Results 61 to 70 of about 5,549 (198)

Role of efflux pumps inhibitor in decreasing antibiotic resistance of Klebsiella pneumoniae in a tertiary hospital in North India

open access: yesJournal of Infection in Developing Countries, 2015
Introduction: The contribution of efflux systems to drug resistance in Enterobacteriaceae is becoming increasingly appreciated. This study phenotypically analyzed the role of efflux mechanisms in resistance to ertapenem, doripenem, and tigecycline among ...
Joel Filgona   +2 more
doaj   +1 more source

Antimicrobial resistance surveillance of doripenem in China [PDF]

open access: yesThe Journal of Antibiotics, 2015
To investigate the antibacterial resistance to doripenem in China and to understand the distribution trends of resistant bacteria. All the clinical isolates were collected from hospitals and the susceptibility tests were performed using the agar dilution method recommended by the Clinical Laboratory Standards Institute (CLSI) central laboratory.
Yun, Li   +5 more
openaire   +2 more sources

Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin

open access: yesMicrobial Biotechnology, Volume 19, Issue 1, January 2026.
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley   +1 more source

Antimicrobial activity of doripenem against Gram-negative pathogens: results from INVITA-A-DORI Brazilian Study

open access: yesBrazilian Journal of Infectious Diseases, 2011
In vitro activity of doripenem and comparator antimicrobial agents was evaluated against Gram-negative bacilli recently isolated from Brazilian private hospitals that were enrolled in the INVITA-A-DORI Brazilian Study. A total of 805 unique Gram-negative
Ana Cristina Gales, PhD in Medicine   +4 more
doaj   +1 more source

Structural Characterization and Functional Annotation of Hypothetical Proteins in the Multidrug‐Resistant Strains of Pseudomonas aeruginosa

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Pseudomonas aeruginosa is a leading cause of severe nosocomial infections worldwide. This opportunistic pathogen is associated with increased morbidity and mortality rates due to its high levels of antibiotic resistance. The identification of novel therapeutic targets is therefore a pressing global health priority.
Fatemeh Nasiri Khoonsari   +2 more
wiley   +1 more source

In Vitro Activity of Doripenem compared to Meropenem against Pseudomonas aeruginosa isolates at Tertiary Care Teaching Hospital in Bogotá (Colombia) [PDF]

open access: yes, 2021
Objetivo: El objetivo de este estudio fue evaluar la actividad in vitro de doripenem comparado con meropenem frente a aislamientos locales de Pseudomonas aeruginosa (P. aeruginosa). Materiales y métodos: En el Hospital San José de Bogotá (Colombia), un
Fajardo, Claudia, Jiménez, Adriana
core  

An Investigation of Colistin Heteroresistance in Klebsiella pneumoniae Isolates in Iran

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Background According to the World Health Organization 2024 bacterial priority pathogens list, carbapenem‐resistant Enterobacterales (CRE) were listed among the critical priority pathogens. Heteroresistance (i.e., a bacterial isolate that appears susceptible but harbors resistant subpopulations) represents a challenge in traditional laboratory testing ...
Zohreh Riahi Rad   +8 more
wiley   +1 more source

ANTIMICROBIAL THERAPY OF PATIENTS WITH FAN-ASSOCIATED PNEUMONIA: FOCUS ON DOPIRENEM

open access: yesМедицинский совет, 2016
The fan-associated pneumonia currently is a leading reason of mortality of patients in resuscitation and intensive care unit. Development of the disease is accompanied by serious clinical and economic consequences.
O. V. FESENKO
doaj   +1 more source

Acinetobacter baumannii in the Age of Antimicrobial Resistance: Clinical Impact, Therapeutic Approaches, and Vaccine Development

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Acinetobacter baumannii is a globally prevalent Gram‐negative pathogen responsible for a substantial proportion of healthcare‐associated infections, particularly in intensive care units. Its ability to persist in hospital environments, form biofilms on medical devices, and evade host immune responses has contributed to the rapid emergence of multidrug ...
Krupa Bhaliya   +7 more
wiley   +1 more source

MODERN ANTIBACTERIAL THERAPY IN HOSPITAL-ACQUIRED PNEUMONIA

open access: yesМедицинский совет, 2017
Hospital-acquired pneumonia terminologically unites all types of pneumonia that arise in hospitalized patients: pneumonia in patients beyond artificial lungs ventilation (hospital pneumonia, medical aid-associated pneumonia) and hospital acquired ...
V. B. Beloborodov, V. A. Sinikin
doaj   +1 more source

Home - About - Disclaimer - Privacy