Results 141 to 150 of about 16,540 (179)
Unique Role of Proximal Tubule Dipeptidyl Peptidase 4 on Blood Pressure, Renal Sodium Handling, and Na<sup>+</sup>/H<sup>+</sup> Exchanger Isoform 3 Phosphorylation. [PDF]
Acta Physiol (Oxf)Martins FL +4 more
europepmc +1 more source
DPP4 Activity, Hyperinsulinemia, and Atherosclerosis
Journal of Clinical Endocrinology and Metabolism, 2021 Abstract Context Obesity and type 2 diabetes are associated with chronic hyperinsulinemia, elevated plasma levels of dipeptidyl peptidase-4 (DPP4), and a pro-atherosclerotic milieu. Evidence Acquisition PubMed search of the term ...
Kaitlin M Love, Zhenqi Liu, Liu Zhenqi
exaly +4 more sources
The Roles of Dipeptidyl Peptidase 4 (DPP4) and DPP4 Inhibitors in Different Lung Diseases: New Evidence [PDF]
Frontiers in Pharmacology, 2021 CD26/Dipeptidyl peptidase 4 (DPP4) is a type II transmembrane glycoprotein that is widely expressed in various organs and cells. It can also exist in body fluids in a soluble form. DPP4 participates in various physiological and pathological processes by regulating energy metabolism, inflammation, and immune function.
Tianli Zhang +2 more
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DPP4 in Cardiometabolic Disease [PDF]
Circulation Research, 2015 The discovery of incretin-based medications represents a major therapeutic advance in the pharmacological management of type 2 diabetes mellitus (T2DM), as these agents avoid hypoglycemia, weight gain, and simplify the management of T2DM. Dipeptidyl peptidase-4 (CD26, DPP4) inhibitors are the most widely used incretin-based therapy for the treatment of
Jixin Zhong +2 more
exaly +3 more sources
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The protective role of DPP4 inhibitors in atherosclerosis
European Journal of Pharmacology, 2020Diabetes is a chronic non-communicable disease whose incidence continues to grow rapidly, and it is one of the most serious and critical public health problems. Diabetes complications, especially atherosclerosis-related chronic vascular complications, are a serious threat to human life and health.
Hengdao, Liu +9 more
openaire +2 more sources
Significance of circulatory DPP4 activity in metabolic diseases [PDF]
IUBMB Life, 2018 AbstractDipeptidyl peptidase 4 (DPP4), also known as CD26 is a type II transmembrane protein that is released from the cell membrane in a nonclassical secretory mechanism. This exopeptidase selectively degrades varieties of substrates including incretin hormones, growth factors, and cytokines.
Titli Nargis, Partha Chakrabarti
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