Results 31 to 40 of about 150,359 (342)

Interest, concerns, and attitudes among men who have sex with men and healthcare providers toward prophylactic use of doxycycline against Chlamydia trachomatis infections and syphilis

Sexually Transmitted Diseases, 2021
A survey-based study found that community members who identify as men who have sex with men and health care providers in Southern California are likely to accept doxycycline preexposure/postexposure prophylaxis to prevent chlamydial infections and ...
Justin Park, C. Stafylis, D. Pearce, Jeff Taylor, S. Little, N. Kojima, Aleksandr M Gorin, J. Klausner   +7 more
semanticscholar   +1 more source

Doxycycline as an antimalarial : Impact on travellers’ diarrhoea and doxycycline resistance among various stool bacteria – Prospective study and literature review [PDF]

, 2022
Background: Antibiotics predispose travellers to acquire multidrug-resistant bacteria, such as extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE).
Anu Kantele, Sointu Mero, Kantele, Anu, Lääveri, Tinja, Tinja Lääveri, Mero, Sointu   +5 more
core   +1 more source

Resistance-guided antimicrobial therapy using doxycycline-moxifloxacin and doxycycline-2.5g azithromycin for the treatment of Mycoplasma genitalium infection: efficacy and tolerability.

Clinical Infectious Diseases, 2020
BACKGROUND Macrolide-resistance in Mycoplasma genitalium (MG) exceeds 50% in many regions and quinolone-resistance is increasing. We recently reported that resistance-guided therapy (RGT) using doxycycline followed by sitafloxacin or 2.5g-azithromycin ...
Duygu Durukan, T. Read, G. Murray, Michelle Doyle, E. Chow, L. Vodstrcil, C. Fairley, I. Aguirre, E. Mokany, L. Tan, Marcus Y. Chen, C. Bradshaw   +11 more
semanticscholar   +1 more source

Controlled randomized clinical trial on using Ivermectin with Doxycycline for treating COVID-19 patients in Baghdad, Iraq

medRxiv, 2020
Objectives: COVID-19 patients suffer from the lack of curative therapy. Hence, there is an urgent need to try repurposed old drugs on COVID-19. Methods: Randomized controlled study on 70 COVID-19 patients (48 mild-moderate, 11 severe, and 11 critical ...
H. Hashim, M. F. Maulood, A. M. Rasheed, D. F. Fatak, K. K. Kabah, A. Abdulamir   +5 more
semanticscholar   +1 more source

Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine

Scientific Reports, 2020
Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine.
S. Dijk, M. Protasoni, Marilena Elpidorou, A. Kroon, J. Taanman   +4 more
semanticscholar   +1 more source

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia

Neurobiology of Disease, 2009
Doxycycline, a tetracycline antibiotic inhibits matrix metalloproteinase (MMP) and reduces neuronal damage in focal brain ischemia. This study was undertaken to assess if doxycycline reduces delayed neuronal damage following transient global cerebral ...
Hyung Lee, Jong-Wook Park, Sang-Pyo Kim, Eng H. Lo, Seong-Ryong Lee   +4 more
doaj   +1 more source

Doxycycline as an initial treatment of bullous pemphigoid in Japanese patients

Journal of Cutaneous Immunology and Allergy, 2020
Objectives Tetracycline antibiotics have been used in bullous pemphigoid (BP) for their anti‐inflammatory effects. In Japan, tetracycline and minocycline, but not doxycycline, have been generally used in BP, although doxycycline has a better side‐effect ...
Kiyoto Kimura, Kazuhiro Kawai
doaj   +1 more source

Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice. [PDF]

PLoS ONE, 2012
There is no proven medical approach to attenuating expansion and rupture of abdominal aortic aneurysms (AAAs). One approach that is currently being investigated is the use of doxycycline. Despite being primarily used as an antimicrobial drug, doxycycline
Xiaojie Xie, Hong Lu, Jessica J Moorleghen, Deborah A Howatt, Debra L Rateri, Lisa A Cassis, Alan Daugherty   +6 more
doaj   +1 more source

Doxycycline PEP can induce doxycycline resistance in Klebsiella pneumoniae in a Galleria mellonella model of PEP

Frontiers in Microbiology, 2023
BackgroundFour randomized controlled trials have now established that doxycycline post exposure (sex) prophylaxis (PEP) can reduce the incidence of chlamydia and syphilis in men who have sex with men.
Chris Kenyon, Chris Kenyon, Zina Gestels, Thibaut Vanbaelen, Said Abdellati, Dorien Van Den Bossche, Irith De Baetselier, Basil Britto Xavier, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil   +9 more
doaj   +1 more source

Doxycycline-mediated effects on persistent symptoms and systemic cytokine responses post-neuroborreliosis: a randomized, prospective, cross-over study

BMC Infectious Diseases, 2012
Background Persistent symptoms after treatment of neuroborreliosis (NB) are well-documented, although the causative mechanisms are mainly unknown. The effect of repeated antibiotic treatment has not been studied in detail.
Sjöwall Johanna, Ledel Anna, Ernerudh Jan, Ekerfelt Christina, Forsberg Pia   +4 more
doaj   +1 more source