunstall, Turner, Venton, Wang, Watts, Whishaw, Wickens, Wickens, Wilson, Yin, Zheng, Zhou   +92 more
core   +1 more source