Results 51 to 60 of about 176,716 (160)

Cardiomyocyte-specific knockout of ADAM17 alleviates doxorubicin-induced cardiomyopathy via inhibiting TNFα–TRAF3–TAK1–MAPK axis

Signal Transduction and Targeted Therapy
The pathogenesis of doxorubicin-induced cardiomyopathy remains unclear. This study was carried out to test our hypothesis that ADAM17 aggravates cardiomyocyte apoptosis induced by doxorubicin and inhibition of ADAM17 may ameliorate doxorubicin-induced ...
Lin Xie, Fei Xue, Cheng Cheng, Wenhai Sui, Jie Zhang, Linlin Meng, Yue Lu, Wenjing Xiong, Peili Bu, Feng Xu, Xiao Yu, Bo Xi, Lin Zhong, Jianmin Yang, Cheng Zhang, Yun Zhang   +15 more
doaj   +1 more source

Notch signaling pathway mediates Doxorubicin-driven apoptosis in cancers

Cancer Management and Research, 2018
Zixin Huang,1,* Shuibin Lin,2,* Chongde Long,1 Xin Zhou,1 Yuting Fan,1 Xielan Kuang,1,3 Jia He,1 Jie Ning,1 Han Zhang,1 Qingjiong Zhang,1 Huangxuan Shen1,3 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University ...
Huang Z, Lin S, Long C, Zhou X, Fan Y, Kuang X, He J, Ning J, Zhang H, Zhang Q, Shen H   +10 more
doaj  

Safety and efficacy of combination therapy with apatinib and doxorubicin in metastatic soft tissue sarcomas: an observational study from multiple institutions

Cancer Management and Research, 2019
Zhichao Tian,1 Xin Wang,1 Zhiyong Liu,1 Jiaqiang Wang,1 Weitao Yao,1 Yao Zhao,2 Songtao Gao,3 Peng Zhang,1 Hong Ge41Department of Orthopedics, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, Henan Province, People’s ...
Tian Z, Wang X, Liu Z, Wang J, Yao W, Zhao Y, Gao S, Zhang P, Ge H   +8 more
doaj  

Complexed rifampicin with iron mitigates doxorubicin-induced nephrotoxicity. [PDF]

BMC Pharmacol Toxicol
Basal OA, Saad EA, El Sadda RR.
europepmc   +1 more source

Transcriptomic Signatures Associated with Doxorubicin Treatment in Liposarcoma Reveal Coordinated Regulatory Patterns. [PDF]

Diseases
Khaleel A, Khaleel S, Ahmed RM, Al Athamneh A, Elsahoryi NA, Ali Agha ASA.   +5 more
europepmc   +1 more source

ALDH3A2-mediated fatty acid synthesis induces ferroptosis and AML drug resistance. [PDF]

iScience
Huang Y, Zhao Y, Yan P, Long Z, Xia C, Jiang L, Zhang Y, Cheng J, Liu F, Wu Q, Zhou Z, Jiang X.   +11 more
europepmc   +1 more source

Synergistic senolytic-regenerative therapy significantly extends healthspan and lifespan. [PDF]

J Transl Med
Ichim TE, Markov N, Lopes G, Pascual KA, Evans A, Reznik R, Bykoriz V, Fortunati CA, Minev B, Ramos RA, Bajnath A, Lin E, Hu J, Marincola FM, Rath A, Barrett B, Jurow A, Sankhala KK, Furman D, Reznik BN.   +19 more
europepmc   +1 more source

In Vitro Characterization of Internalization Pathways and Cytotoxic Activity of Anti-HSPG2 Antibody-Drug Conjugates in MDA-MB-231-LM2 Cells. [PDF]

Cancers (Basel)
Shao Z, Morelli L, Blass BE, Efimov A, Panyam J.   +4 more
europepmc   +1 more source

Direct comparison of efficacy of combining ivermectin versus five first-line chemotherapy drugs with recombinant methioninase against colon-cancer cells. [PDF]

Front Oncol
Kim J, Han Q, Li S, Kang BM, Miyashi Y, Ishiguro T, Bouvet M, Hoffman RM.   +7 more
europepmc   +1 more source

Maintenance Liposomal Doxorubicin Following Induction Doxorubicin in Soft Tissue Sarcoma: A Single-Center Observational Study. [PDF]

Curr Oncol
Faco ADS, Salehi MA, Hodroj MH, Mozafari-Lorestani K, Moria FA, Noujaim J, Saleh RR.   +6 more
europepmc   +1 more source