Results 61 to 70 of about 1,047,229 (199)

Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]

open access: yes, 1990
We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M.   +1 more
core  

Zn-Al LAYERED DOUBLE HYDROXIDE AS HOST MATERIAL FOR SUNSCREEN COMPOUND OF p-AMINOBENZOIC ACID

open access: yesIndonesian Journal of Chemistry, 2010
Zn-Al layered double hydroxide can be used as host material for UV active compound p-aminobenzoic acid (PABA), which is having capability to block UV light of sunlight.
Roto Roto, Iqmal Tahir, Mustofa Mustofa
doaj   +1 more source

Techniques to optimize post-embedding single and double staining for amino acid neurotransmitters. [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1992
We report a number of technical refinements for single and double staining with post-embedding electron microscopy for glutamate, aspartate, and gamma-aminobutyric acid. Best results were obtained with 2.5% glutaraldehyde in the fixative and by minimizing the duration of plastic polymerization and the interval between cutting and reacting ...
K D, Phend, R J, Weinberg, A, Rustioni
openaire   +2 more sources

DNA Renaturation at the Water-Phenol Interface [PDF]

open access: yes, 2003
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
121   +161 more
core   +4 more sources

Dynamic crosstalk between amino acid metabolism and cancer drug efficacy: From mechanisms to therapeutic opportunities

open access: yesiScience
Summary: Cancer, driven by genomic instability, is profoundly influenced by DNA damage and repair mechanisms. Double-strand breaks (DSBs), repaired via homologous recombination (HR), and non-homologous end joining (NHEJ), are critical for genomic ...
Mengyi Zhu, Changping Wang, Dianwen Song
doaj   +1 more source

Low level sequence variant analysis of recombinant proteins: an optimized approach.

open access: yesPLoS ONE, 2012
Sequence variants in recombinant biopharmaceuticals may have a relevant and unpredictable impact on clinical safety and efficacy. Hence, their sensitive analysis is important throughout bioprocess development.
Anne Zeck   +10 more
doaj   +1 more source

Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial

open access: yesCritical Care, 2022
Background A defining feature of prolonged critical illness is muscle wasting, leading to impaired recovery. Supplementation with a tailored blend of amino acids may bolster the innate gut defence, promote intestinal mucosa repair and limit muscle loss ...
Nicholas Heming   +21 more
doaj   +1 more source

Synthesis of PNA Oligoether Conjugates

open access: yesMolecules, 2014
Several different approaches have been explored for conjugation of oligoethers to PNA with internally or N-terminal placed diaminopropionic acid residues.
Alice Ghidini   +3 more
doaj   +1 more source

Different characteristics of 40 kinds of free amino acids and 5-amino levulinic acid between wines and sakes (Japanese rice wines)

open access: yesJournal of Future Foods
Based on a systemic analysis for the global burden of disease study from 1990 to 2016, the Global Burden of Diseases (GBD) 2016 Alcohol Collaborators reported that alcohol use was a leading risk factor for global disease burden and caused substantial ...
Tohru Kimura
doaj   +1 more source

Engineering Dehydrated Amino Acid Residues in the Antimicrobial Peptide Nisin [PDF]

open access: yes, 1992
The small antimicrobial peptide nisin, produced by Lactococcus lactis, contains the uncommon amino acid residues dehydroalanine and dehydrobutyrine and five thio ether bridges.
Boot, Hein J.,   +5 more
core   +1 more source

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