Results 61 to 70 of about 6,509 (249)

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Toxicity of antiglaucoma drugs with and without benzalkonium chloride to cultured human corneal endothelial cells [PDF]

, 2010
Masahiko Ayaki1, Atsuo Iwasawa2, Yoichi Inoue31Department of Ophthalmology, Saitama National Hospital, Wako, Japan; 2Life Particle Interaction Engineering Creation, New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan; 3Department of ...
Ayaki, Masahiko, Inoue, Yoichi, Iwasawa, Atsuo   +2 more
core   +3 more sources

A New Ocular Phenotype Combining Juvenile Glaucoma and Doyne Honeycomb Retinal Dystrophy (Malattia Leventinese) due to a Novel EFEMP1 Pathogenic Variant

American Journal of Medical Genetics Part A, Volume 197, Issue 1, January 2025.
ABSTRACT Doyne honeycomb retinal dystrophy (DHRD), also termed malattia leventinese (MLVT), is a dominantly inherited ocular disease characterized by the progressive accumulation of macular and peripapillary drusenoid material beneath the retinal pigment epithelium in the Bruch membrane.
Oscar F. Chacon‐Camacho, Thania Ordaz‐Robles, Marion A. Cid‐García, Olivia Yepes‐Rodríguez, Rocio Arce‐González, Alan Martínez‐Aguilar, Juan Carlos Zenteno   +6 more
wiley   +1 more source

Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension [PDF]

, 2009
Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol has a favorable safety profile, with an incidence of ocular burning and stinging
Beckers, Henny JM, Schouten, Jan SAG, Webers, Carroll AB   +2 more
core   +2 more sources

Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma. [PDF]

, 2008
PURPOSE. To evaluate the effect of the timolol-dorzolamide fixed combination (TDFC) and latanoprost 0.005% on 24-hour intraocular pressure (IOP), systolic (SBP) and diastolic (DBP) blood pressure, and diastolic ocular perfusion pressure (DOPP) in ...
Floriani I., Konstas A.G.P., Miglior S., Pizzolante T., Quaranta L.   +4 more
core   +1 more source

The carbonic anhydrase enzymes as new targets for the management of neglected tropical diseases

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
The scientific literature dealing with the identification and development of selective inhibitors of the carbonic anhydrases expressed by the protozoans Trypanosoma cruzi (T. cruzi) and Leishmania spp. is reviewed and analyzed, with the aim to sustain the validation process of new classes of drugs useful for the management of neglected tropical ...
Gioele Renzi, Federico Ladu, Fabrizio Carta, Claudiu T. Supuran   +3 more
wiley   +1 more source

Ocular hypotensive effects of a Rho-associated protein kinase inhibitor in rabbits

Clinical Ophthalmology, 2017
Muhammad Irfan Kamaruddin,1,2 Momoko Nakamura-Shibasaki,1 Yu Mizuno,1 Yoshiaki Kiuchi1 1Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan; 2Department of Ophthalmology ...
Kamaruddin MI, Nakamura-Shibasaki M, Mizuno Y, Kiuchi Y   +3 more
doaj  

Equine uveitis: Outcome and adverse effects after one or two intravitreal low‐dose gentamicin injections

Equine Veterinary Journal, Volume 57, Issue 1, Page 160-168, January 2025.
Abstract Background Uveitis is common in horses, potentially turning chronic (persistent or recurrent) resulting in impaired vision or blindness. All mainstay therapeutics aims at controlling inflammation, but long‐term or lifelong treatment is often needed with possibly severe side effects.
S. Morén, M. Kallberg, L. Strom
wiley   +1 more source

Efeitos maleato de timolol 0.5% do cloridrato de dorzolamida 2%, e da associação de ambas na pressão intra-ocular Efficacy of timolol maleate 0.5% dorzolamide hydrochloride 2%, and the combination of both drugs on intraocular pressure

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Avaliaram-se efeitos da dorzolamida do timolol e da combinação de ambos sobre pressão intra-ocular (PIO) de cães normais, além de alterações no olho contralateral, não-tratado.
A.G. Borges, C.V.S. Brandão, J.J.T. Ranzani, J.C. Adalberto   +3 more
doaj   +1 more source

In Silico Pharmacological and Pharmacokinetic Study of Marmeline From Bael Fruit for the Treatment of Alzheimer’s Disease

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Epidemiological studies identify risk factors for Alzheimer’s disease (AD), which induces oxidative stress and inflammation. Pharmaceuticals aimed against the nuclear receptor PPARγ, including TZDs, have been associated with considerable negative consequences in AD treatment.
Tassanee Ongtanasup, Onkamon Jampa, Nattawan Suwannakul, Komgrit Eawsakul, Benedetto Natalini   +4 more
wiley   +1 more source