Results 11 to 20 of about 243,277 (347)

The Cerebellar Dopaminergic System [PDF]

Frontiers in Systems Neuroscience, 2021
In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive functions. Although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related ...
Paolo Flace, Paolo Livrea, Gianpaolo Antonio Basile, Diana Galletta, Antonella Bizzoca, Gianfranco Gennarini, Salvatore Bertino, Jacopo Junio Valerio Branca, Massimo Gulisano, Simona Bianconi, Alessia Bramanti, Giuseppe Anastasi   +11 more
doaj   +4 more sources

Dopaminergic therapy in aphasia [PDF]

Aphasiology, 2013
The dopaminergic system is involved in a wide range of cognitive functions including motor control, reward, memory, attention, problem-solving and learning. This has stimulated interest in investigating the potential of dopaminergic drugs as cognitive enhancers in aphasic patients.To discuss the evidence for the use of dopaminergic agents in patients ...
Gill, SK, Leff, AP
openaire   +4 more sources

Next-generation GRAB sensors for monitoring dopaminergic activity in vivo

Nature Methods, 2020
Dopamine (DA) plays a critical role in the brain, and the ability to directly measure dopaminergic activity is essential for understanding its physiological functions. We therefore developed red fluorescent G-protein-coupled receptor-activation-based DA (
Fangmiao Sun, Jingheng Zhou, Bing Dai, Tongrui Qian, Jianzhi Zeng, Xuelin Li, Yizhou Zhuo, Yajun Zhang, Yipan Wang, Cheng Qian, Ke Tan, Jiesi Feng, Hui Dong, Dayu Lin, Guohong Cui, Yulong Li   +15 more
semanticscholar   +1 more source

Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction

International Journal of Molecular Sciences, 2021
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia, responsible for the onset of several long-term complications. Recent evidence suggests that cognitive dysfunction represents an emerging complication of DM, but the ...
F. Pignalosa, Antonella Desiderio, P. Mirra, C. Nigro, Giuseppe Perruolo, L. Ulianich, P. Formisano, F. Beguinot, C. Miele, R. Napoli, F. Fiory   +10 more
semanticscholar   +1 more source

Stress and the dopaminergic reward system

Experimental and Molecular Medicine, 2020
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the mesolimbic dopamine system.
J. Baik
semanticscholar   +1 more source

Pre-clinical study of induced pluripotent stem cell-derived dopaminergic progenitor cells for Parkinson’s disease

Nature Communications, 2020
Induced pluripotent stem cell (iPSC)-derived dopaminergic (DA) neurons are an expected source for cell-based therapies for Parkinson’s disease (PD).
D. Doi, Hiroaki Magotani, Tetsuhiro Kikuchi, Megumi Ikeda, Satoe Hiramatsu, Kenji Yoshida, Naoki Amano, Masaki Nomura, Masafumi Umekage, A. Morizane, J. Takahashi   +10 more
semanticscholar   +1 more source

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0

European Journal of Nuclear Medicine and Molecular Imaging, 2020
Purpose This joint practice guideline or procedure standard was developed collaboratively by the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
S. Morbelli, G. Esposito, J. Arbizu, H. Barthel, R. Boellaard, N. Bohnen, D. Brooks, J. Darcourt, J. Dickson, David Douglas, A. Drzezga, J. Dubroff, O. Ekmekcioglu, V. Garibotto, P. Herscovitch, P. Kuo, A. Lammertsma, S. Pappatà, I. Peñuelas, J. Seibyl, F. Semah, L. Tossici-Bolt, E. M. van de Giessen, K. Van Laere, A. Varrone, Michele Wanner, G. Zubal, I. Law   +27 more
semanticscholar   +1 more source

Dopaminergic symptoms in migraine [PDF]

Neurological Sciences, 2013
Migraine pain is often preceded, accompanied and followed by dopaminergic symptoms (premonitory yawning and somnolence, accompanying nausea and vomiting, postdromal somnolence, euphoria and polyuria). After reviewing evidence from pharmacological, biochemical, genetic and animal experimental studies on the relationship between dopamine and migraine ...
Barbanti, Piero, Fofi, L., Aurilia, C., Egeo, G.   +3 more
openaire   +3 more sources

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Science Translational Medicine, 2018
Oral treatment with a brain-penetrant NLRP3 inhibitor has protective effects in preclinical models of Parkinson’s disease. Systemic inflammasome inhibitor for Parkinson’s disease Brain accumulation of misfolded α-synuclein, progressive loss of ...
R. Gordon, Eduardo A. Albornoz, Daniel C. Christie, Monica R. Langley, Vinod Kumar, S. Mantovani, A. Robertson, M. Butler, D. Rowe, L. O’Neill, A. Kanthasamy, K. Schroder, M. Cooper, T. Woodruff   +13 more
semanticscholar   +1 more source

Suppression of a single pair of mushroom body output neurons in Drosophila triggers aversive associations

FEBS Open Bio, 2017
Memory includes the processes of acquisition, consolidation and retrieval. In the study of aversive olfactory memory in Drosophila melanogaster, flies are first exposed to an odor (conditioned stimulus, CS+) that is associated with an electric shock ...
Yutaro Ueoka, Makoto Hiroi, Takashi Abe, Tetsuya Tabata   +3 more
doaj   +1 more source