Results 151 to 160 of about 65,347 (261)

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source

A LNK-CBL-HNRPA2B1-GPX4 signaling axis mediates dopaminergic neuron vulnerability to ferroptosis in Parkinson's disease. [PDF]

Redox Biol
Liu Z, Wang R, Shen M, Lan X, Yan W, Wang S, Jiang M, Li R, Zhao J, Wang Q, Xv X, Zhou J, Pan X, Li W, Gong W, Qian L.   +15 more
europepmc   +1 more source

The Incidence of Sensorineural Hearing Loss Diagnoses in People with and without Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and sensorineural hearing loss (SNHL) are both prevalent conditions among older adults. Although increasing number of studies have investigated SNHL as a risk factor for PD, it is not well known how diagnosed PD affects the likelihood of SNHL diagnosis.
Kaisa Hokkinen, Aarno Dietz, Pasi Lampela, Sirpa Hartikainen, Anna‐Maija Tolppanen   +4 more
wiley   +1 more source

Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa remains the most effective pharmacological treatment for Parkinson's disease (PD), but long‐term use commonly leads to motor complications such as levodopa‐induced dyskinesia (LID) and motor fluctuations, significantly contributing to disability. Exercise is well‐established for improving motor and non‐motor symptoms in PD;
Priscila Nóbrega‐Sousa, Lucas H.C.C. Santos, Jane Alty, Peter Humburg, Kim Delbaere, Paulo H.S. Pelicioni   +5 more
wiley   +1 more source

Synergetic effect of a DSP4-induced locus coeruleus lesion and systemic LPS exacerbates substantia nigra dopaminergic neuron loss. [PDF]

Sci Rep
Şimşek F, Papová D, Henriksson E, Olmedo-Díaz S, Blyberg M, El-Habta R, Virel A, Af Bjerkén S.   +7 more
europepmc   +1 more source

Mitochondrial DNA Damage in Substantia Nigra Pars Compacta Astrocytes Exacerbates Dopaminergic Neuron Loss in a 6-Hydroxydopamine Mouse Model of Parkinsonism. [PDF]

Cell Mol Neurobiol
Ayala DA, Hall GM, Das D, Tijerina E, Villagran LL, Khan Z, Paliwal D, Anand A, Rimer M, Srinivasan R.   +9 more
europepmc   +1 more source

Dopaminergic Neuron-Derived AIMP1 Promotes Neurodegeneration via CD23-Dependent Microglial Activation. [PDF]

CNS Neurosci Ther
Wang Q, Yu H, Yuan X, Li R, Li X, Yin S, Ma X, Wang X.   +7 more
europepmc   +1 more source

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis, Omer Anis, Abhishek Lenka, Junaid H. Siddiqui   +3 more
wiley   +1 more source

A simplified model of dopaminergic neuron

BMC Neuroscience, 2008
Oprisan Sorinel
doaj   +1 more source

Therapeutic Effects of Noninvasive Electrical Stimulation in Combination Transplantation of Human Adipose-Derived Stem Cells-Derived Dopaminergic Neuron on the Monkey Model of Parkinson's Disease. [PDF]

MedComm (2020)
Huang C, Gao S, Zheng X, Song X, Wu J, Liao K, Li J, Lin Y, Li C, Lu Y, Feng J, Wei H, Wang L, Xu H, Wang W, Chen Y, Wu J, Gao J, Song J, Shi C, Zhang J, Yan S.   +21 more
europepmc   +1 more source