Results 31 to 40 of about 392,840 (300)

Non-Dopaminergic Therapies

Journal of Parkinson’s Disease, 2018
Currently all aspects of Parkinson’s disease (PD) treatment are less than ideal and would benefit from new interventions. We focus on problems associated with brain neurotransmitters amenable to more specific subreceptor and temporal manipulation.
Nicolaas I. Bohnen, John G. Nutt
openaire   +4 more sources

Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration

Frontiers in Physiology, 2018
Male courtship in Drosophila melanogaster is a sexually dimorphic innate behavior that is hardwired in the nervous system. Understanding the neural mechanism of courtship behavior requires the anatomical and functional characterization of all the neurons
Shreyas Jois, Yick Bun Chan, Maria Paz Fernandez, Adelaine Kwun-Wai Leung   +3 more
doaj   +1 more source

Dopaminergic Retinal Cell Loss and Visual Dysfunction in Parkinson Disease

Annals of Neurology, 2020
Considering the demonstrated implication of the retina in Parkinson disease (PD) pathology and the importance of dopaminergic cells in this tissue, we aimed to analyze the state of the dopaminergic amacrine cells and some of their main postsynaptic ...
Isabel Ortuño-Lizarán, Xavier Sánchez-Sáez, P. Lax, G. Serrano, T. Beach, C. Adler, N. Cuenca   +6 more
semanticscholar   +1 more source

Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion. A possible compensatory mechanism in Parkinson’s disease

Frontiers in Systems Neuroscience, 2011
The onset of Parkinson's disease (PD) is characterized by focal motor features in one body part, which are usually correlated with greater dopaminergic depletion in the contralateral posterior putamen. The role of dopamine (DA) hemispheric differences in
Javier eBlesa, Javier eBlesa, Carlos eJuri, Carlos eJuri, Miguel Ángel eGarcía-Cabezas, Miguel Ángel eGarcía-Cabezas, Rebeca eAdánez, Rebeca eAdánez, Miguel Ángel eSánchez-González, Miguel Ángel eSánchez-González, Carmen eCavada, Carmen eCavada, José A. eObeso, José A. eObeso, José A. eObeso   +14 more
doaj   +1 more source

Endoplasmic Reticulum Stress Is Associated with the Mesencephalic Dopaminergic Neuron Injury in Stressed Rats

Analytical Cellular Pathology, 2021
An increasing number of people are in a state of stress due to social and psychological pressures, which may result in mental disorders. Previous studies indicated that mesencephalic dopaminergic neurons are associated with not only reward-related ...
Shiba Niu, Weibo Shi, Yingmin Li, Shanyong Yi, Yang Li, Xia Liu, Bin Cong, Guanglong He   +7 more
doaj   +1 more source

Deficient reinforcement learning in medial frontal cortex as a model of dopamine-related motivational deficits in ADHD [PDF]

, 2013
A
Barke, Edmund, Silvetti, Massimo, Verguts, Tom, Wiersema, Roeljan   +3 more
core   +2 more sources

Suppression of a single pair of mushroom body output neurons in Drosophila triggers aversive associations

FEBS Open Bio, 2017
Memory includes the processes of acquisition, consolidation and retrieval. In the study of aversive olfactory memory in Drosophila melanogaster, flies are first exposed to an odor (conditioned stimulus, CS+) that is associated with an electric shock ...
Yutaro Ueoka, Makoto Hiroi, Takashi Abe, Tetsuya Tabata   +3 more
doaj   +1 more source

Altered expression patterns of inflammation-associated and trophic molecules in substantia nigra and striatum brain samples from Parkinson’s disease, incidental Lewy body disease and normal control cases

Frontiers in Neuroscience, 2016
Evidence of inflammation has been consistently associated with pathology in Parkinson’s disease (PD)-affected brains, and has been suggested as a causative factor.
Douglas Gordon Walker, Lih-Fen eLue, Geidy eSerrano, Thomas Gerald Beach, Lucia eSue, Charles H. Adler, John eCaviness   +6 more
doaj   +1 more source

Active inference, evidence accumulation, and the urn task [PDF]

, 2015
Deciding how much evidence to accumulate before making a decision is a problem we and other animals often face, but one that is not completely understood.
Attias H., Beal M. J., Karl Friston, Michael Moutoussis, Philipp Schwartenbeck, Raymond J. Dolan, Schwartenbeck P., Thomas H. B. FitzGerald   +7 more
core   +1 more source

Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons

Frontiers in Neural Circuits, 2019
Dopaminergic and serotonergic neurons modulate and control processes ranging from reward signaling to regulation of motor outputs. Further, dysfunction of these neurons is involved in both degenerative and psychiatric disorders.
Alexandra Krol, Violeta G. Lopez-Huerta, Violeta G. Lopez-Huerta, Violeta G. Lopez-Huerta, Taylor E. C. Corey, Karl Deisseroth, Karl Deisseroth, Karl Deisseroth, Jonathan T. Ting, Jonathan T. Ting, Guoping Feng, Guoping Feng   +11 more
doaj   +1 more source