Results 81 to 90 of about 6,860 (236)

Insights of β‐Lactams Resistance in Klebsiella pneumoniae Clinical Isolates: A Focus on Molecular Identification of Drug Resistance

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is associated with high antimicrobial resistance and is commonly isolated from colonization and healthcare‐associated infections (HAIs). This study is aimed at developing and validating molecular assays to detect resistance genes belonging to the bla family in resistant K. pneumoniae isolates.
Lavouisier F. B. Nogueira, Marília S. Maia, Marco A. F. Clementino, Ila F. N. Lima, Jorge L. N. Rodrigues, Luciana V. C. Fragoso, Glairta S. Costa, Jose Q. S. Filho, Alexandre Havt, Deiziane V. S. Costa, Lyvia M. V. C. Magalhães, Dilza Silva, José K. Sousa, Aldo A. M. Lima, Divakar Sharma   +14 more
wiley   +1 more source

Investigating the Effect of Xylitol on ompK36 Overexpression, Increased Meropenem Susceptibility, and Antibiofilm Activity in a Carbapenem‐Resistant Clinical Strain of Klebsiella pneumoniae

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Carbapenem‐resistant Klebsiella pneumoniae poses a significant public health threat due to limited therapeutic options. This study investigated the potential of xylitol, a sugar alcohol, to enhance meropenem activity and combat biofilms in a clinical carbapenem‐resistant K. pneumoniae strain (Kp5) and a standard susceptible strain (K. pneumoniae subsp.
Omid Ahlelyorof, John Flanagan, Fereshteh Jabalameli, Reza Beigverdi, Maryam Siroosi, Divakar Sharma   +5 more
wiley   +1 more source

Investigation of Tigecycline Resistance Mechanisms in Escherichia coli and Klebsiella pneumoniae Isolates From Hospitalized Patients in Selected Tehran Hospitals During 2022–2023

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Escherichia coli and Klebsiella pneumoniae are recognized as significant opportunistic pathogens responsible for a substantial proportion of hospital‐acquired infections. The growing prevalence of multidrug resistance in isolates of these pathogens represents a critical global health concern.
Mohsen Javidi, Zohreh Ghalavand, Javad Yasbolaghi Sharahi, Amirhossein Fayyazi, Maryam Tarhani, Taha Saleh, Farahnoosh Doustdar, Ali Hashemi, Shweta Negi   +8 more
wiley   +1 more source

Mapping the Threat: A Scoping Review of Acinetobacter baumannii–Associated Hospital Infections and Resistance Mechanisms

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Acinetobacter baumannii is a major cause of hospital‐associated infections (HAIs) globally, particularly in intensive care units (ICUs). Its remarkable environmental resilience and ability to acquire extensive antimicrobial resistance (AMR) have made it a critical threat to patient safety and a top priority pathogen according to the World ...
Yussif Owusu Aboagye, Muhi-deen Wonwana Mohammed, Kwame Kumi Asare, Mohamed Salah Abbassi   +3 more
wiley   +1 more source

Doripenem: A new carbapenem antibiotic a review of comparative antimicrobial and bactericidal activities [PDF]

, 2007
Doripenem is a new parental 1-β-methyl carbapenem which, unlike imipenem, does not require the addition of cilastatin on administration because of the protection afforded to doripenem by the 1-β-methyl component.
Walsh, Fiona
core  

ANTIMICROBIAL THERAPY OF PATIENTS WITH FAN-ASSOCIATED PNEUMONIA: FOCUS ON DOPIRENEM

Медицинский совет, 2016
The fan-associated pneumonia currently is a leading reason of mortality of patients in resuscitation and intensive care unit. Development of the disease is accompanied by serious clinical and economic consequences.
O. V. FESENKO
doaj   +1 more source

Antibiotic Use in Livestock: A Driver of Resistance in Africa and the Path to Safer Alternatives

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The incorporation of antibiotics into animal feeds is one of the drivers of antibiotic resistance, a global One Health challenge. To reduce the burden of antibiotic resistance, the use of alternative growth promoters and drugs must be promoted, as well as sensitization and implementation of regulations.
Mercy A. Alabi, Hafizah Y. Chenia, Johnson Lin   +2 more
wiley   +1 more source

MODERN ANTIBACTERIAL THERAPY IN HOSPITAL-ACQUIRED PNEUMONIA

Медицинский совет, 2017
Hospital-acquired pneumonia terminologically unites all types of pneumonia that arise in hospitalized patients: pneumonia in patients beyond artificial lungs ventilation (hospital pneumonia, medical aid-associated pneumonia) and hospital acquired ...
V. B. Beloborodov, V. A. Sinikin
doaj   +1 more source

Antibacterial Potential of Actinomycete Extracts and Characterization of β‐Lactamase‐Producing Multidrug‐Resistant Uropathogenic Escherichia coli

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Antibacterial Potential of Actinomycete Extracts Against Multidrug‐Resistant Escherichia coli in Babil Province, Iraq. ABSTRACT The increasing prevalence of multidrug‐resistant (MDR) uropathogenic Escherichia coli (UPEC) strains, particularly those producing β‐lactamase enzymes, complicates urinary tract infection (UTI) treatment and poses a ...
Hoda Khaledi, Nour Oude Obeid
wiley   +1 more source

In Vitro Interactions of Antibiotic Combinations of Colistin, Tigecycline, and Doripenem Against Extensively Drug-Resistant and Multidrug-Resistant Acinetobacter baumannii

, 2017
BACKGROUND: Acinetobacter baumannii infections are difficult to treat owing to the emergence of various antibiotic resistant isolates. Because treatment options are limited for multidrug-resistant (MDR) A.
정석훈
core   +1 more source