Results 1 to 10 of about 5,096 (138)

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2-Modulated Exosome Release. [PDF]

Adv Sci (Weinh)
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Jin B, Dong S, Jia Y, Xu Z, Liu P, Ding Z, Liao Y, Zou R, Hu J, Cheng B, Niu L.   +10 more
europepmc   +2 more sources

Cellular Properties and Expression of Pluripotent Markers in Human Dental Pulp Stem Cells Cultured in Serum-Free Medium [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: The standard isolation and expansion of human Dental Pulp Stem Cells (DPSCs) under invitro conditions normally involve the usage of Fetal Bovine Serum (FBS).
Chethan Kumar, Basan Gowda Sharanappa Kurkalli, Shishir Shetty, AKSHAY BAIRAPURA MANJA, Veena Shetty, Mohana Kumar Basavarajappa   +5 more
doaj   +1 more source

Cigarette smoking exposure disrupts the regenerative potential of dental pulp stem cells

Tobacco Induced Diseases, 2023
Introduction Smoking is known to alter the regenerative and immunomodulatory properties of many types of mesenchymal stem cells (MSCs). This study investigates the impact of cigarette smoke exposure on the regenerative potential of dental pulp stem cells
Leyla Tahrani Hardin, David Vang, Der Thor, Xiaoyuan Han, Fatima Mashkoor, Tamer Alpagot, David Ojcius, Nan Xiao   +7 more
doaj   +1 more source

Age of the donor affects the nature of in vitro cultured human dental pulp stem cells

Saudi Dental Journal, 2021
Objectives: The dental pulp stem cells (DPSCs) of six donors (three young donors aged  25 and 
Heba Alzer, Heba Kalbouneh, Firas Alsoleihat, Nisreen Abu Shahin, Soukaina Ryalat, Mohammad Alsalem, Hazem Alahmad, Lubna Tahtamouni   +7 more
doaj   +1 more source

Biological characteristics and pulp regeneration potential of stem cells from canine deciduous teeth compared with those of permanent teeth

Stem Cell Research & Therapy, 2022
Background Clinical studies have demonstrated that dental pulp stem cells isolated from permanent teeth (PT-DPSCs) are safe and efficacious for complete pulp regeneration in mature pulpectomized permanent teeth with complete apical closure.
S. M. Ziauddin, Misako Nakashima, Hideto Watanabe, Michiyo Tominaga, Koichiro Iohara   +4 more
doaj   +1 more source

Dental pulp stem cells stimulate neuronal differentiation of PC12 cells

Neural Regeneration Research, 2021
Dental pulp stem cells (DPSCs) secrete neurotrophic factors which may play an important therapeutic role in neural development, maintenance and repair.
Nessma Sultan, Laila E Amin, Ahmed R Zaher, Mohammed E Grawish, Ben A Scheven   +4 more
doaj   +1 more source

Microarray analysis of long non-coding RNAs related to osteogenic differentiation of human dental pulp stem cells

Journal of Dental Sciences, 2022
Background/purpose: Dental pulp stem cells (DPSCs) are candidate seed cells for bone tissue engineering, but the molecular regulation of osteogenic differentiation in DPSCs is not fully understood.
Xinyu Hao, Dongfang Li, Dongjiao Zhang, Linglu Jia   +3 more
doaj   +1 more source

CircRFWD2 Promotes Osteogenic Differentiation of human Dental Pulp Stem Cells by Targeting miR-6817-5p Through BMP-Smad and p38 MAPK Pathway

Cell Transplantation, 2021
Dental pulp stem cells (DPSCs) are one promising cell source of mesenchymal stem cells in bone tissue engineering. However, it remains unknown that the molecules and signaling pathways involved in osteogenesis of DPSCs. Hence, this study investigated the
Xinqi Huang, Xuefeng Pan, Bo Zhang, Wei Huang, Xiao Cen, Jun Liu, Zhihe Zhao   +6 more
doaj   +1 more source

Silencing VEGFR-2 Hampers Odontoblastic Differentiation of Dental Pulp Stem Cells

Frontiers in Cell and Developmental Biology, 2021
Dental pulp stem cells (DPSCs) are a source of postnatal stem cells essential for maintenance and regeneration of dentin and pulp tissues. Previous in vivo transplantation studies have shown that DPSCs are able to give rise to odontoblast-like cells ...
Kajohnkiart Janebodin, Kajohnkiart Janebodin, Kajohnkiart Janebodin, Rakchanok Chavanachat, Aislinn Hays, Aislinn Hays, Aislinn Hays, Morayma Reyes Gil   +7 more
doaj   +1 more source

Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells

Biomolecules, 2023
Strategies to promote dental pulp stem cells (DPSCs) functions including proliferation, migration, pro-angiogenic effects, and odontogenic/osteogenic differentiation are in urgent need to restore pulpitis-damaged dentin/pulp regeneration and DPSCs-based ...
Lina Yu, Liting Zeng, Zeyu Zhang, Guanxiong Zhu, Zidan Xu, Junyi Xia, Jinlong Weng, Jiang Li, Janak Lal Pathak   +8 more
doaj   +1 more source