Results 11 to 20 of about 160,871 (266)

The Cerebellar Dopaminergic System [PDF]

open access: yesFrontiers in Systems Neuroscience, 2021
In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive functions. Although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related ...
Paolo Flace   +11 more
doaj   +4 more sources

Dopaminergic symptoms in migraine [PDF]

open access: yesNeurological Sciences, 2013
Migraine pain is often preceded, accompanied and followed by dopaminergic symptoms (premonitory yawning and somnolence, accompanying nausea and vomiting, postdromal somnolence, euphoria and polyuria). After reviewing evidence from pharmacological, biochemical, genetic and animal experimental studies on the relationship between dopamine and migraine ...
Barbanti, Piero   +3 more
openaire   +3 more sources

THE DOPAMINERGIC SYSTEM IN HYPERTENSION

open access: yesClinical and Experimental Hypertension, 2001
Dopamine exerts cardiovascular and renal actions mediated through interaction with specific dopamine receptors. Dopamine receptors are cell surface receptors coupled to G-proteins and classified into two main super families based on biochemical, pharmacological and molecular characteristics. The dopamine D1-like receptor super family includes D1 and D5
AMENTA, Francesco   +4 more
openaire   +3 more sources

Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes

open access: yesFrontiers in Physiology, 2022
Serotonin (5-hydroxytryptamine, 5-HT) is a phylogenetically conserved modulator of numerous aspects of neural functions. Serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain ...
Toshiyuki Fujita   +6 more
doaj   +1 more source

Neural differentiation of transplanted neural stem cells in a rat model of striatal lacunar infarction: light and electron microscopic observations

open access: yesFrontiers in Cellular Neuroscience, 2012
The increased risk and prevalence of lacunar stroke and Parkinson's disease makes the search for better experimental models an important requirement for translational research.
Vilma Consuelo Muñeton-Gomez   +10 more
doaj   +1 more source

Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2010
Disruption of dopamine homeostasis may lead to dopaminergic neuron degeneration, a proposed explanation for the specific vulnerability of dopaminergic neurons in Parkinson's disease. While expression of human alpha-synuclein in C.
Pengxiu Cao   +6 more
doaj   +1 more source

Levosulpiride-induced neurological adverse effects: A prospective study from a tertiary care center

open access: yesAnnals of Indian Academy of Neurology, 2020
Background: Levosulpiride (LS) is a prokinetic drug increasingly used for the gastric motility disorders. Despite its common use for the gastric motility disorder, the tendency to cause parkinsonism and acute dystonias are under-recognized as the major ...
Jacob Joe
doaj   +1 more source

Electrical and Ca2+ signaling in dendritic spines of substantia nigra dopaminergic neurons

open access: yeseLife, 2016
Little is known about the density and function of dendritic spines on midbrain dopamine neurons, or the relative contribution of spine and shaft synapses to excitability.
Travis A Hage, Yujie Sun, Zayd M Khaliq
doaj   +1 more source

Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

open access: yesMolecular Brain, 2021
Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial ...
Mutsumi Yokota   +7 more
doaj   +1 more source

Endoplasmic Reticulum Stress Is Associated with the Mesencephalic Dopaminergic Neuron Injury in Stressed Rats

open access: yesAnalytical Cellular Pathology, 2021
An increasing number of people are in a state of stress due to social and psychological pressures, which may result in mental disorders. Previous studies indicated that mesencephalic dopaminergic neurons are associated with not only reward-related ...
Shiba Niu   +7 more
doaj   +1 more source

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