Results 1 to 10 of about 167,098 (312)

Doxycycline in STI Prophylaxis—A Literature Review [PDF]

open access: diamondVenereology, 2023
Background: Since the implementation of pre-exposure prophylaxis (PrEP) in HIV prevention, a significant increase in the prevalence of other sexually transmitted infections (STIs) has been reported, especially among men who have sex with men (MSM ...
Andrzej Załęski   +3 more
doaj   +2 more sources

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia

open access: greenNeurobiology of Disease, 2009
Doxycycline, a tetracycline antibiotic inhibits matrix metalloproteinase (MMP) and reduces neuronal damage in focal brain ischemia. This study was undertaken to assess if doxycycline reduces delayed neuronal damage following transient global cerebral ...
Hyung Lee   +4 more
doaj   +2 more sources

Doxycycline Attenuates Doxorubicin-Induced Cardiotoxicity by Improving Myocardial Energy Metabolism in Rats

open access: yesJournal of Cardiovascular Development and Disease, 2022
Aim: Evaluate the influence of doxycycline, an anti-inflammatory and matrix metalloproteinase (MMP) inhibitor, on the attenuation of chronic doxorubicin-induced cardiotoxicity in rats. Methods: We allocated male Wistar rats into four groups: control (C),
Danielle Dantas   +13 more
doaj   +1 more source

Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals.
Joseph D Turner   +12 more
doaj   +1 more source

Role of Integrin αvβ3 in Doxycycline-Induced Anti-Proliferation in Breast Cancer Cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Doxycycline, an antibiotic, displays the inhibition of different signal transduction pathways, such as anti-inflammation and anti-proliferation, in different types of cancers.
Yi-Fong Chen   +23 more
doaj   +1 more source

Why Does Doxycycline Pose a Relatively Low Risk for Promotion of Clostridioides difficile Infection?

open access: yesPathogens and Immunity, 2022
Background:  Clinical studies suggest that doxycycline poses a low risk for promotion of Clostridioides difficileinfection, but the microbiologic explanation for this finding is unclear.
Dongyan Xu   +6 more
doaj   +1 more source

Synthesis of Silver-Doxycycline Complex Nanoparticles and Their Biological Evaluation on MCF-7 Cell Line of the Breast Cancer

open access: yesJournal of Chemistry, 2021
In the current study, we aim to evaluate the effect of the combination of silver and doxycycline (silver-doxycycline complex) on the viability of the MCF-7 cell line of the breast in comparison with each of them.
Vahid Mohammadkarimi   +8 more
doaj   +1 more source

Doxycycline Attenuates Pig Intestinal Microbial Interactions and Changes Microbial Metabolic Pathways

open access: yesAnimals, 2023
Doxycycline is a therapeutic veterinary antibiotic commonly used in pig breeding. In this study, 27 fattening pigs of 33.5 ± 0.72 kg were divided equally into 3 groups.
Jiaojiao Xu   +10 more
doaj   +1 more source

Doxycycline Attenuated Ethanol-Induced Inflammaging in Endothelial Cells: Implications in Alcohol-Mediated Vascular Diseases

open access: yesAntioxidants, 2022
Excess alcohol consumption is a potential risk factor for cardiovascular diseases and is linked to accelerated aging. Drug discovery to reduce toxic cellular events of alcohol is required.
Xuanchen Li   +4 more
doaj   +1 more source

Investigation of a combination therapy approach for the treatment of melioidosis

open access: yesFrontiers in Microbiology, 2022
The efficacy of finafloxacin as a component of a layered defense treatment regimen was determined in vitro and in vivo against an infection with Burkholderia pseudomallei.
Kay B. Barnes   +9 more
doaj   +1 more source

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