Contralateral Spread of Asymmetrical Tremor in Parkinson's Disease
Abstract Background Parkinsonian tremor usually starts asymmetrically. The mid‐term prognosis of this lateralized tremor is unknown, as is the development of tremor in the contralateral arm. Objective To investigate the occurrence of contralateral tremor in the Parkinson's Progression Marker Initiative database, with data available for 7 years ...
Jacopo Pasquini +4 more
wiley +1 more source
Missed Insights for Earlier Management of Parkinson's Disease and the Value of Dopamine Transporter (DAT) Scans. [PDF]
Hafeez M, Eoff E, Wei J, Azhar G.
europepmc +1 more source
Is Dysphagia in Multiple System Atrophy Responsive to Levodopa? Results from a Retrospective Study
Abstract Background Dysphagia remains a major clinical concern in multiple system atrophy (MSA), and so far, lacks relevant treatment options. Objective To systematically assess levodopa‐responsiveness of dysphagia in MSA. Methods 19 MSA‐patients underwent endoscopic swallowing evaluation in Off‐ and On‐state, following an adapted FEES‐levodopa‐test ...
Florin Gandor +10 more
wiley +1 more source
Fully automatic categorical analysis of striatal subregions in dopamine transporter SPECT using a convolutional neural network. [PDF]
Buddenkotte T +4 more
europepmc +1 more source
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi +7 more
wiley +1 more source
Incentive Cocaine-Seeking Habits and Their Compulsive Manifestation Emerge After a Downregulation of the Dopamine Transporter in Astrocytes Across Functional Domains of the Striatum. [PDF]
Fouyssac M +4 more
europepmc +1 more source
Abstract Background Axial postural abnormalities (APAs) are common, disabling complications of Parkinson's disease (PD) with unclear pathophysiology. The presence of hyperactivity in multiple trunk muscles supports the use of botulinum toxin (BTA). However, its application is complex, due to the lack of standardized clinical and electrophysiological ...
Giacomo Argenziano +7 more
wiley +1 more source
Parkinson's disease gene, Synaptojanin1, dysregulates the surface maintenance of the dopamine transporter. [PDF]
Saenz J +6 more
europepmc +1 more source
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo +14 more
wiley +1 more source
Time for Clinical Dopamine Transporter Scans in Parkinsonism?: Not DAT Yet. [PDF]
Di Luca DG, Perlmutter JS.
europepmc +1 more source

