Results 91 to 100 of about 6,860 (236)

Various Bacillus and Paenibacillus Spp. Isolated From Soil Produce Compounds With Potent Antimicrobial Activity Against Clinically Relevant Pathogens

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study identified soil‐derived Bacillus and Paenibacillus strains with broad‐spectrum antimicrobial activity, including 97% inhibition of CREs by Paenibacillus profundus. Genome mining revealed biosynthetic gene clusters (NRPSs, PKSs, RiPPs) linked to antimicrobial production, highlighting their potential in combating antibiotic resistance. Created
Michael Moran, Hogan Turner, Joseph Yanchar, Joshua Preece, Gene Ahlborn, Richard Robison   +5 more
wiley   +1 more source

Therapeutic Drug Monitoring of Continuous Infusion Doripenem in a Pediatric Patient on Continuous Renal Replacement Therapy

, 2017
An 11-year-old African American male with severe combined immunodeficiency variant, non-cystic fibrosis bronchiectasis, pancreatic insufficiency, chronic mycobacterium avium-intracellulare infection, chronic sinusitis, and malnutrition presented with a 1-
Wayne S. Moore, Jeffrey J. Cies, Susan B. Conley, Paul Shea, Arun Chopra, Adela Enache   +5 more
core   +1 more source

Pharmacokinetics of doripenem in plasma and epithelial lining fluid (ELF): comparison of two dosage regimens

European Journal of Clinical Pharmacology, 2017
In 2014, FDA released a warning for prescription of doripenem for ventilator-associated bacterial pneumonia due to unsatisfactory clinical cure rates. The present study explores if the observed lack of efficacy might be explained by insufficient target ...
Z. Oesterreicher, Iris K. Minichmayr, R. Sauermann, D. Marhofer, E. Lackner, W. Jäger, A. Maier‐Salamon, R. Schwameis, C. Kloft, M. Zeitlinger   +9 more
semanticscholar   +1 more source

A Novel Carbapenem; Doripenem Monohydrate

, 2013
Karbapenem grubunun 2007 yılında FDA (Food and Drug Administration) onayı alan en son üyesi doripenem monohidrat, 1 beta metil grubu içeren sentetik bir analogtur. Doripenem, di er karbapenemler gibi konsantrasyona de il, zamana ba ımlı bakterisidal etki
Dikici, Nebahat, Sümer, Şua
core  

Comparative activity of carbapenem testing (the COMPACT study) in Turkey

BMC Infectious Diseases, 2012
Background Recent evidence indicates that Gram-negative bacterial pathogens, the most common of which are Pseudomonas spp., Enterobacteriaceae, and Acinetobacter baumannii, are frequent causes of hospital-acquired infections.
Leblebicioglu Hakan, Cakir Nedim, Celen Mustafa, Kurt Halil, Baris Hakan, Laeuffer Joerg   +5 more
doaj   +1 more source

Doripenem (Doribax): The Newest Addition to the Carbapenems [PDF]

Baylor University Medical Center Proceedings, 2008
Carbapenems are a class of antimicrobials structurally related to penicillin. Doripenem, the newest agent in this class, was recently approved by the Food and Drug Administration for the treatment of complicated intra-abdominal infections and complicated urinary tract infections.
openaire   +2 more sources

Preparation and characterization of formic acid modulated HKUST-1 for doripenem drug delivery [PDF]

, 2022
Doripenem is an antibiotic with high effectiveness in treating infections. However, the dose of doripenem is only partially used, so the rest will be wasted through the secretory system.
Denesa, Erwhyanta Monorizho, Yohanes, Steven   +1 more
core  

In Vitro Activities of Ceftobiprole and Doripenem Tested against Frequently Encountered Aerobic and Facultative Gram-Positive and Gram-Negative Bacterial Pathogens Isolated from Patients in Canadian Hospitals in 2007

Canadian Journal of Infectious Diseases and Medical Microbiology, 2009
BACKGROUND: In 2008, ceftobiprole was approved by Health Canada for the treatment of patients with complicated skin and skin structure infections including diabetic foot infections; approval of ceftobiprole by the United States Food and Drug ...
James A Karlowsky, Mel DeCorby, Daryl J Hoban, George G Zhanel   +3 more
doaj   +1 more source

Isolation and identification of Klebsiella pneumonia from wound infections and study of the synergistic effect of carpenems and cefepime

مجلة علوم ذي قار
Surgical site infection (SSI) is a major source of morbidity and mortality in developing countries despite recent advances in sterile techniques. We studied antibiotics through their effect on bacterial pathogens isolated from wound infections singly ...
Ali Qasim, Hind Abdullah Salih
doaj   +1 more source

Experimental and modelling study of adsorption isotherms of amoxicillin, ampicillin and doripenem on bentonite-chitosan composite

South African Journal of Chemical Engineering, 2022
Jason Yi Juang Yeo, D. S. Khaerudini, F. Soetaredjo, G. Waworuntu, S. Ismadji, A. Putranto, J. Sunarso   +6 more
semanticscholar   +1 more source