Results 21 to 30 of about 398,911 (393)

Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion. A possible compensatory mechanism in Parkinson’s disease

Frontiers in Systems Neuroscience, 2011
The onset of Parkinson's disease (PD) is characterized by focal motor features in one body part, which are usually correlated with greater dopaminergic depletion in the contralateral posterior putamen. The role of dopamine (DA) hemispheric differences in
Javier eBlesa, Javier eBlesa, Carlos eJuri, Carlos eJuri, Miguel Ángel eGarcía-Cabezas, Miguel Ángel eGarcía-Cabezas, Rebeca eAdánez, Rebeca eAdánez, Miguel Ángel eSánchez-González, Miguel Ángel eSánchez-González, Carmen eCavada, Carmen eCavada, José A. eObeso, José A. eObeso, José A. eObeso   +14 more
doaj   +1 more source

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]

, 2014
Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana, A Moszczynska, A Priyadarshi, Alexander Holmes, Anton Gartner, AT Allen, B Giros, C Boucheix, C Boucheix, C Boucheix, C Klein, C Missale, CD Dunn, CH Lai, D Vallone, DB Calne, DL Chase, E Rubinstein, E Rubinstein, EA Bolan, ER Sawin, ES Calipari, FJ Lee, FJ Lee, GC Cotzias, GR Uhl, H Maharaj, H Moribe, H Moribe, HP Rang, J Bove, J Sulston, JE Galvin, JG White, JM Beaulieu, JW Langston, K Jellinger, K Strange, K Tieu, KF Tipton, Kim A. Caldwell, L Carvelli, LD Jayanthi, M Santiago, MJ Ferris, MJ LaVoie, MJ Zigmond, ML Toth, MS Szczypka, MW Davis, MY Chang, N Chen, Neda Masoudi, O Thompson, P Seeman, P Seeman, P Sokoloff, Pablo Ibanez-Cruceyra, PW McDonald, QY Zhou, R Andrew, R Nass, R Nass, RM Kostrzewa, RR Gainetdinov, S Brenner, S Cao, S Charrin, S Fahn, S Fahn, S Thaminy, Sarah-Lena Offenburger, TN Chase, W Birkmayer, WA Cass, Y Glinka   +75 more
core   +5 more sources

Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration

Frontiers in Physiology, 2018
Male courtship in Drosophila melanogaster is a sexually dimorphic innate behavior that is hardwired in the nervous system. Understanding the neural mechanism of courtship behavior requires the anatomical and functional characterization of all the neurons
Shreyas Jois, Yick Bun Chan, Maria Paz Fernandez, Adelaine Kwun-Wai Leung   +3 more
doaj   +1 more source

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]

, 2018
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro, García Domínguez, Irene, García Revilla, Juan, Martínez de Pablos, Rocío, Roca Ceballos, María Angustias, Santiago Pavón, Martiniano, Venero Recio, José Luis, Veselá, Karolina   +7 more
core   +3 more sources

Neural differentiation of transplanted neural stem cells in a rat model of striatal lacunar infarction: light and electron microscopic observations

Frontiers in Cellular Neuroscience, 2012
The increased risk and prevalence of lacunar stroke and Parkinson's disease makes the search for better experimental models an important requirement for translational research.
Vilma Consuelo Muñeton-Gomez, Ernesto eDoncel-Perez, Ana Patricia eFernandez, Julia eSerrano Masa, Andrea ePozo-Rodrigalvarez, Lara eVellosillo-Huerta, Julian eScott Taylor, Gloria Patricia eCardona-Gomez, Manuel eNieto-Sampedro, Manuel eNieto-Sampedro, Ricardo eMartinez-Murillo   +10 more
doaj   +1 more source

THE DOPAMINERGIC SYSTEM IN HYPERTENSION

Clinical and Experimental Hypertension, 2001
Dopamine exerts cardiovascular and renal actions mediated through interaction with specific dopamine receptors. Dopamine receptors are cell surface receptors coupled to G-proteins and classified into two main super families based on biochemical, pharmacological and molecular characteristics. The dopamine D1-like receptor super family includes D1 and D5
AMENTA, Francesco, TAYEBATI, Seyed Khosrow, RICCI A., ROSSODIVITA I., AVOLA R.   +4 more
openaire   +3 more sources

CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1. [PDF]

, 2017
Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin αIIb. Although CIB1 has been shown to interact with multiple proteins, its biological function in the brain
Choi, Eui-Ju, Kang, Seongman, Kim, Yeonsil, Kim, Young Mok, Naik, Ulhas P., Parise, Leslie V., Sun, Woong, Yang, Hyun-Suk, Yoon, Kyoung Wan   +8 more
core   +4 more sources

Wnt/β-catenin signaling promotes neurogenesis in the diencephalospinal dopaminergic system of embryonic zebrafish

Scientific Reports, 2022
Wnt/β-catenin signaling contributes to patterning, proliferation, and differentiation throughout vertebrate neural development. Wnt/β-catenin signaling is important for mammalian midbrain dopaminergic neurogenesis, while little is known about its role in
Markus Westphal, Paolo Panza, Edda Kastenhuber, Johanna Wehrle, Wolfgang Driever   +4 more
doaj   +1 more source

Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes

Frontiers in Physiology, 2022
Serotonin (5-hydroxytryptamine, 5-HT) is a phylogenetically conserved modulator of numerous aspects of neural functions. Serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain ...
Toshiyuki Fujita, Naoya Aoki, Chihiro Mori, Shouta Serizawa, Fumiko Kihara-Negishi, Koichi J. Homma, Shinji Yamaguchi   +6 more
doaj   +1 more source

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Frontiers in Neurology, 2019
Background: The actions of caffeine as an antagonist of adenosine receptors have been extensively studied, and there is no doubt that both daily and sporadic dietary consumption of caffeine has substantial biological effects on the nervous system ...
Karl B. Alstadhaug, Karl B. Alstadhaug, Anna P. Andreou, Anna P. Andreou   +3 more
doaj   +1 more source