Results 241 to 250 of about 194,049 (307)

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

Differential Effects of Murine Stroke Models on Dopaminergic Neurons, Glial Responses, and Neurobehavioral Outcomes. [PDF]

Transl Stroke Res
Tabassum S, Hu H, Wu S, Huang S, Yang BSK, Lee CH, Gusdon AW, Ren XS.   +7 more
europepmc   +1 more source

Metabolic and Volumetric Alterations in the Basal Ganglia and the Cerebellum in Dopa‐Responsive Dystonia in Symptomatic and Asymptomatic GCH1 Mutation Carriers

Movement Disorders, EarlyView.
ABSTRACT Background Dopa‐responsive dystonia is caused by pathogenic variants in the GCH1 gene. Although its clinical features and reduced penetrance are known, in vivo metabolic and structural alterations in symptomatic (sMC) and asymptomatic mutation carriers (aMC) remain poorly understood.
Jannik Prasuhn, Leon van Well, Marta M. Pokotylo, Feline Hamami, Joke‐Lina Aßmann, Katja Lohmann, Maximilian G. Ködderitzsch‐Mertins, Julia Henkel, Jan Uter, Alexander Münchau, Christine Klein, Anne Weissbach, Norbert Brüggemann   +12 more
wiley   +1 more source

Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories. [PDF]

Nat Commun
Sansalone L, Twedell EL, Evans RC, Boronat-Garcia A, Zhang R, Khaliq ZM.   +5 more
europepmc   +1 more source

Bacteroides coprocola protects dopaminergic neurons in rotenone-induced Parkinson's disease mouse model by modulating gut microbiota dysbiosis and inhibiting the NLRP3 signaling pathway. [PDF]

Transl Neurodegener
Liu Z, Nie J, Li Y, Huang M, Chen Z, Yu S, Zheng J, Tan Y, Chen S.   +8 more
europepmc   +1 more source

Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons. [PDF]

Sci Rep
Gorgogietas V, Weiss A, Cousin L, Hoffmann D, Schmitt K, Ogier A, Barbuti PA, Santos BFR, Boussaad I, Wittich A, Zaliani A, Pless O, Krüger R, Sommer P, Wilbertz JH.   +14 more
europepmc   +1 more source

Protocol for 3D direct reprogramming of human glia into dopaminergic neurons with gene expression and immunocytochemistry validation. [PDF]

STAR Protoc
Giacomoni J, Laurin K, Parmar M, Habekost M.   +3 more
europepmc   +1 more source