Results 51 to 60 of about 8,423,709 (341)

Additional file 5: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Sensitivity analysis of sleep duration and cancer risk, shortest vs. reference analysis. (PDF 194 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Preclinical Evaluation of Botulinum Toxin Type E (TrenibotulinumtoxinE) Using the Mouse Digit Abduction Score (DAS) Assay

Toxins
TrenibotulinumtoxinE (trenibotE), a botulinum neurotoxin serotype E (BoNT/E), is being developed for clinical use, and can fill a unique treatment gap for patients who are seeking neurotoxin treatment with a rapid onset and short duration of effect. This
Gregory S. Nicholson, David Canty, Annemarie Southern, Kevin Whelan, Amy D. Brideau-Andersen, Ron S. Broide   +5 more
doaj   +1 more source

Additional file 2: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Characteristics of studies included in the meta-analysis. (DOCX 39 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Shrinkage estimation for dose-response modeling in phase II trials with multiple schedules

, 2020
Recently, phase II trials with multiple schedules (frequency of administrations) have become more popular, for instance in the development of treatments for atopic dermatitis.
Friede, Tim, Günhan, Burak Kürsad, Meyvisch, Paul   +2 more
core   +1 more source

Sugammadex ED90 dose to reverse the rocuronium neuromuscular blockade in obese patients

Revista do Colégio Brasileiro de Cirurgiões
Objective: to determine the ED90 (minimum effective dose in 90% of patients) of sugammadex for the reversal of rocuronium-induced moderate neuromuscular blockade (NMB) in patients with grade III obesity undergoing bariatric surgery.
MAURO PRADO DA SILVA, CHRISTIANO MATSUI, DANIEL DONGIOU KIM, JOAQUIM EDSON VIEIRA, CARLOS ALBERTO MALHEIROS, LIGIA ANDRADE SILVA TELLES MATHIAS   +5 more
doaj   +1 more source

Additional file 3: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Study quality of cohort studies included in the analysis of sleep duration and cancer risk. (DOCX 21 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

Dose-response relationship between dietary magnesium intake, serum magnesium concentration and risk of hypertension: a systematic review and meta-analysis of prospective cohort studies

Nutrix Journal, 2017
BackgroundThe findings of prospective cohort studies are inconsistent regarding the association between dietary magnesium intake and serum magnesium concentration and the risk of hypertension.
Hedong Han, X. Fang, Xin Wei, Yuzhou Liu, Z. Jin, Qi Chen, Z. Fan, J. Aaseth, A. Hiyoshi, Jia He, Yang Cao   +10 more
semanticscholar   +1 more source

A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe

Frontiers in Pharmacology, 2021
Aims: Cardiovascular outcome trials with anti-diabetic drugs suggest that additional cardiovascular benefit can be achieved independent of improving glycaemic control.
Jeroen V. Koomen, Jeroen V. Koomen, Jasper Stevens, Margje H. Monster-Simons, Margje H. Monster-Simons, Hiddo J. L. Heerspink, Peter G. M. Mol, Peter G. M. Mol   +7 more
doaj   +1 more source

Additional file 6: of Sleep duration and the risk of cancer: a systematic review and meta-analysis including doseâ response relationship

, 2018
Sensitivity analysis of sleep duration and cancer risk, longest vs. reference analysis. (PDF 186 kb)
Chen, Yuheng, Tan, Fengwei, Wei, Luopei, Li, Xin, Lyu, Zhangyan, Feng, Xiaoshuang, Wen, Yan, Guo, Lanwei, He, Jie, Dai, Min, Li, Ni   +10 more
openaire   +1 more source

The association between perceived stress and mortality among people with multimorbidity: a prospective population-based cohort study [PDF]

, 2016
Multimorbidity is common and is associated with poor mental health and high mortality. Nevertheless, no studies have evaluated whether mental health may affect the survival of people with multimorbidity.
Christensen, Kaj Sparle, Fenger-Grøn, Morten, Larsen, Finn Breinholt, Larsen, Karen Kjær, Mercer, Stewart W., Nielsen, Marie Germund, Prior, Anders, Robinson, Kirstine Magtengaard, Vestergaard, Mogens   +8 more
core   +1 more source