Results 311 to 320 of about 112,056 (332)
Some of the next articles are maybe not open access.
2016
Dementia with Lewy bodies (DLB) can be difficult to diagnose as it shares common features with both Alzheimer’s disease (AD) and Parkinson’s disease. Accurate differentiation from other types of dementia as well as early detection is essential to inform management and treatment.
Louise Colledge +2 more
openaire +1 more source
Dementia with Lewy bodies (DLB) can be difficult to diagnose as it shares common features with both Alzheimer’s disease (AD) and Parkinson’s disease. Accurate differentiation from other types of dementia as well as early detection is essential to inform management and treatment.
Louise Colledge +2 more
openaire +1 more source
Dopamine transporter mediated release of dopamine: Role of chloride
Journal of Neuroscience Research, 1994AbstractUsing a rapid (0.5 ml/min) flow rate superfusion system, the dopamine (DA) transporter mediated release of DA is further explored, and compared to the depolarization evoked release of DA in rat striatal synaptosomes preloaded with radioactive DA (3H‐DA).
M, Sitges, A, Reyes, L M, Chiu
openaire +2 more sources
The dopamine transporter: A crucial component regulating dopamine transmission
Movement Disorders, 1997AbstractThe dopamine system is implicated in the control of locomotion, cognition, and endocrine function, The relative contribution of the various dopamine‐related components is not well established mainly because drugs that target the dopaminergic system often lack selectivity.
M, Jaber, S, Jones, B, Giros, M G, Caron
openaire +2 more sources
Dopamine receptor and dopamine transporter in obesity: A meta‐analysis
Synapse, 2022Abstract The brain plays a major role in controlling the desire to eat. This meta‐analysis aimed to assess the association between dopamine receptor (DR) availability and dopamine transporter (DAT) availability, measured using positron emission tomography, and obesity.
Kyoungjune Pak +4 more
openaire +2 more sources
Molecular imaging of dopamine transporters
Ageing Research Reviews, 2016The dopamine transporter (DAT) is responsible for clearance of dopamine from the synaptic cleft after its release. Imaging DAT availability provides a measure of dopamine terminal function and a method for detecting the striatal dopamine terminal dysfunction present in idiopathic Parkinson's disease (PD) and atypical neurodegenerative parkinsonian ...
openaire +2 more sources
Dopamine reuptake and inhibitory mechanisms in human dopamine transporter
NatureThe dopamine transporter has a crucial role in regulation of dopaminergic neurotransmission by uptake of dopamine into neurons and contributes to the abuse potential of psychomotor stimulants1-3. Despite decades of study, the structure, substrate binding, conformational transitions and drug-binding poses of human dopamine transporter remain unknown ...
Yue Li +13 more
openaire +2 more sources
Dopamine transporter mutants selectively enhance MPP+ transport
Synapse, 1993AbstractMPP+ (1‐methyl‐4‐phenylpyridinium), a dopaminergic neurotoxin that provides the best available experimental model of Parkinson's disease, is selectively concentrated in dopamine neurons by the dopamine transporter (DAT). DAT also serves as a primary recognition site for cocaine. To help define selective molecular mechanisms by which MPP+ uptake
S, Kitayama, J B, Wang, G R, Uhl
openaire +2 more sources
Astroglial dopamine transport is mediated by norepinephrine transporter
Naunyn-Schmiedeberg's Archives of Pharmacology, 2002The aim of this study was to clarify the characteristics of the dopamine (DA) transport mechanism in cultured rat cortical astrocytes. Reverse transcription-polymerase chain reaction (RT-PCR) with DA transporter (DAT)-, norepinephrine (NE) transporter (NET)- and organic cation transporter 3 (OCT3)-specific primers demonstrated that rat cortical ...
Hiroshi, Takeda +2 more
openaire +2 more sources
Imaging Dopamine Transporters in Parkinson‘s Disease
Biomarkers in Medicine, 2010The dopamine transporter (DAT) is responsible for clearance of dopamine from the synaptic cleft after its release. Imaging DAT availability provides a measure of dopamine terminal function and a method for detecting striatal dopamine deficiency states present in idiopathic Parkinson's disease and atypical neurodegenerative Parkinsonian disorders such ...
openaire +3 more sources