Results 51 to 60 of about 5,549 (198)

Aetiology and Antibiotic Susceptibility of Common Bacterial Infections in Hospitalised Patients: A 2019 Multisite Cross‐Sectional Survey in Jakarta, Indonesia

Tropical Medicine &International Health, Volume 31, Issue 9, Page 1231-1237, September 2026.
ABSTRACT Objectives To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia. Methods We conducted a hospital‐wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment.
Justin de Brabander, Erni J. Nelwan, Ralalicia Limato, Monik Alamanda, Manzilina Mudia, Enty Tjoa, Ifael Y. Mauleti, Maria Mayasari, Iman Firmansyah, T. Mannaria Jayati, Michèle van Vugt, H. Rogier van Doorn, Raph L. Hamers, Erni J. Nelwan, Ralalicia Limato, Manzilina Mudia, Monik Alamanda, Helio Guterres, Enty Enty, Y. Ifael, Maria Mayasari Mauleti, Iman Firmansyah, May Hizrani, Anis Karuniawati, Taralan Tambunan, Amin Soebandrio, Decy Subekti, Iqbal Elyazar, Mutia Rahardjani, Fitria Wulandari, Reinout van Crevel, H. Rogier van Doorn, Vu Thi Lan Huong, Nga Do Ti Thuy, Sonia Lewycka, Alex Broom, Raph L. Hamers   +36 more
wiley   +1 more source

Specific variants in ftsI reduce carbapenem susceptibility in Pseudomonas aeruginosa

Microbiology Spectrum
The ftsI locus of gram-negative bacteria encodes penicillin-binding protein 3 (PBP3), a common target of β-lactam antibiotics. Recent genomic surveillance of carbapenem-resistant Pseudomonas aeruginosa revealed that 17% of strains possessed nonsynonymous
Hirokazu Yano, Noboru Nakata, Koji Yahara, Motoyuki Sugai, Yukari Sato   +4 more
doaj   +1 more source

Aeromonas dhakensis: Clinical Isolates with High Carbapenem Resistance

Pathogens, 2022
Aeromonas dhakensis is ubiquitous in aquatic habitats and can cause life-threatening septicaemia in humans. However, limited data are available on their antimicrobial susceptibility testing (AST) profiles.
Suat Moi Puah, Wei Ching Khor, Kyaw Thu Aung, Tien Tien Vicky Lau, S. D. Puthucheary, Kek Heng Chua   +5 more
doaj   +1 more source

Characterization of Multitrait Plant Growth‐Promoting Rhizobacteria From Opuntia ficus‐indica in Different Moroccan Climates

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The rhizosphere of Opuntia ficus‐indica from different Moroccan climates harbors diverse plant growth‐promoting bacteria with multiple beneficial traits. Selected isolates enhanced seed germination and seedling growth, highlighting their potential for sustainable agriculture in arid and semiarid environments.
Ilham Zouitane, Daniela Cristina Campana, Patrizia Cesaro, Nadia Massa, Giorgia Novello, Elisa Gamalero, Valeria Todeschini, Mohamed Ferioun, Khalid Derraz, Saad Ibnsouda Koraichi, Naïma El Ghachtouli, Guido Lingua   +11 more
wiley   +1 more source

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

The doripenem serum concentrations in intensive care patients suffering from acute kidney injury, sepsis, and multi organ dysfunction syndrome undergoing continuous renal replacement therapy slow low-efficiency dialysis

Drug Design, Development and Therapy, 2014
Andrzej Wieczorek, Andrzej Tokarz, Wojciech Gaszynski, Tomasz Gaszynski Department of Anesthesiology and Intensive Therapy, Medical University of Lodz, Lodz, Poland Abstract: Doripenem is a novel wide-spectrum antibiotic, and a derivate of carbapenems.
Wieczorek A, Tokarz A, Gaszynski W, Gaszynski T   +3 more
doaj  

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, Volume 21, Issue 5, Page 477-486, May 2026.
Visual Abstract Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

Rethinking urinary antibiotic breakpoints: analysis of urinary antibiotic concentrations to treat multidrug resistant organisms

BMC Research Notes, 2018
Objective The present study analyzed whether renally eliminated antibiotics achieve sufficient urinary concentrations based on their pharmacokinetic/pharmacodynamic principles to effectively eradicate organisms deemed resistant by automated ...
Daniel B. Chastain, S. Travis King, Kayla R. Stover   +2 more
doaj   +1 more source

Epidemiology, Management, and Alarmingly High Mortality of Burn Patients: A Retrospective Analysis From a Resource‐Limited Tertiary Centre in Syria

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Burn injuries pose a significant challenge in resource‐limited settings, particularly during humanitarian crises. This study examines the epidemiology, management, and outcomes of burn patients at a tertiary hospital in Damascus, Syria, from 2021 to 2024.
Lorieh Domat, Adel Azar, Ahmad Alkheder, Diana Mohammad, Jean Domat, Hanady Zwaraa, Rawnak Almidani   +6 more
wiley   +1 more source

Actividad in vitro de doripenem comparado con meropenem frente a aislamientos de Pseudomonas aeruginosa en un centro asistencial de tercer nivel de Bogotá (Colombia) Activity of Doripenem compared to Meropenem against Pseudomonas aeruginosa isolates at Tertiary Care Teaching Hospital in Bogotá (Colombia)

Infectio, 2012
Objetivo: El objetivo de este estudio fue evaluar la actividad in vitro de doripenem comparado con meropenem frente a aislamientos locales de Pseudomonas aeruginosa (P. aeruginosa) .
Adriana Jiménez, Claudia Fajardo
doaj