Results 31 to 40 of about 159,147 (288)
Background: Dengue fever is a mosquito borne disease commonly manifest leucopoenia and thrombocytopenia. Dengue fever and its complications like bleeding manifestation can be life threatening.
Vivek Pambhar +7 more
doaj +1 more source
MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury [PDF]
Murine double minute-2 (MDM2) is an E3-ubiquitin ligase and the main negative regulator of tumor suppressor gene p53. MDM2 has also a non-redundant function as a modulator of NF-kB signaling. As such it promotes proliferation and inflammation.
Anders, Hans-Joachim +10 more
core +2 more sources
Antibiotics in acute bronchitis: a meta-analysis. [PDF]
PurposeMost patients with acute bronchitis who seek medical care are treated with antibiotics, although the effectiveness of this intervention is uncertain.
Bent, S +3 more
core +1 more source
Dengue and Scrub Typhus Coinfection: A Diagnostic Dilemma
Due to overlapping clinical features, scrub typhus infection may be missed in presence of dengue. Concurrent infection with those two pathogens is rare and creates a diagnostic dilemma. We present a case of a 65-year-old male who was admitted with a high-
Atanu Chandra +5 more
doaj +1 more source
Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast [PDF]
Acknowledgments We thank Rebecca Shapiro for creating CaLC1819, CaLC1855 and CaLC1875, Gillian Milne for help with EM, Aaron Mitchell for generously providing the transposon insertion mutant library, Jesus Pla for generously providing the hog1 hst7 ...
A Ali +110 more
core +3 more sources
Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo +2 more
core +2 more sources
Background: Periodontal ligament fibroblasts (PDLF) play a key role in periodontal wound healing and tooth-supporting structures. Various approaches have been tried to enhance the fibroblastic activity such as laser irradiation or doxycycline application.
Alireza Dehdashtizadeh +4 more
doaj +1 more source
Doxycycline to treat levodopa-induced dyskinesias in Parkinson's disease: a preliminary study
Background Levodopa-induced dyskinesia (LID) is a common motor complication of levodopa therapy in patients with Parkinson's disease (PD). Doxycycline is a widely used and inexpensive tetracycline with anti-inflammatory properties.
Bruno Lopes Santos-Lobato +5 more
doaj +1 more source
An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma [PDF]
The conserved Myb-MuvB (MMB) multiprotein complex has an important role in transcriptional activation of mitotic genes. MMB target genes are overexpressed in several different cancer types and their elevated expression is associated with an advanced ...
Francke, S. +10 more
core +2 more sources
Objectives: To describe a series of doxycycline-induced fixed drug eruptions (FDE) observed in sexual health clinics, in a context of increasing doxycycline use for sexually transmitted infection (STI) management and prophylaxis in France.
Clément Brun +13 more
doaj +1 more source

