Results 21 to 30 of about 34,802 (246)

The Aftermath of Tapering Tocilizumab After Achieving Treatment Target in Patients With Rheumatoid Arthritis: A Nationwide Cohort Study

Frontiers in Medicine, 2022
BackgroundAlthough recent guidelines recommend that tapering of biologic disease-modifying anti-rheumatic drugs (bDMARDs) can be considered in patients with rheumatoid arthritis (RA), there has been little evidence supporting the strategy during the non ...
Jun Won Park, Min Jung Kim, Hyoun-Ah Kim, Jin Hyun Kim, Eun Bong Lee, Kichul Shin   +5 more
doaj   +1 more source

AB0695 Dose tapering of infiximab in patients with spondyloarthritis [PDF]

Annals of the Rheumatic Diseases, 2017
Background Infliximab have proven to be effective in spondyloarthritis. Previous studies suggest that patients in clinical remission may benefit from dose reduction or pharmacological tapering without relapse. Objectives To study the evolution of clinical activity and physical function in patients with spondyloarthritis, ankylosing spondylitis (AS ...
M Correyero, JC Nieto, CM González, A Lόpez, R González, C Saenz, L García-Montoya, FJL Longo, I Monteagudo   +8 more
openaire   +1 more source

Clinical factors predicting the successful discontinuation of hormone replacement therapy in patients diagnosed with primary hypothyroidism.

PLoS ONE, 2020
BACKGROUND:Although reversible in some patients, primary hypothyroidism is considered a permanent condition requiring lifelong hormone therapy. This study aimed to investigate the factors predicting the successful discontinuation of levothyroxine (L-T4 ...
Kyong Yeun Jung, Hana Kim, Hoon Sung Choi, Jee Hyun An, Sun Wook Cho, Hyo Jeong Kim, Young Joo Park   +6 more
doaj   +1 more source

Dose tapering for ciclosporin in cats with nonflea‐induced hypersensitivity dermatitis [PDF]

Veterinary Dermatology, 2013
BackgroundLittle information is available on the ciclosporin dose‐tapering regimen and clinical response in the treatment of feline hypersensitivity dermatitis.Hypothesis/ObjectivesTo test a dose‐tapering regimen and assess efficacy and clinical safety for up to 18 weeks.AnimalsEighty‐eight client‐owned cats with feline hypersensitivity dermatitis ...
Jean, Steffan, Elizabeth, Roberts, Andrea, Cannon, Pascal, Prélaud, Peter, Forsythe, Jacques, Fontaine, Stephen, King, Wolfgang, Seewald   +7 more
openaire   +2 more sources

Using real-world data to dynamically predict flares during tapering of biological DMARDs in rheumatoid arthritis: development, validation, and potential impact of prediction-aided decisions

Arthritis Research & Therapy, 2022
Background Biological disease-modifying antirheumatic drugs (bDMARDs) are effective in the treatment of rheumatoid arthritis. However, as bDMARDs may also lead to adverse events and are expensive, tapering them is of great clinical interest.
Matthijs S. van der Leeuw, Marianne A. Messelink, Janneke Tekstra, Ojay Medina, Jaap M. van Laar, Saskia Haitjema, Floris Lafeber, Josien J. Veris-van Dieren, Marlies C. van der Goes, Alfons A. den Broeder, Paco M. J. Welsing   +10 more
doaj   +1 more source

Optimizing treatment with tumour necrosis factor inhibitors in rheumatoid arthritis—a proof of principle and exploratory trial: is dose tapering practical in good responders? [PDF]

Rheumatology, 2017
Fowzia Ibrahim, Caroline J Dore, Ailsa Bosworth   +2 more
exaly   +2 more sources

Lowering Expectations: Glucocorticoid Tapering Among Veterans With Rheumatoid Arthritis Achieving Low Disease Activity on Stable Biologic Therapy

ACR Open Rheumatology, 2023
Objective In the Steroid EliMination In Rheumatoid Arthritis (SEMIRA) trial, 65% of patients with rheumatoid arthritis (RA) in low disease activity (LDA) on stable biologic therapy successfully tapered glucocorticoids.
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Jorge Rojas, Brian C. Sauer, Punyasha Roul, Gary A. Kunkel, Tawnie J. Braaten, Alison Petro, Ted R. Mikuls, Grant W. Cannon   +10 more
doaj   +1 more source

Longitudinal Dose Trajectory Among Patients Tapering Long-Term Opioids

Pain Medicine, 2021
Abstract Objective To evaluate the dose trajectory of new opioid tapers and estimate the percentage of patients with sustained tapers at long-term follow-up. Design Retrospective cohort study.
Joshua J Fenton, Elizabeth M Magnan, Alicia L Agnoli, Stephen G Henry, Guibo Xing, Daniel J Tancredi   +5 more
openaire   +2 more sources

Fixed tapering dosage of acitretin in patients with psoriasis: A short-term analysis of clinical efficacy and its effects on biochemical parameters

Indian Journal of Dermatology, 2019
Background: Acitretin is a widely used systemic retinoid in the treatment of psoriasis. Dosage of acitretin in not weight adjusted due to certain interindividual variations.
Varadraj V Pai, Diksha Phadke, Pankaj Shukla, Krupeksha Naik   +3 more
doaj   +1 more source

Implementing gradual, hyperbolic tapering of long-acting injectable antipsychotics by prolonging the inter-dose interval: an modelling study

Therapeutic Advances in Psychopharmacology, 2023
Gradual, hyperbolic tapering has been proposed as a method to reduce the risk of withdrawal effects and potential relapse of an underlying condition by minimising disruption of existing equilibria.
James R. O’Neill, David M. Taylor, Mark A. Horowitz   +2 more
doaj   +1 more source