Results 131 to 140 of about 1,171,051 (326)

Evolution under fluctuating environments explains observed robustness in metabolic networks [PDF]

open access: yes, 2010
A high level of robustness against gene deletion is observed in many organisms. However, it is still not clear which biochemical features underline this robustness and how these are acquired during evolution.
Pfeiffer, Thomas, Soyer, Orkun S.
core   +2 more sources

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang   +12 more
wiley   +1 more source

Dosage-sensitive molecular mechanisms are associated with the tissue-specificity of traits and diseases

open access: yesComputational and Structural Biotechnology Journal, 2020
Hereditary diseases and complex traits often manifest in specific tissues, whereas their causal genes are expressed in many tissues that remain unaffected.
Juman Jubran   +3 more
doaj   +1 more source

Chromosomal control of wheat endosperm proteins. A critical review. [PDF]

open access: yes, 1977
Progress made in the chromosomal location of structural genes for wheat endosperm proteins, and in the study of the regulation and quantitative expression of these genes, by using aneuploids and by related techniques, is critically evaluated ...
Aragoncillo Ballesteros, Cipriano   +3 more
core   +2 more sources

Dichotomy of Dosage Compensation along the Neo Z Chromosome of the Monarch Butterfly.

open access: yesCurrent Biology, 2019
Mechanisms of sex chromosome dosage compensation (SCDC) differ strikingly among animals. In Drosophila flies, chromosome-wide transcription is doubled from the single X chromosome in hemizygous (XY) males, whereas in Caenorhabditis nematodes, expression ...
Liuqi Gu   +5 more
semanticscholar   +1 more source

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

open access: yesAdvanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee   +4 more
wiley   +1 more source

Conserved microRNA targeting reveals preexisting gene dosage sensitivities that shaped amniote sex chromosome evolution [PDF]

open access: yes, 2017
Mammalian X and Y Chromosomes evolved from an ordinary autosomal pair. Genetic decay of the Y led to X Chromosome inactivation (XCI) in females, but some Y-linked genes were retained during the course of sex chromosome evolution, and many X-linked genes ...
Bellott, Daniel W.   +3 more
core   +1 more source

Parallel 3D Bioprinting on SLIPS‐Microarrays

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg   +3 more
wiley   +1 more source

Dynamics of X chromosome hyper-expression and inactivation in male tissues during stick insect development.

open access: yesPLoS Genetics
Differentiated sex chromosomes are frequently associated with major transcriptional changes: the evolution of dosage compensation (DC) to equalize gene expression between the sexes and the establishment of meiotic sex chromosome inactivation (MSCI).
Jelisaveta Djordjevic   +11 more
doaj   +1 more source

Sex-dimorphic gene expression and ineffective dosage compensation of Z-linked genes in gastrulating chicken embryos

open access: yesBMC Genomics, 2010
Background Considerable progress has been made in our understanding of sex determination and dosage compensation mechanisms in model organisms such as C. elegans, Drosophila and M. musculus.
Mathur Sachin   +4 more
doaj   +1 more source

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