Results 41 to 50 of about 8,528,698 (291)

Model Selection versus Model Averaging in Dose Finding Studies [PDF]

, 2015
Phase II dose finding studies in clinical drug development are typically conducted to adequately characterize the dose response relationship of a new drug.
Bornkamp, Björn, Bretz, Frank, Dette, Holger, Schorning, Kirsten   +3 more
core   +2 more sources

Initial Approach to the Cellular Irradiation Injury of Human Pancreatic Carcinoma Cell Line MIA PaCa-2 by High Dose per Fraction

Cancer Biology & Medicine, 2010
OBJECTIVE To investigate an initial approach of radiotherapy, which produces cellular radiation injury by high dose in one fraction. METHODS Human pancreatic carcinoma cell line MIA PaCa-2, was cultivated and divided into 5 groups: 0, 2, 5, 10, 17 ...
Ping WANG, Hai-li YU, Zhi-yong YUAN, Zhi-zhen WANG   +3 more
doaj   +1 more source

Additional file 4: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Study quality of case-control studies included in the analysis of sleep duration and cancer risk. (DOCX 20 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Dose-response relationship between dietary magnesium intake, serum magnesium concentration and risk of hypertension: a systematic review and meta-analysis of prospective cohort studies

Nutrix Journal, 2017
BackgroundThe findings of prospective cohort studies are inconsistent regarding the association between dietary magnesium intake and serum magnesium concentration and the risk of hypertension.
Hedong Han, X. Fang, Xin Wei, Yuzhou Liu, Zhicao Jin, Qi Chen, Z. Fan, J. Aaseth, A. Hiyoshi, Jia He, Yang Cao   +10 more
semanticscholar   +1 more source

Additional file 1: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
PRISMA 2009 Checklist. (DOCX 25 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

The relationship between zinc intake and serum/plasma zinc concentration in adults: a systematic review and dose–response meta-analysis by the EURRECA Network [PDF]

, 2012
Dietary zinc recommendations vary widely across Europe due to the heterogeneity of pproaches used by expert panels. Under the EURRECA consortium a protocol was designed to systematically review and undertake meta-analyses of research data to create a ...
Anna-Louise Stammers, Carla Dullemeijer, Higgins, Lluis Serra-Majem, Mariela Nissensohn, Marisol Warthon Medina, Nicola M. Lowe, Olga W. Souverein, Sujata Patel, Victoria Hall Moran   +9 more
core   +2 more sources

Additional file 5: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Sensitivity analysis of sleep duration and cancer risk, shortest vs. reference analysis. (PDF 194 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Dose-Response Relationship of Neuromuscular Training for Injury Prevention in Youth Athletes: A Meta-Analysis

Frontiers in Physiology, 2017
Background: Youth athletes with intensive sports participation are at an increased risk of sustaining injuries. Neuromuscular training programs reduce sports-related injury risk in this population, however, the dose-response relationship is largely ...
S. Steib, A. Rahlf, K. Pfeifer, A. Zech
semanticscholar   +1 more source

Preclinical Evaluation of Botulinum Toxin Type E (TrenibotulinumtoxinE) Using the Mouse Digit Abduction Score (DAS) Assay

Toxins
TrenibotulinumtoxinE (trenibotE), a botulinum neurotoxin serotype E (BoNT/E), is being developed for clinical use, and can fill a unique treatment gap for patients who are seeking neurotoxin treatment with a rapid onset and short duration of effect. This
Gregory S. Nicholson, David Canty, Annemarie Southern, Kevin Whelan, Amy D. Brideau-Andersen, Ron S. Broide   +5 more
doaj   +1 more source

Adverse effects of long term, continual administration of high doses of albendazole in the treatment of echinococcal disease [PDF]

Vojnosanitetski Pregled, 2008
Background/Aim. Modern treatment of cystic echinococcosis, except for surgical treatment and percutaneous drainage of cyst considers also administration of albendazole as a type of individual therapy.
Jevtić Miodrag, Mikić Dragan, Arsić-Komljenović Gordana, Stanković Nebojša, Ristanović Elizabeta, Sjeničić Goran, Janićijević-Hudomal Snežana   +6 more
doaj   +1 more source