Results 41 to 50 of about 240,256 (373)
A sex difference in mouse dopaminergic projections from the midbrain to basolateral amygdala
Biology of Sex Differences, 2022 Highlights Cell-type specific labeling of VTA-to-BLA dopaminergic axons and synaptic boutons in mice The intensity of dopaminergic innervation in BLA is intermediate between those in PFC and NAC Dopaminergic axon density in BLA and the size of BLA are ...
Matthew T. C. Manion +2 more
doaj +1 more source
Representation learning with reward prediction errors [PDF]
arXiv, 2021 The Reward Prediction Error hypothesis proposes that phasic activity in the midbrain dopaminergic system reflects prediction errors needed for learning in reinforcement learning. Besides the well-documented association between dopamine and reward processing, dopamine is implicated in a variety of functions without a clear relationship to reward ...
arxiv
Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. [PDF]
PLoS ONE, 2013 Dopaminergic differentiation of embryonic stem cells (ESCs) gains more and more attention worldwide owing to its potential use for neurorestorative therapy for the treatment of Parkinson's disease.
Na Ni +6 more
doaj +1 more source
Can linking the recall system to addiction enable a better understanding of the dopaminergic pathway? [PDF]
arXiv, 2022 Human addiction, as a learned behaviour, has and is constantly being treated psychologically, with specific and timely interventions from Neuroscience. We endorse that human addiction can receive further boost as regards treatment, when we firmly understand how it works from a quantum scale. This is majorly because the dopaminergic pathway (DP) that is
arxiv
Dopaminergic Mechanisms in Adhd
Pediatric Neurology Briefs, 2014 Investigators at Addenbrooke's Hospital, University of Cambridge, UK, and centers in Germany and France examined the neural mechanisms underlying attention deficits associated with ADHD and their reversal with a single dose of methylphenidate (MPH).
John Millichap, J. G. Millichap
openaire +4 more sources
Stem Cell Reports, 2017 Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD).
Daniela Lehnen +11 more
doaj +1 more source
Postnatal functional inactivation of the ventral subiculum enhances dopaminergic responses in the core part of the nucleus accumbens following ketamine injection in adult rats [PDF]
, 2020 For almost two decades schizophrenia has been considered to be a functional disconnection disorder. This functional disconnectivity between several brain regions could have a neurodevelopmental origin. Various approaches suggest the ventral subiculum (SUB) is a particular target region for neurodevelopemental disturbances in schizophrenia.
arxiv +1 more source
Journal of Neuroscience, 1997 Subanesthetic doses of ketamine, a noncompetitive NMDA receptor antagonist, impair prefrontal cortex (PFC) function in the rat and produce symptoms in humans similar to those observed in schizophrenia and dissociative states, including impaired ...
B. Moghaddam +3 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Parkinson’s disease is characterized by the accumulation of amyloid deposits in dopaminergic neurons, mainly composed of the protein α-synuclein.
Jordi Pujols +17 more
semanticscholar +1 more source
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu +12 more
wiley +1 more source