Results 251 to 260 of about 122,423 (305)
NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson’s disease models
Valencia-Alarćon EP +5 more
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Noradrenergic Modulation on Dopaminergic Neurons
Neurotoxicity Research, 2018 It is now well accepted that there is a close relationship between noradrenergic and dopaminergic neurons in the brain, especially referring to the modulation of the locus coeruleus-norepinephrine (LC-NE) system on dopamine transmission. The disturbance of this modulation may contribute to neurodegeneration of dopaminergic neurons in Parkinson's ...
Meng-Yang Zhu, Zhu, Meng Yang
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The International Journal of Biochemistry & Cell Biology, 2005
Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons are found in a 'harsh' region of the brain, the substantia nigra pars compacta, which is DA-rich and ...
Shankar J, Chinta, Julie K, Andersen
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Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons are found in a 'harsh' region of the brain, the substantia nigra pars compacta, which is DA-rich and ...
Shankar J, Chinta, Julie K, Andersen
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Dopaminergic neurons intrinsic to the striatum
Journal of Neurochemistry, 2007AbstractThe striatum – the largest integrative component of the basal ganglia – harbors a population of neurons that express the enzyme tyrosine hydroxylase (TH), a faithful marker of dopaminergic neurons. The dopaminergic nature of these neurons is further supported by the fact that they express the dopamine (DA) transporter (DAT) and the nuclear ...
Philippe, Huot, André, Parent
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Toxicity of semaphorin3A for dopaminergic neurons
Neuroscience Letters, 2005Semaphorin3A (Sema3A) is known to cause neuronal apoptosis and serves as a chemorepellent factor for axonal growth. In our previous report, we found that Sema3A was up-regulated in the 6-OHDA-injected striatum of rats, suggesting that Sema3A was likely involved in dopaminergic (DA) depletion.
Takao, Yasuhara +11 more
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Dopaminergic neurons in the human retina
Journal of Comparative Neurology, 1982AbstractThe utilization of dopamine in the adult human retina was examined by using high‐affinity uptake, localization, synthesis, and release as neurotransmitter‐specific physiological probes. Autoradiographic and histochemical studies have shown that dopamine‐accumulating and dopamine‐containing cells of the human retina belong to a population of ...
J M, Frederick +4 more
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Dopaminergic Dependency of Cholinergic Pallidal Neurons
Neuroscience, 2023We employed the whole-cell patch-clamp method and ChAT-Cre mice to study the electrophysiological attributes of cholinergic neurons in the external globus pallidus. Most neurons were inactive, although approximately 20% displayed spontaneous firing, including burst firing.
Janintzitzic López-Niño +7 more
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Dopaminergic neurons for Parkinson's therapy
Nature Biotechnology, 2012A differentiation protocol guided by developmental principles produces more-authentic dopaminergic neurons for transplantation in patients.
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The organization of dopaminergic and non-dopaminergic mesencephalo-cortical neurons in the rat
Brain Research, 1982The dopamine containing mesencephalo-cortical pathway was studied in the rat by means of a combined retrograde fluorescent tracing and catecholamine histofluorescence technique. After large injections of the fluorescent retrograde tracer, Evans blue, into the frontal cortex, many neural somata of the ventral midbrain tegmentum were retrogradely labeled;
Albanese, Alberto, Bentivoglio, M.
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