Results 71 to 80 of about 6,860 (236)

In Vitro Activity of Doripenem compared to Meropenem against Pseudomonas aeruginosa isolates at Tertiary Care Teaching Hospital in Bogotá (Colombia) [PDF]

, 2021
Objetivo: El objetivo de este estudio fue evaluar la actividad in vitro de doripenem comparado con meropenem frente a aislamientos locales de Pseudomonas aeruginosa (P. aeruginosa). Materiales y métodos: En el Hospital San José de Bogotá (Colombia), un
Fajardo, Claudia, Jiménez, Adriana
core  

Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley   +1 more source

Structural Characterization and Functional Annotation of Hypothetical Proteins in the Multidrug‐Resistant Strains of Pseudomonas aeruginosa

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Pseudomonas aeruginosa is a leading cause of severe nosocomial infections worldwide. This opportunistic pathogen is associated with increased morbidity and mortality rates due to its high levels of antibiotic resistance. The identification of novel therapeutic targets is therefore a pressing global health priority.
Fatemeh Nasiri Khoonsari, Zahra Zafari, Bufu Tang   +2 more
wiley   +1 more source

In vivo efficacy of doripenem (DRPM) against Pseudomonas aeruginosa in murine chronic respiratory tract infection model

, 2011
Doripenem is a carbapenem antibiotic with broad-spectrum coverage of gram-positive and gram-negative bacteria, including Pseudomonas aeruginosa, and is considered to be as effective as meropenem.
Yamada, Koichi, Nobuko Araki, Yasuaki Yamada, Kamihira, Shimeru, Koichi Yamada, Araki, Nobuko, Yamada, Yasuaki, Yanagihara, Katsunori, Kohno, Shigeru, Shigeru Kohno, Yoshitomo Morinaga, Katsunori Yanagihara, Shimeru Kamihira, Morinaga, Yoshitomo   +13 more
core   +1 more source

An Investigation of Colistin Heteroresistance in Klebsiella pneumoniae Isolates in Iran

BioMed Research International, Volume 2026, Issue 1, 2026.
Background According to the World Health Organization 2024 bacterial priority pathogens list, carbapenem‐resistant Enterobacterales (CRE) were listed among the critical priority pathogens. Heteroresistance (i.e., a bacterial isolate that appears susceptible but harbors resistant subpopulations) represents a challenge in traditional laboratory testing ...
Zohreh Riahi Rad, Zahra Riahi Rad, Hossein Goudarzi, Mehdi Goudarzi, Mohsen Javidi, Javad Yasbolaghi Sharahi, Masoud Kargar, Ali Hashemi, Baisakhi Banerjee   +8 more
wiley   +1 more source

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae

Frontiers in Cellular and Infection Microbiology, 2018
Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which
Tania Cebrero-Cangueiro, R. Álvarez-Marín, Gema Labrador-Herrera, Y. Smani, Elisa Cordero-Matía, J. Pachón, M. E. Pachón-Ibáñez   +6 more
semanticscholar   +1 more source

[Risk of Acute Kidney Injury in Patients Treated with Vancomycin and Piperacillin/Tazobactam Compared to Vancomycin and Meropenem or Doripenem: A Retrospective Cohort Study].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019
It has been reported that the risk of acute kidney injury (AKI) is higher during treatment with vancomycin and piperacillin/tazobactam compared to use of vancomycin and cefepim or meropenem.
Naohito Ide, Seitaro Sato, Kazuyo Sawaguchi   +2 more
semanticscholar   +1 more source

Association of doripenem resistance with OXA-type carbapenemases in Acinetobacter baumannii isolates [PDF]

, 2016
Conclusion: The bla(OXA-23) and bla(OXA-58) gene combinations may confer resistance with a much greater MIC of both meropenem and doripenem.
Gulsah Asik, Engin Karakece, Huseyin-Agah Terzi, Atasoy, Ali Rıza, Aykan, Şadiye Berna, Çiftci, İhsan Hakkı   +5 more
core   +1 more source

Bloodstream Infection Caused by Carbapenemase‐Producing Enterobacterales in a Tertiary Hospital of Colombia: A 6 Year Retrospective Study

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background The global spread of carbapenemase‐producing Enterobacterales (CPE) has emerged as a significant public health challenge. However, epidemiological studies on CPE infections in Latin America remain scarce. This study aims to characterize bloodstream infections (BSIs) caused by CPE at a tertiary hospital over a 6‐year period and analyze the ...
Juan David Cáceres-González, Jorge Álvarez, Lorena Matta-Cortés, Ernesto Martínez-Buitrago, Johann A. Ospina-Galindez, Claudia C. Paredes-Amaya, Bishnu P. Marasini   +6 more
wiley   +1 more source

Synergistic Effects of Amikacin With Imipenem and Ciprofloxacin Against Multidrug‐Resistance Uropathogenic Escherichia coli

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Introduction There are limited therapeutic options available for treating aminoglycoside‐ and carbapenem‐resistant Gram‐negative bacteria. Therefore, there is an urgent need for novel effective antimicrobial agents. Numerous studies have reported the enhanced efficacy of antibiotic combinations against multidrug‐resistant (MDR) strains compared to ...
Sahar Sadr Moharerpour, Fatemeh Ahmadi Parviji, Kasra Javadi, Mehrdad Halaji, Shweta Negi   +4 more
wiley   +1 more source