Results 41 to 50 of about 8,241,341 (344)

Shift work and ischaemic heart disease: meta-analysis and dose-response relationship.

Occupational Medicine, 2019
BACKGROUND Shift work is common in many industries. The potential association between shift work and ischaemic heart disease (IHD) remains controversial.
M. Cheng, Heng He, Dongming Wang, Luli Xu, Bin Wang, K. M. Ho, Weihong Chen   +6 more
semanticscholar   +1 more source

Initial Approach to the Cellular Irradiation Injury of Human Pancreatic Carcinoma Cell Line MIA PaCa-2 by High Dose per Fraction

Cancer Biology & Medicine, 2010
OBJECTIVE To investigate an initial approach of radiotherapy, which produces cellular radiation injury by high dose in one fraction. METHODS Human pancreatic carcinoma cell line MIA PaCa-2, was cultivated and divided into 5 groups: 0, 2, 5, 10, 17 ...
Ping WANG, Hai-li YU, Zhi-yong YUAN, Zhi-zhen WANG   +3 more
doaj   +1 more source

Model Selection versus Model Averaging in Dose Finding Studies [PDF]

, 2015
Phase II dose finding studies in clinical drug development are typically conducted to adequately characterize the dose response relationship of a new drug.
Bornkamp, Björn, Bretz, Frank, Dette, Holger, Schorning, Kirsten   +3 more
core   +2 more sources

Additional file 4: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Study quality of case-control studies included in the analysis of sleep duration and cancer risk. (DOCX 20 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

The relationship between zinc intake and serum/plasma zinc concentration in adults: a systematic review and dose–response meta-analysis by the EURRECA Network [PDF]

, 2012
Dietary zinc recommendations vary widely across Europe due to the heterogeneity of pproaches used by expert panels. Under the EURRECA consortium a protocol was designed to systematically review and undertake meta-analyses of research data to create a ...
Anna-Louise Stammers, Carla Dullemeijer, Higgins, Lluis Serra-Majem, Mariela Nissensohn, Marisol Warthon Medina, Nicola M. Lowe, Olga W. Souverein, Sujata Patel, Victoria Hall Moran   +9 more
core   +2 more sources

A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe

Frontiers in Pharmacology, 2021
Aims: Cardiovascular outcome trials with anti-diabetic drugs suggest that additional cardiovascular benefit can be achieved independent of improving glycaemic control.
Jeroen V. Koomen, Jeroen V. Koomen, Jasper Stevens, Margje H. Monster-Simons, Margje H. Monster-Simons, Hiddo J. L. Heerspink, Peter G. M. Mol, Peter G. M. Mol   +7 more
doaj   +1 more source

Additional file 1: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
PRISMA 2009 Checklist. (DOCX 25 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Dose-response relationship between dietary magnesium intake, serum magnesium concentration and risk of hypertension: a systematic review and meta-analysis of prospective cohort studies

Nutrix Journal, 2017
BackgroundThe findings of prospective cohort studies are inconsistent regarding the association between dietary magnesium intake and serum magnesium concentration and the risk of hypertension.
Hedong Han, X. Fang, Xin Wei, Yuzhou Liu, Z. Jin, Qi Chen, Z. Fan, J. Aaseth, A. Hiyoshi, Jia He, Yang Cao   +10 more
semanticscholar   +1 more source

Additional file 2: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Characteristics of studies included in the meta-analysis. (DOCX 39 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Tooth Loss Is Associated With Increased Risk of Dementia and With a Dose-Response Relationship

Frontiers in Aging Neuroscience, 2018
Objective: Both tooth loss and dementia are age-related and frequently-occurring diseases. Increasing attention has been given to explore the pathogenesis related to oral-brain function disorders.
Jun Chen, Chang-Ju Ren, Lan Wu, Ling-yun Xia, Jun Shao, Wei-dong Leng, Xian-Tao Zeng   +6 more
semanticscholar   +1 more source