Dronabinol Is Not a Game Changer in Pediatric Palliative Care: Results from a Retrospective Study [PDF]
Background/Objectives: Patients with life-limiting conditions (LLCs) often suffer from restlessness, spasticity, pain, and seizures. Dronabinol (DRB) may have a relieving effect; however, data on the effectiveness of DRB in children with LLCs are limited
Holger Hauch +3 more
doaj +4 more sources
Bioavailability study of dronabinol oral solution versus dronabinol capsules in healthy volunteers
Neha Parikh,1 William G Kramer,2 Varun Khurana,1 Christina Cognata Smith,1 Santosh Vetticaden,1 1INSYS Therapeutics, Inc., Chandler, AZ, USA; 2Kramer Consulting LLC, North Potomac, MD, USA Background: Dronabinol, a pharmaceutical Δ-9 ...
Parikh N +4 more
doaj +6 more sources
Treating nightmares in posttraumatic stress disorder with dronabinol: study protocol of a multicenter randomized controlled study (THC PTSD-trial) [PDF]
Background Distressing nightmares are a core symptom of posttraumatic stress disorder (PTSD) and contribute to psychiatric comorbidity, impaired physical health and decreased social functioning.
Stefan Roepke +9 more
doaj +4 more sources
Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran [PDF]
Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.
Kourosh Saki +8 more
doaj +2 more sources
Treatment of Chronic Intractable Neuropathetic Pain with Dronabinol: Case Report of Two Adolescents [PDF]
OBJECTIVE: To evaluate the effectiveness of dronabinol for the treatment of neuropathic pain refractory to previous treatment.
Zvia Rudich +3 more
doaj +2 more sources
D Alexander Oh, Neha Parikh, Varun Khurana, Christina Cognata Smith, Santosh VetticadenINSYS Therapeutics, Inc., Chandler, AZ, USA Abstract: Dronabinol is a pharmaceutical tetrahydrocannabinol originally developed as an oral capsule.
Oh DA +4 more
doaj +4 more sources
Impact of Low-Dose Dronabinol Therapy on Cognitive Function in Cancer Patients Receiving Palliative Care: A Case-Series Intervention Study [PDF]
Background: Cannabis may offer therapeutic benefits to patients with advanced cancer not responding adequately to conventional palliative treatment. However, tolerability is a major concern.
Ditte Buchwald +8 more
doaj +2 more sources
Proof of Concept Trial of Dronabinol in Obstructive Sleep Apnea [PDF]
Study Objective: Animal data suggest that ∆9-TetraHydroCannabinol (∆9THC) stabilizes autonomic output during sleep, reduces spontaneous sleep-disordered breathing and blocks serotonin-induced exacerbation of sleep apnea.
Bharati ePrasad +2 more
doaj +2 more sources
A pilot study of dronabinol for the treatment of pain in sickle cell disease [PDF]
Background Many adults living with sickle cell disease (SCD) suffer from chronic pain, turning to cannabis for relief. However, there are few studies that examine the efficacy of cannabis in treating pain associated with SCD.
Susanna A. Curtis +5 more
doaj +2 more sources
Rastafarianism: When Religious Beliefs Conflict With Medical Necessity—A Case Report and Review of the Literature Around an Ethically Complicated Case [PDF]
Discussion: This case exemplifies the complexities of clinical care when religious beliefs conflict with medical necessity. We discuss the limited indications for dronabinol and potential adverse effects on delirium’s behavioral symptoms.
Matthew Flick +2 more
doaj +2 more sources

