Results 11 to 20 of about 392,840 (300)

The Cerebellar Dopaminergic System [PDF]

open access: yesFrontiers in Systems Neuroscience, 2021
In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive functions. Although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related ...
Paolo Flace   +11 more
doaj   +4 more sources

Dopaminergic therapy in aphasia [PDF]

open access: yesAphasiology, 2013
The dopaminergic system is involved in a wide range of cognitive functions including motor control, reward, memory, attention, problem-solving and learning. This has stimulated interest in investigating the potential of dopaminergic drugs as cognitive enhancers in aphasic patients.To discuss the evidence for the use of dopaminergic agents in patients ...
Gill, SK, Leff, AP
openaire   +4 more sources

Polydopamine Nanoparticle‐Mediated Dopaminergic Immunoregulation in Colitis

open access: yesAdvanced Science, 2022
Despite immunosuppression is critical for reducing immune overactivation, existing immunosuppressive agents are largely restricted by low inhibition efficiencies and unpredictable off‐target toxicities.
Juanjuan Li   +6 more
doaj   +1 more source

Venoms as an adjunctive therapy for Parkinson’s disease: where are we now and where are we going?

open access: yesFuture Science OA, 2021
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in the aging population. Crucially, neurodegeneration of dopaminergic neurons in PD is associated with chronic inflammation and glial activation.
Parisa Gazerani
doaj   +1 more source

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2020
Purpose This joint practice guideline or procedure standard was developed collaboratively by the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
S. Morbelli   +27 more
semanticscholar   +1 more source

Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I.   +3 more
doaj   +1 more source

Adult subventricular zone neural stem cells as a potential source of dopaminergic replacement neurons

open access: yesFrontiers in Neuroscience, 2014
Clinical trials engrafting human fetal ventral mesencephalic tissue have demonstrated, in principle, that cell replacement therapy provides substantial long-lasting improvement of motor impairments generated by Parkinson’s Disease.
John eCave   +5 more
doaj   +1 more source

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]

open access: yes, 2018
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro   +7 more
core   +3 more sources

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]

open access: yes, 2014
Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana   +75 more
core   +5 more sources

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

open access: yesFrontiers in Neurology, 2019
Background: The actions of caffeine as an antagonist of adenosine receptors have been extensively studied, and there is no doubt that both daily and sporadic dietary consumption of caffeine has substantial biological effects on the nervous system ...
Karl B. Alstadhaug   +3 more
doaj   +1 more source

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