Results 41 to 50 of about 6,860 (236)

UHPLC–MS/MS method for simultaneous quantification of doripenem, meropenem, ciprofloxacin, levofloxacin, pazufloxacin, linezolid, and tedizolid in filtrate during continuous renal replacement therapy

Journal of clinical laboratory analysis (Print), 2022
Since severe infections frequently cause acute kidney injury (AKI), continuous renal replacement therapy (CRRT) is often initiated for regulation of inflammatory mediators and renal support.
Makoto Kai, Ryota Tanaka, Yosuke Suzuki, K. Goto, Y. Ohchi, Norihisa Yasuda, R. Tatsuta, T. Kitano, H. Itoh   +8 more
semanticscholar   +1 more source

Auranofin promotes antibacterial effect of doripenem against carbapenem‐resistant Acinetobacter baumannii

Journal of Applied Microbiology, 2022
This study was performed to identify the potential for repurposing auranofin as an antibiotic adjuvant against carbapenemase‐producing Acinetobacter baumannii.
H.R. Kim, Yong-Bin Eom
semanticscholar   +1 more source

Comparison of in Vitro Activity of Doripenem versus Old Carbapenems against Pseudomonas Aeruginosa Clinical Isolates from both CF and Burn Patients [PDF]

Advanced Pharmaceutical Bulletin, 2013
Purpose: The antimicrobial activity of doripenem in comparison of imipenem, meropenem and ertapenem among Pseudomonas aeruginosa isolated from burn and Cystic Fibrosis (CF) patients were determined.
Reza Bigverdi, Mona Ghazi, Mostafa Davodi, Tahereh Pirzadeh, Morteza Ghojazadeh, Mohammad Hossein Soroush, Mohammad Reza Nahaei, Mohammad Ahangarzadeh Rezaee, Zoya Hojabri, Omid Pajand, Mohammad Aghazadeh   +10 more
doaj   +1 more source

Anti-Mutant Efficacy of Combination Therapy with Doripenem and Levofloxacin: In Vitro Model Studies with Pseudomonas Aeruginosa

Антибиотики и Химиотерапия, 2021
Relevance. The tendency to a decrease in sensitivity of bacterial agents to old antibiotics, as well as the slowdown in creation of new medications, dictate the need to develop effective approaches to combat bacterial resistance.Aim.
M. V. Golikova, E. N. Strukova, K. N. Alieva, A. V. Filimonova, Yu. A. Portnoy, A. A. Firsov   +5 more
doaj   +1 more source

A bio-analytically validated HPLC-UV method for simultaneous determination of doripenem and ertapenem in pharmaceutical dosage forms and human plasma: a dual carbapenem regimen for treatment of drug-resistant strain of Klebsiella pneumoniae

RSC Advances, 2021
The emergence of strains resistant to certain antibiotics is turning into an important issue worldwide that threatens global health with the increasing incidence of carbapenemase-producing Klebsiella pneumoniae (KPC). Thus, successful doripenem–ertapenem
Marwa F. B. Ali, Mostafa A. Marzouq, S. Hussein, Baher I. Salman   +3 more
semanticscholar   +1 more source

In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model

Frontiers in Pharmacology, 2021
Background: Elimination of a drug during renal replacement therapy is not only dependent on flow rates, molecular size and protein binding, but is often influenced by difficult to predict drug membrane interactions.
M. Vossen, S. Pferschy, C. Milacek, M. Haidinger, M. Karolyi, Zoltán Vass, H. Burgmann, A. Maier‐Salamon, S. Wicha, W. Jäger, M. Zeitlinger, T. Stimpfl, T. Wittek, F. Thalhammer   +13 more
semanticscholar   +1 more source

PREPARATION OF ANTIBACTERIAL BENTONITE β LACTAM ANTIBIOTIC COMPOSITE

EQA, 2018
The adsorption of Doripenem (beta-lactam antibiotic belonging to the subgroup carbapenem) from aqueous solution using bentonite as the adsorbent was studied at various pH of the solution. The doripenem loaded in bentonite which called doripenem-bentonite
Gladdy Waworuntu, Gisela Anke Hanelin, Lukius Denny Wiyanto, Livy Laysandra, Felycia Edi Soetaredjo   +4 more
doaj   +1 more source

Carbapenem Combinations for Infections Caused by Carbapenemase-Producing Pseudomonas aeruginosa: Experimental In Vitro and In Vivo Analysis

Antibiotics, 2022
In the context of difficult-to-treat carbapenem-resistant Pseudomonas aeruginosa infections, we evaluated imipenem, meropenem, and doripenem combinations against eleven carbapenemase-producing P. aeruginosa isolates.
Soraya Herrera-Espejo, Ester Del Barrio-Tofiño, Tania Cebrero-Cangueiro, Carla López-Causapé, Rocío Álvarez-Marín, José Miguel Cisneros, Jerónimo Pachón, Antonio Oliver, María Eugenia Pachón-Ibáñez   +8 more
doaj   +1 more source

Doripenem: A new carbapenem in clinical practice [Doripenem: Klinik uygulamada yeni bir karbapenem]

, 2010
Doripenem is the newest addition to the carbapenems, the most active class of antibiotics against many resistant pathogens. This review focuses on the antimicrobial, pharmacological and clinical aspects of doripenem.
KORTEN, VOLKAN
core   +2 more sources

Klebsiella pneumoniae Susceptibility to Carbapenem/Relebactam Combinations: Influence of Inoculum Density and Carbapenem-to-Inhibitor Concentration Ratio

Biomedicines, 2022
The inoculum effect (IE) is a well-known phenomenon with beta-lactams. At the same time, the IE has not been extensively studied with carbapenem/carbapenemase inhibitor combinations.
Maria V. Golikova, Kamilla N. Alieva, Alla V. Filimonova, Vladimir A. Ageevets, Ofeliia S. Sulian, Alisa A. Avdeeva, Sergey V. Sidorenko, Stephen H. Zinner   +7 more
doaj   +1 more source