Results 31 to 40 of about 7,982,988 (250)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Promoting Mindfulness about the Environment through the Use of Drama in the Primary Classroom: Greek Teachers’ Views and Attitudes

Education Sciences, 2019
The present questionnaire-based study examines Greek teachers’ views and attitudes towards drama-based activities in primary education classrooms when conducting Environmental Education programs. More specifically, 330 teachers provided information about
Evanthia Andrikopoulou, Konstantina Koutrouba   +1 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Between drama education and drama therapy: international approaches to successful navigation

, 2015
This article describes a workshop with approximately 30 drama educators, presented at the 2013 congress of the International Drama/Education Association (IDEA) that examined the overlap of drama education and drama therapy.
Holmwood, C.
core   +1 more source

Drama as a catalyst for experiential learning in early education: challenges and prospects under National Education Policy (NEP) 2020

International Journal of Child Care and Education Policy
Drama is widely recognized as an experiential pedagogical approach that supports children’s cognitive, social, emotional, and creative development. In India, the National Education Policy (NEP) 2020 emphasizes play-based, experiential, and holistic ...
Nirbhay Kumar Trigun, Anjuli Jain
doaj   +1 more source

Towards a problem-posing pedagogy: Using teacher-in-role in a special needs classroom

South African Journal of Childhood Education, 2022
Background: Teacher-in-role (t-i-r) drama method is explored as a pedagogical approach that can transform special needs curricula in South Africa. Aim: To use t-i-r to create a collaborative educational environment between learners and teachers.
Phemelo C. Hellemann
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Pantun in the Text of Nyanyian Lagu Melayu Asli (NLMA)

Harmonia: Journal of Arts Research and Education, 2018
The purpose of this study is to understand the role of pantun in the text of Nyanyian Lagu Melayu Asli (NLMA). By using critical descriptive method accompanied by implementation of content analysis theory, the author conducted literature studies ...
Tengku Ritawati
doaj   +1 more source