Results 21 to 30 of about 25,207 (238)

Rumen Microbiota Distribution Analyzed by High-Throughput Sequencing After Oral Doxycycline Administration in Beef Cattle

Frontiers in Veterinary Science, 2020
The beef cattle rumen is a heterogenous microbial ecosystem that is necessary for the host to digest food and support growth. The importance of the rumen microbiota (RM) is also widely recognized for its critical roles in metabolism and immunity.
Fengmei Chen, Guangmin Cheng, Yulin Xu, Yulin Xu, Yulin Xu, Yulin Xu, Yunzhou Wang, Qingxiang Xia, Shilin Hu   +8 more
doaj   +1 more source

Investigation of a combination therapy approach for the treatment of melioidosis

Frontiers in Microbiology, 2022
The efficacy of finafloxacin as a component of a layered defense treatment regimen was determined in vitro and in vivo against an infection with Burkholderia pseudomallei.
Kay B. Barnes, Mark I. Richards, Gary Burgess, Stuart J. Armstrong, Christine Bentley, Thomas C. Maishman, Thomas R. Laws, Michelle Nelson, Sarah V. Harding, Sarah V. Harding   +9 more
doaj   +1 more source

Doxycycline Attenuated Ethanol-Induced Inflammaging in Endothelial Cells: Implications in Alcohol-Mediated Vascular Diseases

Antioxidants, 2022
Excess alcohol consumption is a potential risk factor for cardiovascular diseases and is linked to accelerated aging. Drug discovery to reduce toxic cellular events of alcohol is required.
Xuanchen Li, Dilaware Khan, Majeed Rana, Daniel Hänggi, Sajjad Muhammad   +4 more
doaj   +1 more source

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Luft, F.C., Mueller, D.N., Lydia Hering, Morton, J., Davidge, ST, Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Florian Herse, Ralf Dechend, Dudenhausen, J.W., Nele Geusens, Cartwright, J.E., Geusens, N., Verhaegen, I., Jude Morton, Morton, J, Hering, L, Iris Verhaegen, Dominik N. Muller, Dechend, R., Sandra T. Davidge, Joachim W. Dudenhausen, Hering, L., Davidge, S.T., Verlohren, S, Verhaegen, I, Dudenhausen, JW, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
core   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Schöllmann, C., Korting, Hans Christian, C. Schöllmann, H.C. Korting   +3 more
core   +1 more source

Doxycycline PEP can induce doxycycline resistance in Klebsiella pneumoniae in a Galleria mellonella model of PEP

Frontiers in Microbiology, 2023
BackgroundFour randomized controlled trials have now established that doxycycline post exposure (sex) prophylaxis (PEP) can reduce the incidence of chlamydia and syphilis in men who have sex with men.
Chris Kenyon, Chris Kenyon, Zina Gestels, Thibaut Vanbaelen, Said Abdellati, Dorien Van Den Bossche, Irith De Baetselier, Basil Britto Xavier, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil   +9 more
doaj   +1 more source

The inhibitory effect of doxycycline on cisplatin-sensitive and -resistant epithelial ovarian cancer.

PLoS ONE, 2014
BackgroundDetecting a new effective and hypotoxic anticancer drug is an emerging new strategy for cancer chemotherapy. Doxycycline (DC) is a kind of antibiotics but also inhibits tumorigenesis.MethodsMTT and cell invasion assay, flow cytometry, western ...
Wei Wu, Li-Hua Yu, Bei Ma, Ming-Juan Xu
doaj   +1 more source

Safety and efficacy of doxycycline

, 2009
Doxycycline has remained one of the most commonly used and inexpensive of the broad-spectrum antibiotic drugs currently in use. It has a variety of applications to common respiratory and genitourinary tract infections, but also amongst atypical ...
Peter A. Leggat, Leggat, Peter A.
core   +2 more sources

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia

Neurobiology of Disease, 2009
Doxycycline, a tetracycline antibiotic inhibits matrix metalloproteinase (MMP) and reduces neuronal damage in focal brain ischemia. This study was undertaken to assess if doxycycline reduces delayed neuronal damage following transient global cerebral ...
Hyung Lee, Jong-Wook Park, Sang-Pyo Kim, Eng H. Lo, Seong-Ryong Lee   +4 more
doaj   +1 more source

Doxycycline sensitizes renal cell carcinoma to chemotherapy by preferentially inhibiting mitochondrial translation

Journal of International Medical Research, 2021
Objectives The anti-cancer activity of doxycycline has been reported in many cancers but not renal cell carcinoma (RCC). This study aimed to determine the efficacy of doxycycline alone and in combination with paclitaxel and analyze the underlying ...
Bo Wang, Jinsong Ao, Xiaoyan Li, Weimin Yu, Dan Yu, Chengjun Qiu   +5 more
doaj   +1 more source