Deficient reinforcement learning in medial frontal cortex as a model of dopamine-related motivational deficits in ADHD [PDF]
A
Barke, Edmund +3 more
core +2 more sources
Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration
Male courtship in Drosophila melanogaster is a sexually dimorphic innate behavior that is hardwired in the nervous system. Understanding the neural mechanism of courtship behavior requires the anatomical and functional characterization of all the neurons
Shreyas Jois +3 more
doaj +1 more source
Wnt/β-catenin signaling contributes to patterning, proliferation, and differentiation throughout vertebrate neural development. Wnt/β-catenin signaling is important for mammalian midbrain dopaminergic neurogenesis, while little is known about its role in
Markus Westphal +4 more
doaj +1 more source
Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes
Serotonin (5-hydroxytryptamine, 5-HT) is a phylogenetically conserved modulator of numerous aspects of neural functions. Serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain ...
Toshiyuki Fujita +6 more
doaj +1 more source
The competitive NMDA antagonist CPP protects substantia nigra neurons from MPTP-induced degeneration in primates [PDF]
Degeneration of nigrostriatal dopaminergic neurons is the primary histopathological feature of Parkinson's disease. The neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induces a neurological syndrome in man and non-human primates very ...
Burg, M. +7 more
core +1 more source
Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans. [PDF]
Disruption of dopamine homeostasis may lead to dopaminergic neuron degeneration, a proposed explanation for the specific vulnerability of dopaminergic neurons in Parkinson's disease. While expression of human alpha-synuclein in C.
Pengxiu Cao +6 more
doaj +1 more source
Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat [PDF]
Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR ...
Jahn, Graciela Alma +4 more
core +1 more source
Locus coeruleus and dopaminergic consolidation of everyday memory
The retention of episodic-like memory is enhanced, in humans and animals, when something novel happens shortly before or after encoding. Using an everyday memory task in mice, we sought the neurons mediating this dopamine-dependent novelty effect ...
T. Takeuchi +10 more
semanticscholar +1 more source
The increased risk and prevalence of lacunar stroke and Parkinson's disease makes the search for better experimental models an important requirement for translational research.
Vilma Consuelo Muñeton-Gomez +10 more
doaj +1 more source
Dopaminergic therapy in aphasia [PDF]
The dopaminergic system is involved in a wide range of cognitive functions including motor control, reward, memory, attention, problem-solving and learning. This has stimulated interest in investigating the potential of dopaminergic drugs as cognitive enhancers in aphasic patients.To discuss the evidence for the use of dopaminergic agents in patients ...
Gill, SK, Leff, AP
openaire +3 more sources

