Results 31 to 40 of about 163,636 (279)

A dried blood spot assay for paclitaxel and its metabolites [PDF]

open access: yes, 2018
After being used for decades in clinical screening, dried blood spots (DBS) have recently received considerable attention for their application in pharmacokinetic and toxicokinetic studies in rodents. The goal of this study was to develop and apply a DBS-
Colin, Pieter   +4 more
core   +1 more source

Dried Blood Spot Test Estimation of Urea [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1985
The analysis of urea in serum and whole blood samples dried onto filter paper has been investigated. In both cases the sample volume is not critical nor is the volume of sample applied to the filter paper if sample discs of consistent dimensions can be punched from the dried paper. The method must be calibrated by a serum-based material not an aqueous
R M, Plumbe, H G, Worth
openaire   +2 more sources

Dried blood spot testing for the antenatal screening of HTLV, HIV, syphilis, toxoplasmosis and hepatitis B and C: prevalence, accuracy and operational aspects

open access: yesBrazilian Journal of Infectious Diseases, 2014
Introduction: Screening for vertically transmitted infection is mandatory and must be conducted at the first prenatal consultation. The most vulnerable women's groups are those at the lowest socio-economic level.
Ney Boa-Sorte   +5 more
doaj   +1 more source

Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct 'on spot' derivatization [PDF]

open access: yes, 2010
The objective of this study was the development of an accurate and sensitive method for the determination of gamma-hydroxybutyric acid (GHB) in dried whole blood samples using a GC-MS method.
Ingels, Ann-Sofie   +2 more
core   +1 more source

Dried blood spot analysis; facing new challenges

open access: yesJournal of Applied Bioanalysis, 2015
Over the last decade, DBS analysis has gained popularity for TDM because it’s a patient friendly sampling proce- dure [1-4]. Additional advantages are prolonged sample stability, lower risk of infections and transportation at ambient temperature [1-3,5].
Koster, Remco A   +2 more
openaire   +2 more sources

Official International Association for Therapeutic Drug Monitoring and Toxicology guideline: Development and Validation of Dried Blood Spot-based Methods for Therapeutic Drug Monitoring.

open access: yesTherapeutic Drug Monitoring, 2019
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to facilitate Therapeutic Drug Monitoring (TDM). To assure the quality of bioanalytical methods, the design, development and validation needs to fit the intended use.
S. Capiau   +13 more
semanticscholar   +1 more source

Prosfektif Metode Sampel Darah Kering dalam Bioanalisis

open access: yesJournal of Tropical Pharmacy and Chemistry, 2016
Biosampling of dried blood spot method became lately very interested in bioanalysis, some of the advantages given in this method compared to conventional venous canulla (venipuncture); less invasive making it more pleasant for the patient or subject ...
Supandi Supandi
doaj   +1 more source

Nutrient intake, body composition, and blood phenylalanine control in children with phenylketonuria compared to healthy controls

open access: yesMolecular Genetics and Metabolism Reports, 2020
Background: Phenylketonuria (PKU) treatment consists of life-long protein restriction and Phe-free medical foods for adequate nutritional intake and growth.
Melissa Sailer   +4 more
doaj   +1 more source

Blood spots as an alternative to whole blood collection and the effect of a small monetary incentive to increase participation in genetic association studies

open access: yesBMC Medical Research Methodology, 2009
Background Collection of buccal cells from saliva for DNA extraction offers a less invasive and convenient alternative to venipuncture blood collection that may increase participation in genetic epidemiologic studies. However, dried blood spot collection,
Ringer Danny   +6 more
doaj   +1 more source

Use of Dried Blood Spot Specimens to Monitor Patients with Inherited Metabolic Disorders

open access: yesInternational Journal of Neonatal Screening, 2020
Monitoring of patients with inherited metabolic disorders (IMDs) using dried blood spot (DBS) specimens has been routinely used since the inception of newborn screening (NBS) for phenylketonuria in the 1960s.
S. Moat, Roanna S George, R. Carling
semanticscholar   +1 more source

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