Results 251 to 260 of about 199,386 (303)

Muscarinic Receptor Activation Preferentially Inhibits Rebound in Vulnerable Dopaminergic Neurons. [PDF]

J Neurosci
Beaver ML, Evans RC.
europepmc   +1 more source

Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies

Movement Disorders, EarlyView.
Abstract Alpha‐synuclein (aSyn), historically studied for its synaptic functions and central role in Lewy body pathology, is emerging as a protein with significant nuclear activities relevant to Parkinson's disease (PD) and related synucleinopathies. Recent advances reveal that aSyn dynamically localizes to neuronal nuclei in both health and disease ...
Tiago Fleming Outeiro, David J. Koss
wiley   +1 more source

Manganese Porphyrin Reduces Oxidative Stress in Vulnerable Parkin-Null <i>Drosophila</i> Dopaminergic Neurons. [PDF]

Antioxidants (Basel)
Juba AN, Keoseyan PP, Hamel RP, Margaryan T, Barber ML, Foley AN, Jones TB, Batinic-Haberle I, Tovmasyan A, Buhlman LM.   +9 more
europepmc   +1 more source

Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review

Movement Disorders, EarlyView.
Abstract Background Most individuals with Parkinson's disease (PD) develop dysphagia during the course of their disease. It is crucial to comprehensively understand swallowing characteristics specific to PD for effective treatment. Objectives To systematically analyze and synthesize swallowing characteristics in people with PD compared with healthy ...
Kerstin Erfmann, Julia Hirschwald, Jule Hofacker, Katharina Winiker, Juliane Klann, Rainer Dziewas, Tobias Warnecke   +6 more
wiley   +1 more source

The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons. [PDF]

Front Pharmacol
Zhao S, Liu S, Gong Y, Ma Z.
europepmc   +1 more source

Modulation of Non‐Rhythmic Temporal Prediction by Subthalamic Nucleus Deep Brain Stimulation (STN‐DBS) in Parkinson's Disease

Movement Disorders, EarlyView.
Background Accurate temporal prediction, essential for adaptive motor behavior, relies on corticobasal ganglia circuits. In Parkinson's disease (PD), both motor and non‐motor functions are impaired. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) effectively alleviates motor symptoms, but its effects on non‐motor domains, like temporal ...
Rebecca Burke, Marleen J. Schoenfeld, Christian K.E. Moll, Alessandro Gulberti, Monika Pötter‐Nerger, Andreas K. Engel   +5 more
wiley   +1 more source

Vesicular monoamine transporter 2 (VMAT2) overexpression in inferior colliculus (IC)-innervated substantia nigra compacta (SNc) dopaminergic neurons ameliorates noise exposure-induced 6-hydroxydopamine (6-OHDA) vulnerability.

Chi Cui (10201007), Yibo Yao (16274454), Yulong Shi (459712), Jie Lei (579923), Kun Ren (6173954), Kexing Wan (6258182), Tongxia Li (13354935), Gangan Luo (16999848), Qian Xu (119888), Ming Li (91180), Xiang Peng (3092073), Xueke Yang (14648669), Jian Yang (12136), Junsong Du (22559804), Sitong Chen (170590), Bo Tian (625365), Pei Zhang (232846)   +16 more
openalex   +1 more source

Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids

Movement Disorders, EarlyView.
Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson’s disease models

Valencia-Alarćon EP, Duret LC, Kobayashi E, Cattaneo O, Schneider BL, Nagoshi E.   +5 more
europepmc   +1 more source