The Hyperpolarization-Activated Current Determines Synaptic Excitability, Calcium Activity and Specific Viability of Substantia Nigra Dopaminergic Neurons [PDF]
Carmen Carbone +4 more
openalex +1 more source
The Impact of Mitochondrial Dysfunction on Dopaminergic Neurons in the Olfactory Bulb and Odor Detection [PDF]
Thomas Paß +6 more
openalex +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
One of the hallmarks of Parkinson's Disease (PD) is aggregation of incorrectly folded α-synuclein (SNCA) protein resulting in selective death of dopaminergic neurons.
Sonia Narwal, Amit Singh, Meghana Tare
doaj +1 more source
Silk fibroin‐based biomaterials for spinal cord injury repair: Recent advances and future prospects
A comprehensive review on the design principles and current strategies of silk fibroin‐based biomaterials in spinal cord injury repair, focusing on environmentally friendly processing techniques, and the strategies for designing composite scaffolds as well as discussing the advantages and current challenges of silk fibroin‐based biomaterials in spinal ...
Xiaoliang Cui +7 more
wiley +1 more source
Quantification of dopaminergic neuron differentiation and neurotoxicity via a genetic reporter [PDF]
Jun Cui +5 more
openalex +1 more source
Neuronal differentiation and tissue engineering strategies for central neurous system injury repair
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia +9 more
wiley +1 more source
Platelet‐derived growth factor (PDGF)‐BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase [PDF]
Huan Chen +8 more
openalex +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
The Parkinson’s disease associated Leucine-rich repeat kinase 2 affects expression of Transferrin receptor 1 and phosphorylation of key signaling proteins in human iPSC-derived dopaminergic neurons [PDF]
Natalja Funk +5 more
openalex +1 more source

