Results 61 to 70 of about 2,123,623 (331)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Thermal regime of coastal waters and possible mechanisms of formation for strong year-classes of West Kamchatka pink salmon

Известия ТИНРО
Dynamics of downstream migration is considered for juvenile pink salmon at West Kamchatka in 1975–2023. Lengthening of the migration period is noted for recent years with high parental stocks.
N. A. Dederer, E. A. Shevlyakov, S. V. Naydenko   +2 more
doaj   +1 more source

Human fibroblast interferon RNA transcripts of different sizes in poly(I).poly(C) induced cells [PDF]

, 1983
A
Content, Jean, De Wit, Lucas, Fiers, Walter, Tavernier, Jan   +3 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Results of the count of juvenile pink salmon Oncorhynchus gorbuscha in the Malaya Khuzi River (Sakhalin Island) in 2022–2024

Известия ТИНРО
Migration of juvenile pink salmon Oncorhynсhus gorbuscha in the Malaya Khuzi River (northeastern Sakhalin Island) was studied in May-July of 2022, 2023 and 2024.
A. N. Elnikov, A. A. Zhivoglyadov, О. V. Zelennikov   +2 more
doaj   +1 more source

SUIVI DE LA MIGRATION D’AVALAISON DES ANGUILLES PAR UNE CONDUITE DE DEBIT RESERVE

Knowledge and Management of Aquatic Ecosystems, 2003
Le suivi de la migration catadrome de l’anguille par une conduite de débit réservé a été réalisé sur le barrage de la retenue de Bois Joli sur le Frémur (dénivelé : 13,7 m ; 3 millions de m3). Une partie des migrateurs utilise cette conduite, au début de
LEGAULT A., ACOU A., GUILLOUËT J., FEUNTEUN E.   +3 more
doaj   +1 more source

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin. [PDF]

, 2014
A long-standing issue in the field of signal transduction is to understand the cross-talk between receptor tyrosine kinases (RTKs) and heterotrimeric G proteins, two major and distinct signaling hubs that control eukaryotic cell behavior.
Abagyan, Ruben, Aznar, Nicolas, Ear, Jason, Garcia-Marcos, Mikel, Ghosh, Pradipta, Kufareva, Irina, Lin, Changsheng, Lopez-Sanchez, Inmaculada, Midde, Krishna   +8 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

La dévalaison des migrateurs : problèmes et dispositifs

Knowledge and Management of Aquatic Ecosystems, 1999
Cet article, qui actualise le chapitre 13 du n°326-327 du Bulletin Français de la Pêche et de la Pisciculture des mêmes auteurs, fait le bilan des connaissances actuelles sur la migration de dévalaison au niveau des centrales hydroélectriques, que ce ...
LARINIER M., TRAVADE F.
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source