Results 201 to 210 of about 598,888 (295)

Neuropsychiatric‐Led Presentation of Late‐Onset Parkin‐Related Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Sarah Fullam, Shane Lyons, Martha Finnegan, Richard Walsh, Sean O'Dowd   +4 more
wiley   +1 more source

Digital Handwriting Reveals Motor Impairment, Dopaminergic Response, and Progression in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Digital handwriting distinguishes PD patients from healthy controls but is rarely assessed quantitatively. Objectives To evaluate digital handwriting as an objective tool to assess motor impairment, dopaminergic response, and progression in PD.
Lola Díaz‐Feliz, Marcos Faundez‐Zanuy, Andrea Gennari, Alexia Sánchez‐Reyes, Pilar Sanz‐Cartagena, José Arbelo‐González, Miguel Ángel García‐Cabezas, Pedro García‐Ruiz   +7 more
wiley   +1 more source

Evaluation of a commercial AI-assisted cell counting software for dopaminergic neurons across species. [PDF]

PLoS One
Kunugitani K, Sawamura M, Taguchi T, Hirato T, Uemura N, Ayaki T, Nakanishi E, Yamakado H, Ishimoto T, Onoe H, Isa T, Matsumoto R, Takahashi R.   +12 more
europepmc   +1 more source

Should Paratonia Be Considered a Movement Disorder? Implications for Clinical Management

Movement Disorders Clinical Practice, EarlyView.
Abstract Paratonia is an involuntary and variable resistance to passive movement that emerges with cognitive decline in dementias of different etiologies, with prevalence approaching 90% to 100% in end‐stage disease. It is common in Parkinson disease and the atypical parkinsonisms.
Galit Kleiner, Christos Ganos, Anthony E. Lang   +2 more
wiley   +1 more source

Microengineering of the capillary interface of midbrain dopaminergic neurons to study Parkinson's disease vascular alterations. [PDF]

Commun Eng
Alim A, Baek Y, Lee M, Paek J.
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons via aberrant p38 MAPK activation. [PDF]

NPJ Parkinsons Dis
Zhao J, Chen Y, Zhi L, Xu Q, Subiry J, Chen Z, Cui S, Zhang H, Li C.   +8 more
europepmc   +1 more source

Acute Post‐Partum Psychosis and Dystonia Reveals Late‐Onset MPAN

Movement Disorders Clinical Practice, EarlyView.
Mathilde Lachaume, Audrey Schalk, Nadège Calmels, Christine Tranchant, Ozanne de Andrade, Fabrice Berna, Mathieu Anheim, Thomas Wirth   +7 more
wiley   +1 more source

Decoding the Gut‐Brain Axis: Multi‐Omics Reveals a Causal Chain Linking Human Genome, Gut Microbiota, Blood Metabolites, and Alertness in the Brain

Med Research, EarlyView.
This multi‐omics study identified genetic loci, gut microbiota, blood metabolites, and gray matter volumes of orbitofrontal cortex and cerebellum that were potentially relevant to alerting in healthy Chinese adults. Subsequent two‐step one‐sample Mendelian randomization further revealed a serial mediation pathway: Bacteroides intestinalis influences ...
Hongru Li, Chuansheng Chen, Ofir Turel, Yu Pu, Hong Chen, Tingyong Feng, Jiang Qiu, Xu Lei, Qinghua He   +8 more
wiley   +1 more source