Results 21 to 30 of about 99,202 (246)

Doxycycline as an initial treatment of bullous pemphigoid in Japanese patients

Journal of Cutaneous Immunology and Allergy, 2020
Objectives Tetracycline antibiotics have been used in bullous pemphigoid (BP) for their anti‐inflammatory effects. In Japan, tetracycline and minocycline, but not doxycycline, have been generally used in BP, although doxycycline has a better side‐effect ...
Kiyoto Kimura, Kazuhiro Kawai
doaj   +1 more source

Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice. [PDF]

PLoS ONE, 2012
There is no proven medical approach to attenuating expansion and rupture of abdominal aortic aneurysms (AAAs). One approach that is currently being investigated is the use of doxycycline. Despite being primarily used as an antimicrobial drug, doxycycline
Xiaojie Xie, Hong Lu, Jessica J Moorleghen, Deborah A Howatt, Debra L Rateri, Lisa A Cassis, Alan Daugherty   +6 more
doaj   +1 more source

Dengue and Scrub Typhus Coinfection: A Diagnostic Dilemma

Oman Medical Journal, 2023
Due to overlapping clinical features, scrub typhus infection may be missed in presence of dengue. Concurrent infection with those two pathogens is rare and creates a diagnostic dilemma. We present a case of a 65-year-old male who was admitted with a high-
Atanu Chandra, Arkapravo Hati, Aritra Kumar Ray, Uddalak Chakraborty, Partha Sarathi Karmakar, Sugata Dasgupta   +5 more
doaj   +1 more source

Doxycycline to treat levodopa-induced dyskinesias in Parkinson's disease: a preliminary study

Arquivos de Neuro-Psiquiatria, 2023
Background Levodopa-induced dyskinesia (LID) is a common motor complication of levodopa therapy in patients with Parkinson's disease (PD). Doxycycline is a widely used and inexpensive tetracycline with anti-inflammatory properties.
Bruno Lopes Santos-Lobato, Manuelina Mariana Capellari Macruz Brito, Ângela Vieira Pimentel, Rômulo Torres Oliveira Cavalcanti, Elaine Del-Bel, Vitor Tumas   +5 more
doaj   +1 more source

Doxycycline-induced fixed drug eruption: A case series highlighting a dermatological concern in antimicrobial stewardship

International Journal of Infectious Diseases
Objectives: To describe a series of doxycycline-induced fixed drug eruptions (FDE) observed in sexual health clinics, in a context of increasing doxycycline use for sexually transmitted infection (STI) management and prophylaxis in France.
Clément Brun, Marie Danset, Romain Salle, Victor Bourdenet, Louise Jaulent, Florence Hacard, Marine Fargeas, Brigitte Milpied, Elisa Goujon, Valérie Beaulieu, Timothy Capeliez, Sébastien Fouéré, Matthieu Godinot, Marie Tauber   +13 more
doaj   +1 more source

Doxycycline Proniosomal Gel as Local Drug Delivery System in Periodontal Disease: A Vitro Study

Journal of Pharmacy and Bioallied Sciences
Background: Periodontitis is an inflammatory condition of the oral cavity in which microorganisms play a significant role in the pathogenesis and onset.
Dhawal Rajendra Mody, Vrushali Lathiya, Abhay P. Kolte, Vaishnavi Biradar, Vaishnavi Langde   +4 more
doaj   +1 more source

The effect of laser irradiation and doxycycline application on the production of matrix metalloproteinase-8 and collagen I from cultured human periodontal ligament cells

Dental Research Journal, 2020
Background: Periodontal ligament fibroblasts (PDLF) play a key role in periodontal wound healing and tooth-supporting structures. Various approaches have been tried to enhance the fibroblastic activity such as laser irradiation or doxycycline application.
Alireza Dehdashtizadeh, Nasim Esnaashari, Shirin Zahra Farhad, Fatemeh Ejeian, Shaharam Amini   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Microwave-Assisted, One-Pot Synthesis of Doxycycline under Heterogeneous Catalysis in Water

Antibiotics, 2021
The selective synthesis of active pharmaceutical molecules is a challenging issue, particularly when attempting to make the reactions even more sustainable.
Fabio Bucciol, Elia Maffeis, Emanuela Calcio Gaudino, László Jicsinszky, Silvia Tagliapietra, Alessandro Barge, Cristina Prandi, Giancarlo Cravotto   +7 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source