Results 61 to 70 of about 837,527 (297)

Influence of Drawing Speed and Blank Holding Force in Rectangular Drawing of Ultra Thin Sheet Metal [PDF]

Transactions of Materials Processing, 2012
Micro-drawn parts have received wider acceptance as products become smaller and more precise. The subject of this study was the deformation characteristics of ultra thin sheet metal in micro drawing of a rectangular shaped part. The influence of drawing speed and blank holding force on the product quality was investigated in micro-drawing of ultra thin
J.H. Lee, W.J. Chung, J.H. Kim
openaire   +1 more source

Network support for integrated design [PDF]

, 2003
A framework of network support for utilization of integrated design over the Internet has been developed. The techniques presented also applicable for Intranet/Extranet.
Chen, X, Su, D
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The simultaneity of complementary conditions:re-integrating and balancing analogue and digital matter(s) in basic architectural education [PDF]

, 2008
The actual, globally established, general digital procedures in basic architectural education,producing well-behaved, seemingly attractive up-to-date projects, spaces and first general-researchon all scale levels, apparently present a certain growing ...
Wiesner, Thomas
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Manufacture of Microstructured Optical Fibers: Problem of Optimal Control of Silica Capillary Drawing Process

Computation
The effective control of any technological process is essential in ensuring high-quality finished products. This is particularly true in manufacturing knowledge-intensive and high-tech products, including microstructured photonic crystal fibers (PCF ...
Daria Vladimirova, Vladimir Pervadchuk, Yuri Konstantinov   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

From on-line sketching to 2D and 3D geometry: A fuzzy knowledge based system [PDF]

, 2000
The paper describes the development of a fuzzy knowledge based prototype system for conceptual design. This real time system is designed to infer user’s sketching intentions, to segment sketched input and generate corresponding geometric primitives ...
Jordanov, IN, Qin, SF, Wright, DK
core  

Biomimetic Algorithms for Coordinated Motion: Theory and Implementation

, 2015
Drawing inspiration from flight behavior in biological settings (e.g. territorial battles in dragonflies, and flocking in starlings), this paper demonstrates two strategies for coverage and flocking.
Dey, Biswadip, Halder, Udit
core   +1 more source