Results 21 to 30 of about 160,871 (266)

Suppression of a single pair of mushroom body output neurons in Drosophila triggers aversive associations

FEBS Open Bio, 2017
Memory includes the processes of acquisition, consolidation and retrieval. In the study of aversive olfactory memory in Drosophila melanogaster, flies are first exposed to an odor (conditioned stimulus, CS+) that is associated with an electric shock ...
Yutaro Ueoka, Makoto Hiroi, Takashi Abe, Tetsuya Tabata   +3 more
doaj   +1 more source

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

Stem Cell Reports, 2017
Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD).
Daniela Lehnen, Serena Barral, Tiago Cardoso, Shane Grealish, Andreas Heuer, Andrej Smiyakin, Agnete Kirkeby, Jutta Kollet, Harold Cremer, Malin Parmar, Andreas Bosio, Sebastian Knöbel   +11 more
doaj   +1 more source

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Frontiers in Neurology, 2019
Background: The actions of caffeine as an antagonist of adenosine receptors have been extensively studied, and there is no doubt that both daily and sporadic dietary consumption of caffeine has substantial biological effects on the nervous system ...
Karl B. Alstadhaug, Karl B. Alstadhaug, Anna P. Andreou, Anna P. Andreou   +3 more
doaj   +1 more source

Evaluation of the Association Between Serum Levels of Testosterone and Prolactin With 6- Hydroxydopamine- Induced Parkinsonism in Male Rats

Basic and Clinical Neuroscience, 2021
Introduction: Parkinson’s Disease (PD) associates with changes in sex hormones; however, it remains unknown whether this is either a cause for or a result of the disease.
Roghaieh Razaghi, Hossein Piri, Hanieh Jafari, Nafiseh Rastgoo, Mohammad Ali Hosseini, Hashem Haghdoost – Yazdi   +5 more
doaj  

Adult subventricular zone neural stem cells as a potential source of dopaminergic replacement neurons

Frontiers in Neuroscience, 2014
Clinical trials engrafting human fetal ventral mesencephalic tissue have demonstrated, in principle, that cell replacement therapy provides substantial long-lasting improvement of motor impairments generated by Parkinson’s Disease.
John eCave, John eCave, Meng eWang, Meng eWang, Harriet eBaker, Harriet eBaker   +5 more
doaj   +1 more source

Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. [PDF]

PLoS ONE, 2013
Dopaminergic differentiation of embryonic stem cells (ESCs) gains more and more attention worldwide owing to its potential use for neurorestorative therapy for the treatment of Parkinson's disease.
Na Ni, Yaohua Hu, Huixia Ren, Chuanming Luo, Peng Li, Jian-Bo Wan, Huanxing Su   +6 more
doaj   +1 more source

The BE (2)-M17 cell line has a better dopaminergic phenotype than the traditionally used for Parkinson´s research SH-SY5Y, which is mostly serotonergic

IBRO Neuroscience Reports, 2022
SH-SY5Y is a cell line derived from human neuroblastoma. It is one of the most widely used in vitro models to study Parkinson’s disease. Surprisingly, it has been found that it does not develop a dopaminergic phenotype after differentiation, questioning ...
Angel Carvajal-Oliveros, Maritere Uriostegui-Arcos, Mario Zurita, Erika I. Melchy-Perez, Verónica Narváez-Padilla, Enrique Reynaud   +5 more
doaj   +1 more source

Dopaminergic therapy in aphasia [PDF]

Aphasiology, 2013
The dopaminergic system is involved in a wide range of cognitive functions including motor control, reward, memory, attention, problem-solving and learning. This has stimulated interest in investigating the potential of dopaminergic drugs as cognitive enhancers in aphasic patients.To discuss the evidence for the use of dopaminergic agents in patients ...
Gill, SK, Leff, AP
openaire   +3 more sources

Organotypic mouse brain slices: low-cost “ring-inserts” to study cholinergic and dopaminergic neurons with live cell imaging with an emphasis on calcium imaging [PDF]

Biofunctional Materials
Organotypic brain slices preserve the complex 3D cellular structure and are the most potent ex vivo cultures, similar to in vivo conditions. However, their use is limited because of expensive membrane inserts and because the slices cannot be used for ...
Alessa Gern, Patricia Lehmann, Judith Schäfer, Christian Humpel   +3 more
doaj   +1 more source

A sex difference in mouse dopaminergic projections from the midbrain to basolateral amygdala

Biology of Sex Differences, 2022
Highlights Cell-type specific labeling of VTA-to-BLA dopaminergic axons and synaptic boutons in mice The intensity of dopaminergic innervation in BLA is intermediate between those in PFC and NAC Dopaminergic axon density in BLA and the size of BLA are ...
Matthew T. C. Manion, Erica R. Glasper, Kuan Hong Wang   +2 more
doaj   +1 more source