Results 21 to 30 of about 7,144 (222)

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis

open access: yesStem Cell Research & Therapy, 2020
Background To investigate the odonto-immunomodulatory properties of dental pulp stem cell-derived small extracellular vesicles (DPSCs-sEV), which promote odontogenesis by switching macrophages toward the pro-healing M2 phenotype.
Jianmao Zheng   +7 more
doaj   +1 more source

Growth Factor Liberation and DPSC Response Following Dentine Conditioning [PDF]

open access: yesJournal of Dental Research, 2016
Liberation of the sequestrated bioactive molecules from dentine by the action of applied dental materials has been proposed as an important mechanism in inducing a dentinogenic response in teeth with viable pulps. Although adhesive restorations and dentine-bonding procedures are routinely practiced, clinical protocols to improve pulp protection and ...
Sadaghiani, Leili   +5 more
openaire   +2 more sources

Structural and Functional Studies of the Daunorubicin Priming Ketosynthase DpsC [PDF]

open access: yesACS Chemical Biology, 2017
Daunorubicin is a type II polyketide, one of a large class of polyaromatic natural products with anticancer, antibiotic, and antiviral activity. Type II polyketides are formed by the assembly of malonyl-CoA building blocks, though in rare cases, biosynthesis is initiated by the incorporation of a nonmalonyl derived starter unit, which adds molecular ...
David R. Jackson   +10 more
openaire   +4 more sources

Characterization of dental pulp stem/stromal cells of Huntington monkey tooth germs

open access: yesBMC Cell Biology, 2011
Background Dental pulp stem/stromal cells (DPSCs) are categorized as adult stem cells (ASCs) that retain multipotent differentiation capabilities. DPSCs can be isolated from individuals at any age and are considered to be true personal stem cells, making
Yang Jinjing   +5 more
doaj   +1 more source

Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation

open access: yesBMC Oral Health, 2021
Background During the process of deep decay, when decay approaches the pulp, an immune response is triggered inside the pulp, which activates the complement cascade.
Jie Liu   +10 more
doaj   +1 more source

Lysine 68 Methylation‐Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells

open access: yesAdvanced Science, 2023
Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering.
Qiannan Sun   +7 more
doaj   +1 more source

Effects of SOX2 on Proliferation, Migration and Adhesion of Human Dental Pulp Stem Cells. [PDF]

open access: yesPLoS ONE, 2015
As a key factor for cell pluripotent and self-renewing phenotypes, SOX2 has attracted scientists' attention gradually in recent years. However, its exact effects in dental pulp stem cells (DPSCs) are still unclear.
Pengfei Liu   +6 more
doaj   +1 more source

Human Dental Pulp Stem Cells Exhibit Osteogenic Differentiation Potential

open access: yesOpen Life Sciences, 2020
Bone regeneration after trauma, pathologic and surgical procedures is considered a major medical challenge. Due to limitations in using conventional approaches, cell based regenerative strategies may provide an alternative option to address such issues ...
Awais Sadia   +3 more
doaj   +1 more source

Hypoxia Induces DPSC Differentiation versus a Neurogenic Phenotype by the Paracrine Mechanism

open access: yesBiomedicines, 2022
As previously described by several authors, dental pulp stem cells (DPSCs), when adequately stimulated, may acquire a neuronal-like phenotype acting as a favorable source of stem cells in the generation of nerves. Besides, it is known that hypoxia conditioning is capable of stimulating cell differentiation as well as survival and self-renewal, and that
Simona Delle Monache   +8 more
openaire   +6 more sources

Synergistic actions of DPSCs and ECs in vascularising bioengineered pulp

open access: yes, 2012
Pulp Biology & Regeneration Research 80 - Dental Pulp Cells and Stem Cells (Poster Session): no ...
Hargreaves, KM   +3 more
openaire   +2 more sources

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