Results 51 to 60 of about 95,266 (202)

Comparison of serological response to doxycycline versus benzathine penicillin G in the treatment of early syphilis in HIV-infected patients: a multi-center observational study. [PDF]

PLoS ONE, 2014
BACKGROUND: While doxycycline is recommended as an alternative treatment of syphilis in patients with penicillin allergy or intolerance, clinical studies to compare serological response to doxycycline versus benzathine penicillin in treatment of early ...
Jen-Chih Tsai, Yu-Huei Lin, Po-Liang Lu, Ni-Jiin Shen, Chia-Jui Yang, Nan-Yao Lee, Hung-Jen Tang, Yuag-Meng Liu, Wen-Chi Huang, Chen-Hsiang Lee, Wen-Chien Ko, Yen-Hsu Chen, Hsi-Hsun Lin, Tun-Chieh Chen, Chien-Ching Hung   +14 more
doaj   +1 more source

Doxycycline for the treatment of breast cancer-related lymphedema

Frontiers in Pharmacology, 2022
Purpose: Secondary lymphedema is a common complication of cancer treatment for which no effective drug treatments yet exist. Level I clinical data suggests that doxycycline is effective for treating filariasis-induced lymphedema, in which it decreases ...
Stav Brown, Joseph H. Dayan, Michelle Coriddi, Leslie McGrath, Raghu P. Kataru, Babak J. Mehrara   +5 more
doaj   +1 more source

Suppression of MMP-9 by doxycycline in brain arteriovenous malformations

BMC Neurology, 2005
Background The primary aim of this study is to demonstrate the feasibility of utilizing doxycycline to suppress matrix metalloproteinase-9 (MMP-9) in brain arteriovenous malformations (AVMs).
Li Jenny F, Matsumoto Melissa M, Hashimoto Tomoki, Lawton Michael T, Young William L   +4 more
doaj   +1 more source

Demystifying pyrexia of unknown origin: A case of splenic brucellosis

Journal of Marine Medical Society, 2022
Brucellosis is a zoonotic infectious disease, which mainly involves lymphoreticular system. Our case report describes an isolated splenic lesion diagnosed in a 48-year-old individual who is a farmer by occupation, had a history of animal contact, and has
Manish Kumar, Anuj Singhal, Vikram Singh, Asima Bushra, Bhairavabhatla V S. P. Viswanadh, K K Kiran   +5 more
doaj   +1 more source

Doxycycline preserves chondrocyte viability and function in human and calf articular cartilage ex vivo

Physiological Reports, 2020
Prolonging chondrocyte survival is essential to ensure fresh osteochondral (OC) grafts for treatment of articular cartilage lesions. Doxycycline has been shown to enhance cartilage growth, disrupt terminal differentiation of chondrocytes, and inhibit ...
Li Yue, Brian Vuong, Hongwei Yao, Brett D. Owens   +3 more
doaj   +1 more source

Pharmacokinetics of Doxycycline in Plasma and Milk after Intravenous and Intramuscular Administration in Dairy Goats

Animals
Doxycycline is a second-generation tetracycline, marketed in different species for treating infections caused by susceptible bacteria. Little information is available on the pharmacokinetics of doxycycline in lactating goats.
José Martínez, Elisa Escudero, Elena Badillo, María Teresa Yuste, Juan Sebastián Galecio, Pedro Marin   +5 more
doaj   +1 more source

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Neurobiology of Disease, 2021
Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders characterized by the misfolding and aggregation of alpha-synuclein (aSyn).
Antonio Dominguez-Meijide, Valeria Parrales, Eftychia Vasili, Florencia González-Lizárraga, Annekatrin König, Diana F. Lázaro, Annie Lannuzel, Stéphane Haik, Elaine Del Bel, Rosana Chehín, Rita Raisman-Vozari, Patrick P. Michel, Nicolas Bizat, Tiago Fleming Outeiro   +13 more
doaj  

An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition

Lung India, 2011
Background: Idiopatiic pulmonary fibrosis (IPF) is a disease of dysregulated fibrogenesis with abnormal matrix metalloproteinase (MMPs) activity, angiogenesis, and profibrotic milieu wherein MMPs inhibition appears to be target-based therapy.
Amartya Mishra, Parthasarathi Bhattacharya, Sumit Paul, Rantu Paul, Snehasikta Swarnakar   +4 more
doaj   +1 more source

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia

Neurobiology of Disease, 2009
Doxycycline, a tetracycline antibiotic inhibits matrix metalloproteinase (MMP) and reduces neuronal damage in focal brain ischemia. This study was undertaken to assess if doxycycline reduces delayed neuronal damage following transient global cerebral ...
Hyung Lee, Jong-Wook Park, Sang-Pyo Kim, Eng H. Lo, Seong-Ryong Lee   +4 more
doaj  

To Doxycycline with Love [PDF]

Advances in Ophthalmology & Visual System, 2014
After more than 60 years of the discovery it is still used in our daily practice, Doxycycline as we know is a long-acting second generation synthetic tetracycline derivative with similar antimicrobial activity with somehow less side effects, act on bacterial ribosomes, preventing them from effectively translating mRNA into vital proteins, and inhibits ...
openaire   +2 more sources