Results 221 to 230 of about 598,888 (295)

HUWE1 regulates mitophagy to protect dopaminergic neurons from 6-OHDA- and MPP⁺-induced neurotoxicity. [PDF]

Cell Biol Toxicol
Lee C, Kim DY, Kim SM, Han IO.
europepmc   +1 more source

Association Between Long‐Term Exposure to Air Pollution and Parkinson's Disease: Administrative Cohort of Older Adults in South Korea

Movement Disorders, EarlyView.
Abstract Background Evidence regarding the association between long‐term exposure to ambient air pollution and Parkinson's disease (PD) remains inconsistent, particularly among older adults in Asian populations. Objective We aimed to examine the association between long‐term exposure to ambient air pollutants and incident PD in a nationwide ...
Jongmin Oh, Jisun Myung, Dong‐Wook Lee, Changwoo Han, Yun‐Chul Hong, Soontae Kim, Yoon‐Hee Kang, Hyun‐Joo Bae, Youn‐Hee Lim   +8 more
wiley   +1 more source

Correction to "Evaluation of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Siblings with Gaucher Disease Discordant for Parkinsonism". [PDF]

Mov Disord
europepmc   +1 more source

Microglial low-affinity FcγR mediates the phagocytic elimination of dopaminergic neurons in Parkinson's disease degeneration. [PDF]

NPJ Parkinsons Dis
Casanova PV, Freitag-Berenguel I, Saavedra-López E, Usandizaga-Estarloa M, Ríos-Cuadrado C, Martínez-Remedios P, Giménez-Montes C, Clinton E, Roig-Martínez M, Cribaro GP, Barcia C.   +10 more
europepmc   +1 more source

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

Movement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju, Anette Schrag, Camille Carroll, Xi Xiong, James Carpenter, Oliver Bandmann, Thomas Foltynie, Li Wei   +7 more
wiley   +1 more source

<i>foxQ2</i> marks fast-acting interneurons including dopaminergic neurons of <i>mushroom bodies</i> and <i>central complex</i> in the beetle <i>Tribolium castaneum</i>. [PDF]

Elife
Pang Y, Klußmann-Fricke B, Cedden D, Zhang J, Schinko JB, Averof M, Riemensperger TD, Bucher G.   +7 more
europepmc   +1 more source

Lysosomal Expression Profile in Plasma Associates with Disease Severity in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a clinically and biologically heterogeneous neurodegenerative disorder, driven by multiple mechanisms among which are lysosomal and mitochondrial dysfunction. Here, we explored blood‐based lysosomal and mitochondrial profiles in relation to PD diagnosis and severity.
Janna van Wetering, Manon M. van Ingen, Evelien Timmermans, Sjors G.J.G. in't Veld, Henk W. Berendse, Charlotte E. Teunissen, Wilma D.J. van de Berg   +6 more
wiley   +1 more source

Oleuropein Attenuates 6-Hydroxydopamine-Induced Cytotoxicity Through Redox Regulation in Differentiated Dopaminergic Neurons: Potential Involvement of RET-Associated Signalling. [PDF]

Int J Mol Sci
Ahmed BY, Lange S, Warda M, Shadidizaji A, Uysal-Onganer P.   +4 more
europepmc   +1 more source

Striatal Dopaminergic Reserve Shapes the Longitudinal Impact of Peripheral Immune Activation on Motor Progression in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Peripheral immune dysregulation has been implicated in Parkinson's disease (PD) progression, but whether motor deterioration reflects accelerated nigrostriatal degeneration or residual dopaminergic reserve remains unclear. Objectives To examine whether baseline and time‐varying neutrophil‐to‐lymphocyte ratio (NLR) relate to motor ...
Osman Kahveci, Ulaş Ay, Tamer Demiralp
wiley   +1 more source

Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons. [PDF]

Neuropsychopharmacology
Huang Y, Michalski C, Zhou Y, Xu C, Niu W, Lucido MJ, Wang J, Feng Y, Miller AH, Wen Z.   +9 more
europepmc   +1 more source