Results 21 to 30 of about 392,840 (300)
CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1. [PDF]
, 2017 Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin αIIb. Although CIB1 has been shown to interact with multiple proteins, its biological function in the brain
Choi, Eui-Ju +8 more
core +4 more sources
Frontiers in Cellular Neuroscience, 2012 The increased risk and prevalence of lacunar stroke and Parkinson's disease makes the search for better experimental models an important requirement for translational research.
Vilma Consuelo Muñeton-Gomez +10 more
doaj +1 more source
Scientific Reports, 2022 Wnt/β-catenin signaling contributes to patterning, proliferation, and differentiation throughout vertebrate neural development. Wnt/β-catenin signaling is important for mammalian midbrain dopaminergic neurogenesis, while little is known about its role in
Markus Westphal +4 more
doaj +1 more source
Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes
Frontiers in Physiology, 2022 Serotonin (5-hydroxytryptamine, 5-HT) is a phylogenetically conserved modulator of numerous aspects of neural functions. Serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain ...
Toshiyuki Fujita +6 more
doaj +1 more source
Alpha-synuclein disrupted dopamine homeostasis leads to dopaminergic neuron degeneration in Caenorhabditis elegans. [PDF]
PLoS ONE, 2010 Disruption of dopamine homeostasis may lead to dopaminergic neuron degeneration, a proposed explanation for the specific vulnerability of dopaminergic neurons in Parkinson's disease. While expression of human alpha-synuclein in C.
Pengxiu Cao +6 more
doaj +1 more source
Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]
, 2011 Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico +6 more
core +2 more sources
THE DOPAMINERGIC SYSTEM IN HYPERTENSION
Clinical and Experimental Hypertension, 2001 Dopamine exerts cardiovascular and renal actions mediated through interaction with specific dopamine receptors. Dopamine receptors are cell surface receptors coupled to G-proteins and classified into two main super families based on biochemical, pharmacological and molecular characteristics. The dopamine D1-like receptor super family includes D1 and D5
AMENTA, Francesco +4 more
openaire +4 more sources
Molecular Brain, 2021 Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial ...
Mutsumi Yokota +7 more
doaj +1 more source
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
, 2018 Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
Locus coeruleus and dopaminergic consolidation of everyday memory
Nature, 2016 The retention of episodic-like memory is enhanced, in humans and animals, when something novel happens shortly before or after encoding. Using an everyday memory task in mice, we sought the neurons mediating this dopamine-dependent novelty effect ...
T. Takeuchi +10 more
semanticscholar +1 more source