Results 41 to 50 of about 398,911 (393)

Dopaminergic symptoms in migraine [PDF]

open access: yesNeurological Sciences, 2013
Migraine pain is often preceded, accompanied and followed by dopaminergic symptoms (premonitory yawning and somnolence, accompanying nausea and vomiting, postdromal somnolence, euphoria and polyuria). After reviewing evidence from pharmacological, biochemical, genetic and animal experimental studies on the relationship between dopamine and migraine ...
Piero, Barbanti   +3 more
openaire   +2 more sources

Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]

open access: yes, 2011
Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico   +6 more
core   +2 more sources

Altered expression patterns of inflammation-associated and trophic molecules in substantia nigra and striatum brain samples from Parkinson’s disease, incidental Lewy body disease and normal control cases

open access: yesFrontiers in Neuroscience, 2016
Evidence of inflammation has been consistently associated with pathology in Parkinson’s disease (PD)-affected brains, and has been suggested as a causative factor.
Douglas Gordon Walker   +6 more
doaj   +1 more source

Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons

open access: yesFrontiers in Neural Circuits, 2019
Dopaminergic and serotonergic neurons modulate and control processes ranging from reward signaling to regulation of motor outputs. Further, dysfunction of these neurons is involved in both degenerative and psychiatric disorders.
Alexandra Krol   +11 more
doaj   +1 more source

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

open access: yes, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano   +3 more
core   +2 more sources

Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. [PDF]

open access: yesPLoS ONE, 2013
Dopaminergic differentiation of embryonic stem cells (ESCs) gains more and more attention worldwide owing to its potential use for neurorestorative therapy for the treatment of Parkinson's disease.
Na Ni   +6 more
doaj   +1 more source

The Dopaminergic Midbrain Encodes the Expected Certainty about Desired Outcomes [PDF]

open access: yes, 2014
Dopamine plays a key role in learning; however, its exact function in decision making and choice remains unclear. Recently, we proposed a generic model based on active (Bayesian) inference wherein dopamine encodes the precision of beliefs about optimal ...
Dolan, Ray   +4 more
core   +2 more sources

Electrical and Ca2+ signaling in dendritic spines of substantia nigra dopaminergic neurons

open access: yeseLife, 2016
Little is known about the density and function of dendritic spines on midbrain dopamine neurons, or the relative contribution of spine and shaft synapses to excitability.
Travis A Hage, Yujie Sun, Zayd M Khaliq
doaj   +1 more source

Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.

open access: yes, 2019
Parkinson's disease (PD) is characterized by the presence of α-synuclein aggregates known as Lewy bodies and Lewy neurites, whose formation is linked to disease development. The causal relation between α-synuclein aggregates and PD is not well understood.
Anichtchik, O.   +12 more
core   +1 more source

Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]

open access: yes, 2018
Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco   +3 more
core   +1 more source

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